Search Results - "DISTLER, G"

Systematic benchmarking of omics computational tools by Mangul, Serghei, Martin, Lana S., Hill, Brian L., Lam, Angela Ka-Mei, Distler, Margaret G., Zelikovsky, Alex, Eskin, Eleazar, Flint, Jonathan

“…Computational omics methods packaged as software have become essential to modern biological research. The increasing dependence of scientists on these powerful…”
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Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights by Distler, Margaret G, Palmer, Abraham A

“…Glyoxalase 1 (GLO1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis that…”
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Genome wide association analysis in a mouse advanced intercross line by Gonzales, Natalia M., Seo, Jungkyun, Hernandez Cordero, Ana I., St. Pierre, Celine L., Gregory, Jennifer S., Distler, Margaret G., Abney, Mark, Canzar, Stefan, Lionikas, Arimantas, Palmer, Abraham A.

“…The LG/J x SM/J advanced intercross line of mice (LG x SM AIL) is a multigenerational outbred population. High minor allele frequencies, a simple genetic…”
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Right lateral orbitofrontal cortex inhibitory transcranial magnetic stimulation for treatment of refractory mood and depression by Tadayonnejad, Reza, Citrenbaum, Cole, Ngo, Thuc Doan P., Corlier, Juliana, Wilke, Scott A., Slan, Aaron, Distler, Margaret G., Hoftman, Gil, Adelekun, Adesewa E., Leuchter, Michael K., Koek, Ralph J., Ginder, Nathaniel D., Krantz, David, Artin, Hewa, Strouse, Thomas, Bari, Ausaf A., Leuchter, Andrew F.

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A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior by Williams, 4th, Richard, Lim, Jackie E, Harr, Bettina, Wing, Claudia, Walters, Ryan, Distler, Margaret G, Teschke, Meike, Wu, Chunlei, Wiltshire, Tim, Su, Andrew I, Sokoloff, Greta, Tarantino, Lisa M, Borevitz, Justin O, Palmer, Abraham A

“…Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays…”
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Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility by Distler, Margaret G., Gorfinkle, Naomi, Papale, Ligia A., Wuenschell, Gerald E., Termini, John, Escayg, Andrew, Winawer, Melodie R., Palmer, Abraham A.

“…Summary Purpose Epilepsy is a complex disease characterized by a predisposition toward seizures. There are numerous barriers to the successful treatment of…”
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Exercise Predicts a Good Night's Sleep: Preliminary Findings from a UCLA Study of First-Episode Schizophrenia by Subotnik, Kenneth L, McEwen, Sarah C, Ventura, Joseph, Turner, Luana Rene, Sturdevant, Yurika, Niess, Trudy L, Casaus, Laurie R, Distler, Margaret G, Zito, Michael F, Hellemann, Gerhard S, Nguyen, Clara D, Nuechterlein, Keith H

“…Physical exercise can improve sleep quality in the general population. Understanding the negative impact of poor sleep quality on multiple domains of…”
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Driving performance and psychomotor function in depressed patients treated with agomelatine or venlafaxine by Brunnauer, A, Buschert, V, Fric, M, Distler, G, Sander, K, Segmiller, F, Zwanzger, P, Laux, G

“…We conducted a randomized case-control study in depressive inpatients to assess the effects of agomelatine and venlafaxine on psychomotor functions related to…”
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Assessment of behaviors modeling aspects of schizophrenia in Csmd1 mutant mice by Distler, Margaret G, Opal, Mark D, Dulawa, Stephanie C, Palmer, Abraham A

“…Schizophrenia is a debilitating psychotic disorder that affects up to 1.5% of the population worldwide. Two recent studies in humans identified genome-wide…”
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Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development by McMurray, Katherine M J, Distler, Margaret G, Sidhu, Preetpal S, Cook, James M, Arnold, Leggy A, Palmer, Abraham A, Plant, Leigh D

“…Many current pharmacological treatments for neuropsychiatric disorders, such as anxiety and depression, are limited by a delayed onset of therapeutic effect,…”
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Modulation of Tcf7l2 Expression Alters Behavior in Mice by Savic, Daniel, Distler, Margaret G, Sokoloff, Greta, Shanahan, Nancy A, Dulawa, Stephanie C, Palmer, Abraham A, Nobrega, Marcelo A

“…The comorbidity of type 2 diabetes (T2D) with several psychiatric diseases is well established. While environmental factors may partially account for these…”
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A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine by Bryant, Camron D., Graham, Melissa E., Distler, Margaret G., Munoz, Michaelanne B., Li, Dongdong, Vezina, Paul, Sokoloff, Greta, Palmer, Abraham A.

