Search Results - "DIVANGAHI, M"

Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor‐derived extracellular vesicles by Chennakrishnaiah, S., Meehan, B., D'Asti, E., Montermini, L., Lee, T‐H., Karatzas, N., Buchanan, M., Tawil, N., Choi, D., Divangahi, M., Basik, M., Rak, J.

“…Essentials Tumor‐bearing mice were employed to follow oncogenic HRAS sequences in plasma, and blood cells. Cancer DNA accumulated in leukocytes above levels…”
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Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis by Behar, S M, Martin, C J, Booty, M G, Nishimura, T, Zhao, X, Gan, H-X, Divangahi, M, Remold, H G

“…Two different forms of death are commonly observed when Mycobacterium tuberculosis ( Mtb )-infected macrophages die: (i) necrosis, a death modality defined by…”
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Bcl-x L mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages by Zhao, X, Khan, N, Gan, H, Tzelepis, F, Nishimura, T, Park, S-Y, Divangahi, M, Remold, H G

“…Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate…”
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Increased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea by KIMOFF, R. J, HAMID, Q, DIVANGAHI, M, HUSSAIN, S, BAO, W, NAOR, N, PAYNE, R. J, ARIYARAJAH, A, MULRAIN, K, PETROF, B. J

“…Inflammation may contribute to upper airway pathophysiology in obstructive sleep apnoea (OSA). Our objective was to compare upper airway pro-inflammatory…”
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Intestinal helminth infection impacts the systemic distribution and function of the naive lymphocyte pool by King, I L, Mohrs, K, Meli, A P, Downey, J, Lanthier, P, Tzelepis, F, Fritz, J H, Tumanov, A V, Divangahi, M, Leadbetter, E A, Mohrs, M

“…Homeostasis is a fundamental principle of biological systems. A paradigm of immune homeostasis is the remarkably constant number of naive T and B lymphocytes…”
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Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages by Zhao, X, Khan, N, Gan, H, Tzelepis, F, Nishimura, T, Park, S-Y, Divangahi, M, Remold, H G

“…Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate…”
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A73 BEYOND CIGARETTE SMOKE IN COPD: Prostaglandin E2 Attenuates Cigarette Smoke-Induced Cellular Inflammation In A Socs3-Independent Manner by Stampfli, M R, Thayaparan, D, Roos, A, Divangahi, M, Beaulieu, A J

“…Here, we used a well-characterized murine model of cigarette smoke (CS)-induced inflammation and bacterial exacerbation to investigate the mechanism of…”
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NK cell recruitment limits tissue damage during an enteric helminth infection by Gentile, Maria E., Li, Yue, Robertson, Amicha, Shah, Kathleen, Fontes, Ghislaine, Kaufmann, Eva, Polese, Barbara, Khan, Nargis, Parisien, Marc, Munter, Hans M., Mandl, Judith N., Diatchenko, Luda, Divangahi, Maziar, King, Irah L.

“…Parasitic helminths cause significant damage as they migrate through host tissues to complete their life cycle. While chronic helminth infections are…”
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B106 CELLULAR/MOLECULAR MECHANISMS AND TRANSLATIONAL ASPECTS OF RESPIRATORY TRACT INFECTIONS: Ripk3 Regulates Type I Ifn Mediated Immunity To Pulmonary Influenza A Virus Infection by Downey, J, Pernet, E, Coulombe, F, Allard, B, Jaworska, J, Qureshi, S, Martin, J G, Joubert, P, Divangahi, M

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C16 IMMUNITY PATHWAYS IN THE LUNG: Nlrx1 Prevents Mitochondrial Damage And Enhances Macrophage Anti-Viral Immunity By Binding To Influenza Virus Pb1-F2 Protein by Jaworska, J, Coulombe, F, Downey, J, Rousseau, S, Girardin, S, Divangahi, M

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B33 ANTIOXIDANTS, VITAMINS AND RELATED PATHWAYS IN AIRWAYS DISEASE: Airway Adaptation In A Murine Model Of Irritant-Induced Asthma Is Dependent On The Foxp3 Pathway But Not On Regulatory T Cells by Allard, B, Farahnak, S, Panariti, A, Downey, J, McGovern, T, Ano, S, Kaufman, G, Mazer, B, Powell, W, Divangahi, M, Martin, J G

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Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats by Hussain, Sabah N A, Matar, Ghassan, Barreiro, Esther, Florian, Maria, Divangahi, Maziar, Vassilakopoulos, Theodoros

“…Although 4-hydroxy-2-nonenal (HNE, a product of lipid peroxidation) is a major cause of oxidative damage inside skeletal muscles, the exact proteins modified…”
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Differential Cytokine Gene Expression in the Diaphragm in Response to Strenuous Resistive Breathing by Vassilakopoulos, Theodoros, Divangahi, Maziar, Rallis, George, Kishta, Osama, Petrof, Basil, Comtois, Alain, Hussain, Sabah N. A

“…Strenuous resistive breathing induces plasma cytokines that do not originate from circulating monocytes. We hypothesized that cytokine production is induced…”
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Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer by Santosuosso, Michael, Divangahi, Maziar, Zganiacz, Anna, Xing, Zhou

“…Granulocytopenia is thought to be the sole mechanism underlying the increased susceptibility to bacterial infection in hosts with anticancer chemotherapy…”
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IL-12-independent Th1-type immune responses to respiratory viral infection: requirement of IL-18 for IFN-gamma release in the lung but not for the differentiation of viral-reactive Th1-type lymphocytes by Xing, Z, Zganiacz, A, Wang, J, Divangahi, M, Nawaz, F

“…We demonstrated that IL-12 was induced during primary or secondary pulmonary adenoviral infection in wild-type (wt) mice. However, cellular responses were not…”
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Preferential Diaphragmatic Weakness during Sustained Pseudomonas aeruginosa Lung Infection by Divangahi, Maziar, Matecki, Stefan, Dudley, Roy W. R, Tuck, Stephanie A, Bao, Weisheng, Radzioch, Danuta, Comtois, Alain S, Petrof, Basil J

“…Infection with Pseudomonas aeruginosa plays a major role in the pulmonary inflammation and injury associated with cystic fibrosis. Lung inflammation may also…”
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Expression and Regulation of CC Class Chemokines in the Dystrophic (mdx) Diaphragm by Demoule, Alexandre, Divangahi, Maziar, Danialou, Gawiyou, Gvozdic, Dusanka, Larkin, Gary, Bao, Weisheng, Petrof, Basil J

“…In the murine (mdx) model of Duchenne muscular dystrophy, dystrophic changes are much more severe in the diaphragm than in limb muscles, and the diaphragm more…”
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Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes by Matecki, Stefan, Dudley, Roy W R, Divangahi, Maziar, Gilbert, Renald, Nalbantoglu, Josephine, Karpati, George, Petrof, Basil J

“…Duchenne muscular dystrophy is caused by defects in the dystrophin gene, and the mdx mouse is the most frequently employed genetic model of this disease. It is…”
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