Search Results - "DOAN, Anke"

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  1. 1
    In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent leflunomide to its active α-cyanoenol metabolite A771726: Mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

    In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent leflunomide to its active α-cyanoenol metabolite A771726: Mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes by KALGUTKAR, Amit S, NGUYEN, Hang T, VAZ, Alfin D. N, DOAN, Anke, DALVIE, Deepak K, MCLEOD, Dale G, MURRAY, John C

    Published in Drug metabolism and disposition (01-10-2003)
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  2. 2
    In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

    In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes by Kalgutkar, Amit S, Nguyen, Hang T, Vaz, Alfin D N, Doan, Anke, Dalvie, Deepak K, McLeod, Dale G, Murray, John C

    Published in Drug metabolism and disposition (01-10-2003)
    “…The 3-unsubstituted isoxazole ring in the anti-inflammatory drug leflunomide undergoes a unique N-O bond cleavage to the active alpha-cyanoenol metabolite…”
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    IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES

    IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES by Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod, John C. Murray

    Published in Drug metabolism and disposition (01-10-2003)
    “…The 3-unsubstituted isoxazole ring in the anti-inflammatory drug leflunomide undergoes a unique N–O bond cleavage to the active α-cyanoenol metabolite…”
    Get full text
    Journal Article
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