Search Results - "DOBSON, M. C"

The structural basis of protein folding and its links with human disease by Dobson, C. M., Ellis, R. J., Fersht, A. R., Dobson, Christopher M.

“…The ability of proteins to fold to their functional states following synthesis in the intracellular environment is one of the most remarkable features of…”
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Real-time PCR detection of bacteria belonging to the Firmicutes Phylum by Haakensen, M., Dobson, C.M., Deneer, H., Ziola, B.

“…Members of the bacterial Phylum Firmicutes occupy a wide range of habitats and can be either beneficial or detrimental in diverse settings, including food- and…”
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Structural Characteristics of α-Synuclein Oligomers by Cremades, N, Chen, S W, Dobson, C M

“…Oligomeric forms of amyloid aggregates have been detected in the brains and tissues of patients suffering from neurodegenerative disorders such as Parkinson's…”
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Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy by BOUCHARD, MARIO, ZURDO, JESÚS, NETTLETON, EWAN J., DOBSON, CHRISTOPHER M., ROBINSON, CAROL V.

“…Fourier transform infrared spectroscopy (FTIR), circular dichroism (CD), and electron microscopy (EM) have been used simultaneously to follow the…”
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A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme by Dobson, Christopher M, Dumoulin, Mireille, Last, Alexander M, Desmyter, Aline, Decanniere, Klaas, Canet, Denis, Larsson, Göran, Spencer, Andrew, Archer, David B, Sasse, Jurgen, Muyldermans, Serge, Wyns, Lode, Redfield, Christina, Matagne, André, Robinson, Carol V

“…Amyloid diseases are characterized by an aberrant assembly of a specific protein or protein fragment into fibrils and plaques that are deposited in various…”
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Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the β-domain by Krebs, Mark R.H, Wilkins, Deborah K, Chung, Evonne W, Pitkeathly, Maureen C, Chamberlain, Aaron K, Zurdo, Jesus, Robinson, Carol V, Dobson, Christopher M

“…Wild-type hen lysozyme has been converted from its soluble native state into highly organized amyloid fibrils. In order to achieve this conversion, conditions…”
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Dependence on solution conditions of aggregation and amyloid formation by an SH3 domain by Zurdo, Jesús, Guijarro, J.I, Jiménez, Jose L, Saibil, Helen R, Dobson, Christopher M

“…The formation of amyloid fibrils by the SH3 domain of the α-subunit of bovine phosphatidylinositol-3′-kinase (PI3-SH3) has been investigated under carefully…”
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Preparation and Characterization of Purified Amyloid Fibrils by Zurdo, Jesús, Guijarro, J. Iñaki, Dobson, Christopher M

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Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis by Booth, David R, Sunde, Margaret, Bellotti, Vittorio, Robinson, Carol V, Hutchinson, Winston L, Fraser, Paul E, Hawkins, Philip N, Dobson, Christopher M, Radford, Sheena E, Blake, Colin C. F, Pepys, Mark B

“…Tissue deposition of soluble proteins as amyloid fibrils underlies a range of fatal diseases. The two naturally occurring human lysozyme variants are both…”
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Protein folding and misfolding by Dobson, Christopher M

“…The manner in which a newly synthesized chain of amino acids transforms itself into a perfectly folded protein depends both on the intrinsic properties of the…”
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SAR-based land cover classification of Kuwait by Kwarteng, A. Y., Dobson, M. C., Kellndorfer, J., Williams, R.

“…Orbital synthetic aperture radar (SAR) C-band data acquired by ERS-1/2 in vv-polarization and Radarsat in hh-polarization during the period from 1996 to 1999…”
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Dielectric properties of soils in the 0.3-1.3-GHz range by Peplinski, N.R., Ulaby, F.T., Dobson, M.C.

“…In 1985, the authors reported the development of a semiempirical dielectric model for soils, covering the frequency range between 1.4 and 18 GHz. The model…”
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The folding process of hen lysozyme: a perspective from the 'new view' by Matagne, A, Dobson, C.M

“…How a conformationally disordered polypeptide chain rapidly and efficiently achieves its well-defined native structure is still a major question in modern…”
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Sensitivity to soil moisture by active and passive microwave sensors by Du, Y., Ulaby, F.T., Dobson, M.C.

“…The backscatter measured by radar and the emission measured by a radiometer are both very sensitive to the moisture content m/sub /spl upsi// of bare-soil…”
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Phylogenetic analysis of the genus Pediococcus, including Pediococcus claussenii sp. nov., a novel lactic acid bacterium isolated from beer by Dobson, C. M, Deneer, H, Lee, S, Hemmingsen, S, Glaze, S, Ziola, B

“…C. M. Dobson, H. Deneer, S. Lee, S. Hemmingsen, S. Glaze and B. Ziola Department of Microbiology and Immunology, University of Saskatchewan, 107 Wiggins Road,…”
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Protein misfolding, evolution and disease by Dobson, Christopher M.

“…The number of different types of proteins in the human body approaches 100 000. Proteins are engaged in promoting or controlling virtually every event on which…”
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Detection of Transient Protein Folding Populations by Mass Spectrometry by Miranker, Andrew, Robinson, Carol V., Radford, Sheena E., Aplin, Robin T., Dobson, Christopher M.

“…Hydrogen-deuterium exchange measurements are becoming increasingly important in studies of the dynamics of protein molecules and, particularly, of their…”
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Protein solubility and protein homeostasis: a generic view of protein misfolding disorders by Vendruscolo, Michele, Knowles, Tuomas P J, Dobson, Christopher M

“…According to the "generic view" of protein aggregation, the ability to self-assemble into stable and highly organized structures such as amyloid fibrils is not…”
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Protein engineering as a strategy to avoid formation of amyloid fibrils by VILLEGAS, VIRTUDES, ZURDO, JESÚS, FILIMONOV, VLADIMIR V., AVILÉS, FRANCESC X., DOBSON, CHRISTOPHER M., SERRANO, LUIS

“…The activation domain of human procarboxypeptidase A2 (ADA2h) aggregates following thermal or chemical denaturation at acidic pH. The aggregated material…”
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Exacerbation of psoriasis by thalidomide in Behçet's syndrome by Dobson, C.M., Parslew, R.A.

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