Search Results - "DIRIONG, S"
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Evolution of the Glx-tRNA Synthetase Family: The Glutaminyl Enzyme as a Case of Horizontal Gene Transfer
Published in Proceedings of the National Academy of Sciences - PNAS (30-08-1994)“…An important step ensuring the fidelity in protein biosynthesis is the aminoacylation of tRNAs by aminoacyl-tRNA synthetases. The accuracy of this process…”
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Localization of Staf50, a member of the ring finger family, to 11p15 by fluorescence in situ hybridization
Published in Genomics (San Diego, Calif.) (15-05-1996)“…The interferons (IFNs) are a family of secreted multifunctional proteins. First characterized for their antiviral functions, it has now been established that…”
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Localization of the ribonuclease L inhibitor gene (RNSAI), a new member of the interferon-regulated 2-5A pathway, to 4q31 by fluorescence in situ hybridization
Published in Genomics (San Diego, Calif.) (15-03-1996)“…The 2-5A/RNase L system is one of the major pathways induced by interferon (IFN). It plays a major role in the antiviral and antiproliferative activities of…”
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Chromosomal localization of the human genes for α1A, α1B, and α1E voltage-dependent Ca2+ channel subunits
Published in Genomics (San Diego, Calif.) (01-12-1995)Get full text
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The Human Rho-GEF Trio and Its Target GTPase RhoG Are Involved in the NGF Pathway, Leading to Neurite Outgrowth
Published in Current biology (19-02-2002)“…Rho-GTPases control a wide range of physiological processes by regulating actin cytoskeleton dynamics [1]. Numerous studies on neuronal cell lines have…”
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Identification of the first Rho–GEF inhibitor, TRIPα, which targets the RhoA-specific GEF domain of Trio
Published in FEBS letters (17-07-2002)“…The Rho–guanine nucleotide exchange factors (Rho–GEFs) remodel the actin cytoskeleton via their Rho–GTPase targets and affect numerous physiological processes…”
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Assignment of the human 8.5 H gene to chromosome 5, region 5q35
Published in Human genetics (01-06-1994)“…The human 8.5 H probe was isolated from a human cerebellum cDNA library with a probe corresponding to the coding region of the murine 8.5 M cDNA. This cDNA…”
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The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the Rhoa pathways in vivo
Published in Oncogene (15-01-1998)“…Trio contains two functional guanine nucleotide exchange factors (GEF) domains for the Rho-like GTPases and a serine/threonine kinase domain. In vitro, GEF…”
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A new hybrid cell line containing only human chromosome 15 selected through fluorescence in situ hybridization and characterized by Alu-PCR amplification of the human DNA
Published in Annales de génétique (1995)“…Human Cot1 DNA directly labeled with dUTP-fluorochromes (FITC, Rhodamin) and used as a probe, allowed rapid detection of one or a few human chromosomes in…”
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The Human Rho-GEF Trio and Its Target GTPase RhoG Are Involved in the NGF Pathway, Leading to Neurite Outgrowth
Published in Current biology (19-02-2002)“…Rho-GTPases control a wide range of physiological processes by regulating actin cytoskeleton dynamics. Numerous studies on neuronal cell lines have established…”
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EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments
Published in Genomics (San Diego, Calif.) (20-03-1995)“…Proteins with seven transmembrane segments (7TM) define a superfamily of receptors (7TM receptors) sharing the same topology: an extracellular N-terminus,…”
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Human Cardiac Troponin T: Cloning and Expression of New Isoforms in the Normal and Failing Heart
Published in Circulation research (01-04-1995)“…Troponin T, like many myofibrillar proteins, exists as multiple isoforms encoded by distinct genes or generated by splicing of the same primary RNA transcript…”
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Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits
Published in Genomics (San Diego, Calif.) (10-12-1995)“…The alpha 1 subunit genes encoding voltage-dependent Ca2+ channels are members of a gene family. We have used human brain cDNA probes to localize the neuronal…”
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Isolation and Regional Mapping of cDNAs Expressed during Early Human Development
Published in Genomics (San Diego, Calif.) (01-01-1997)“…A cDNA sequencing project was initiated with the aim of isolating and mapping new genes expressed during early human development. A human embryo cDNA library…”
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Direct selection of cDNAs using whole chromosomes
Published in Nucleic acids research (11-11-1995)“…We have developed a method for direct selection of cDNAs using whole chromosomes as target DNA. Double-strand cDNAs were synthesized from human fetal brain…”
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Structural Organization and Chromosomal Localization of a Human Gene (HIP/PAP) Encoding a C‐type Lectin Overexpressed in Primary Liver Cancer
Published in European journal of biochemistry (15-08-1994)“…We previously identified, through differential screening of a human primary liver cancer library, a novel gene (named HIP)the expression of which is markedly…”
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Role of the multifunctional Trio protein in the control of the Rac1 and RhoA gtpase signaling pathways
Published in Comptes rendus des seances de la Societe de biologie et de ses filiales (1998)“…The small GTPases Cdc42, Rac and RhoA have important regulatory roles in mediating cytoskeletal rearrangements, MAP kinase cascades and induction of G1 cell…”
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