“…Rationale We previously colocalized a quantitative trait locus (QTL) for sensitivity to the locomotor stimulant effects of methamphetamine (MA) with a QTL for…”
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The influence of smoking on the serum level of duloxetine by Fric, M, Pfuhlmann, B, Laux, G, Riederer, P, Distler, G, Artmann, S, Wohlschläger, M, Liebmann, M, Deckert, J

“…Duloxetine is a dual acting antidepressant (selective serotonin and norepinephrine reuptake inhibitor). Existing data suggest that the advisable therapeutic…”
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EPA-0974 – Driving performance and psychomotor function in depressed patients treated with agomelatine or venlafaxine by Brunnauer, A, Distler, G, Fric, M, Buschert, V, Sander, K, Segmiller, F, Kosilek, R, Laux, G

“…Objective The aim of the study was to investigate the influence of agomelatine and venlafaxine on driving skills and on driving performance in an on-road…”
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Brain circuitry underlying the ABC model of anxiety by Bystritsky, Alexander, Spivak, Norman M., Dang, Bianca H., Becerra, Sergio A., Distler, Margaret G., Jordan, Sheldon E., Kuhn, Taylor P.

“…Anxiety Disorders are prevalent and often chronic, recurrent conditions that reduce quality of life. The first-line treatments, such as serotonin reuptake…”
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Safety and efficacy of targeting the supplementary motor area with double-cone deep transcranial magnetic stimulation vs figure-eight coil in treatment of obsessive-compulsive disorder with comorbid major depressive disorder by Tadayonnejad, Reza, Corlier, Juliana, Valles, Thomas E., Citrenbaum, Cole, Matthews, Cole, Einstein, Evan, Wilke, Scott A., Slan, Aaron, Distler, Margaret G., Hoftman, Gil, Adelekun, Adesewa E., Oughli, Hanadi A., Leuchter, Michael K., Artin, Hewa, Koek, Ralph J., Ginder, Nathaniel D., Krantz, David, Strouse, Thomas, Leuchter, Andrew F.

“…The Supplementary Motor Area (SMA), a relatively large brain structure predominantly located along the interhemispheric fissure, is an established target for…”
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A comprehensive benchmarking of WGS-based deletion structural variant callers by Sarwal, Varuni, Niehus, Sebastian, Ayyala, Ram, Kim, Minyoung, Sarkar, Aditya, Chang, Sei, Lu, Angela, Rajkumar, Neha, Darfci-Maher, Nicholas, Littman, Russell, Chhugani, Karishma, Soylev, Arda, Comarova, Zoia, Wesel, Emily, Castellanos, Jacqueline, Chikka, Rahul, Distler, Margaret G, Eskin, Eleazar, Flint, Jonathan, Mangul, Serghei

“…Abstract Advances in whole-genome sequencing (WGS) promise to enable the accurate and comprehensive structural variant (SV) discovery. Dissecting SVs from WGS…”
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The role of sex and age in the differential efficacy of 10 Hz and intermittent theta-burst (iTBS) repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD) by Slan, Aaron R., Citrenbaum, Cole, Corlier, Juliana, Ngo, Doan, Vince-Cruz, Nikita, Jackson, Nicholas J., Valles, Thomas E., Wilke, Scott A., Hoftman, Gil D., Koek, Ralph J., Leuchter, Michael K., Krantz, David E., Strouse, Thomas B., Tadayonnejad, Reza, Ginder, Nathaniel D., Distler, Margaret G., Lee, John H., Adelekun, Adesewa E., Einstein, Evan H., Oughli, Hanadi A., Leuchter, Andrew F.

“…Sex- and age-dependent outcome differences have been observed in treatment of Major Depressive Disorder (MDD), including 10 Hz repetitive Transcranial Magnetic…”
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General methods for the determination of the stiffness tensor and mass density of thin films using brillouin light scattering: Study of tungsten carbide films by WITTKOWSKI, T, DISTLER, G, JUNG, K, HILLEBRANDS, B, COMINS, J. D

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Synaptic connections between identified neuron types in the antennal lobe glomeruli of the cockroach, Periplaneta americana: II. local multiglomerular interneurons by Distler, Paul G., Boeckh, Jürgen

“…Synapses between three types of antennal lobe neurons, namely, local multiglomerular interneurons, antennal receptor neurons, and γ‐aminobutyric acid…”
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