Search Results - "DODOO, Alexander"
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Adverse Drug Reaction Reporting in Africa and a Comparison of Individual Case Safety Report Characteristics Between Africa and the Rest of the World: Analyses of Spontaneous Reports in VigiBase
Published in Drug safety (01-04-2016)“…Introduction Following the start of the World Health Organization (WHO) Programme for International Drug Monitoring (PIDM) by 10 member countries in 1968, it…”
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Monitoring and risk assessment of pesticide residues in selected herbal medicinal products in Ghana
Published in Environmental monitoring and assessment (01-08-2021)“…The high patronage of herbal medicinal products in Ghana for the treatment of diverse disease conditions raises concerns about patient safety, given that much…”
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The contribution of Ghanaian patients to the reporting of adverse drug reactions: a quantitative and qualitative study
Published in BMC public health (18-12-2018)“…Under-reporting of adverse drug reactions (ADRs) is a major challenge for pharmacovigilance in Africa. This study sets out to assess the level of awareness of…”
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Active Safety Surveillance in Africa: Pragmatism and Agility
Published in Drug safety (01-08-2018)“…[1] reports on an active follow-up study to establish the burden of adverse drug reactions (ADRs) due to artemisinin-based antimalarial treatment in selected…”
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Pre-Exposure Prophylaxis for HIV Prevention: Safety Concerns
Published in Drug safety (01-04-2017)“…Available evidence supports the efficacy of pre-exposure prophylaxis (PrEP) in decreasing the incidence of human immunodeficiency virus (HIV) infection among…”
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Prescribing patterns and compliance with World Health Organization recommendations for the management of severe malaria: a modified cohort event monitoring study in public health facilities in Ghana and Uganda
Published in Malaria journal (08-02-2019)“…Injectable artesunate (AS) is the World Health Organization (WHO) recommended medication for the treatment of severe malaria followed with an oral…”
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Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?
Published in BMC medical genetics (14-07-2010)“…Ivermectin, a substrate of multidrug resistance (MDR1) gene and cytochrome P450 (CYP) 3A4, has been used successfully in the treatment of onchocerciasis in…”
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Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population
Published in BMC genetics (02-12-2009)“…Genetic influences on drug efficacy and tolerability are now widely known. Pharmacogenetics has thus become an expanding field with great potential for…”
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Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy
Published in Malaria journal (05-01-2009)“…Change of first-line treatment of uncomplicated malaria to artemisinin-combination therapy (ACT) is widespread in Africa. To expand knowledge of safety…”
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Tenofovir-associated renal toxicity in a cohort of HIV infected patients in Ghana
Published in BMC research notes (22-07-2019)“…Tenofovir disoproxil fumarate (TDF) is a nucleotide analogue recommended in international HIV treatment guidelines. Purpose of this study was to estimate the…”
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Profile of Adverse Events in Patients Receiving Treatment for Malaria in Urban Ghana: A Cohort-Event Monitoring Study
Published in Drug safety (01-06-2014)“…Background Antimalarial treatment strategies have changed much in the last 15 years, resulting in an increased variety of medicines available. Active…”
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Safety Experience During Real-World Use of Injectable Artesunate in Public Health Facilities in Ghana and Uganda: Outcomes of a Modified Cohort Event Monitoring Study (CEMISA)
Published in Drug safety (01-09-2018)“…Introduction Injectable artesunate (Inj AS) is the World Health Organization (WHO)-recommended product for treating severe malaria. However, despite widespread…”
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Association Between the Occurrence of Adverse Drug Events and Modification of First-Line Highly Active Antiretroviral Therapy in Ghanaian HIV Patients
Published in Drug safety (01-11-2016)“…Introduction Patients initiated on highly active antiretroviral therapy (HAART) generally remain on medication indefinitely. A modification in the HAART…”
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Contributions and challenges for worldwide vaccine safety: The Global Advisory Committee on Vaccine Safety at 15 years
Published in Vaccine (17-06-2016)“…Abstract In 1999, the Global Advisory Committee on Vaccine Safety (GACVS) was established by the World Health Organization (WHO) to provide independent…”
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Experiences and Lessons From Implementing Cohort Event Monitoring Programmes for Antimalarials in Four African Countries: Results of a Questionnaire-Based Survey
Published in Drug safety (01-11-2015)“…Introduction Cohort event monitoring (CEM) is an intensive method of post-marketing surveillance for medicines safety. The method is based on prescription…”
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Feasibility and cost of using mobile phones for capturing drug safety information in peri-urban settlement in Ghana: a prospective cohort study of patients with uncomplicated malaria
Published in Malaria journal (19-10-2015)“…The growing need to capture data on health and health events using faster and efficient means to enable prompt evidence-based decision-making is making the use…”
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Pharmacokinetic profile of amodiaquine and its active metabolite desethylamodiaquine in Ghanaian patients with uncomplicated falciparum malaria
Published in Malaria journal (06-01-2021)“…Accurate measurement of anti-malarial drug concentrations in therapeutic efficacy studies is essential to distinguish between inadequate drug exposure and…”
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Factors that influence the intention to use mobile phone caller tunes for patient reporting of adverse drug reactions: a qualitative study
Published in Therapeutic advances in drug safety (2019)“…Patient reporting of adverse drug reactions (ADRs) is low in low- and middle-income countries, in part because of poor awareness to report. With the increase…”
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The Global Vaccine Safety Initiative: enhancing vaccine pharmacovigilance capacity at country level
Published in Bulletin of the World Health Organization (01-09-2014)“…Large-scale immunization programmes now extend to all parts of the world, including least developed countries, where they reach unprecedented numbers of…”
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The ISoP CommSIG for Improving Medicinal Product Risk Communication: A New Special Interest Group of the International Society of Pharmacovigilance
Published in Drug safety (01-07-2015)“…Communicating to patients and healthcare providers about the risks of harm with medicines and how to use medicines safely is vital to pharmacovigilance for…”
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