Search Results - "DIORIO, J. P."

Coexisting dysfibrinogenemia (gammaR275C) and factor V Leiden deficiency associated with thromboembolic disease (fibrinogen Cedar Rapids) by Siebenlist, K R, Mosesson, M W, Meh, D A, DiOrio, J P, Albrecht, R M, Olson, J D

“…Fibrinogen Cedar Rapids is a heterozygous dysfibrinogenemia (gammaR275C) that was associated with thromboembolism during and following pregnancy in three…”
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Disintegration and reorganization of fibrin networks during tissue-type plasminogen activator-induced clot lysis by Meh, D A, Mosesson, M W, DiOrio, J P, Siebenlist, K R, Hernandez, I, Amrani, D L, Stojanovich, L

“…In this study, we investigated tissue-type plasminogen activator (tPA)-induced lysis of glutamic acid (glu)-plasminogen-containing or lysine…”
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Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin‐binding γ′ chain sequence by MOSESSON, M. W., COOLEY, B. C., HERNANDEZ, I., DIORIO, J. P., WEILER, H.

“…Background and objectives: Thrombin binding activity in murine fibrin (Antithrombin I) is restricted to its E domains inasmuch as murine γ′ chains (mu‐γ′) do…”
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Evidence for a Second Type of Fibril Branch Point in Fibrin Polymer Networks, the Trimolecular Junction by Mosesson, Michael W., DiOrio, James P., Siebenlist, Kevin R., Wall, Joseph S., Hainfeld, James F.

“…Fibrin molecules polymerize to double-stranded fibrils by intermolecular end-to-middle domain pairing of complementary polymerization sites, accompanied by…”
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Identification of Covalently Linked Trimeric and Tetrameric D Domains in Crosslinked Fibrin by Mosesson, Michael W., Siebenlist, Kevin R., Amrani, David L., DiOrio, James P.

“…Following proteolytic conversion of fibrinogen to fibrin, clot assembly commences with formation of double-stranded fibrils that subsequently branch…”
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The role of fibrinogen D domain intermolecular association sites in the polymerization of fibrin and fibrinogen Tokyo II (gamma 275 Arg-->Cys) by Mosesson, M W, Siebenlist, K R, DiOrio, J P, Matsuda, M, Hainfeld, J F, Wall, J S

“…Intermolecular end-to-middle domain pairing between a thrombin-exposed 'A' polymerization site in the central 'E' domain of fibrin, and a constitutive…”
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Molecular basis for fibrinogen Dusart (Aα 554 Arg → Cys) and its association with abnormal fibrin polymerization and thrombophilia by KOOPMAN, J, HAVERKATE, F, CAEN, J. P, GRIMBERGEN, J, LORD, S. T, MOSESSON, M. W, DIORIO, J. P, SIEBENLIST, K. S, LEGRAND, C, SORIA, J, SORIA, C

“…The molecular defect in the abnormal fibrinogen Dusart (Paris V) that is associated with thrombophilia was determined by sequence analysis of genomic DNA that…”
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The polymerization and thrombin-binding properties of des-(B beta 1-42)-fibrin by Siebenlist, K R, DiOrio, J P, Budzynski, A Z, Mosesson, M W

“…Multiple factors affect the thrombin-catalyzed conversion of fibrinogen to fibrin, including: fibrinopeptide (FPA and FPB) release leading to exposure of two…”
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Studies on the Ultrastructure of Fibrin Lacking Fibrinopeptide B (β-Fibrin) by Mosesson, M.W., DiOrio, J.P., Müller, M.F., Shainoff, J.R., Siebenlist, K.R., Amrani, D.L., Homandberg, G.A., Soria, J., Soria, C., Samama, M.

“…Release of fibrinopeptide B from fibrinogen by copperhead venom procoagulant enzyme results in a form of fibrin (β-fibrin) with weaker self-aggregation…”
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Wound healing. Role of commercial fibrin sealants by Amrani, D L, Diorio, J P, Delmotte, Y

“…This paper focuses on the use of commercial fibrin sealant (FS) in specific wound healing applications. This review is not intended to be all inclusive, but to…”
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The ultrastructure of fibrinogen-420 and the fibrin-420 clot by Mosesson, M.W., DiOrio, J.P., Hernandez, I., Hainfeld, J.F., Wall, J.S., Grieninger, G.

“…Fibrinogen-420 is a minor subclass of human fibrinogen that is so named because of its higher molecular weight compared to fibrinogen-340, the predominant form…”
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Structural model of factors V and Va based on scanning transmission electron microscope images and mass analysis by MOSESSON, M. W, CHURCH, W. R, DIORIO, J. P, SRIRAM KRISHNASWAMY, MANN, K. G, HAINFELD, J. F, WALL, J. S

“…Coagulation factor V (fV) is a single-chain glycoprotein (Mr 330,000; domain structure A1-A2-B-A3-C1-C2) that is activated to factor Va (fVa; Mr 174,000) by…”
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Human plasma fibronectin structure probed by steady-state fluorescence polarization: evidence for a rigid oblate structure by Benecky, Michael J, Kolvenbach, Carl G, Wine, Richard W, DiOrio, James P, Mosesson, Michael W

“…In order to more clearly define the structure of human plasma fibronectin (PFn) under physiologic buffer conditions, we determined the mean harmonic rotational…”
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Structural model of porcine factor VIII and factor VIIIa molecules based on scanning transmission electron microscope (STEM) images and STEM mass analysis by MOSESSON, M. W, FASS, D. N, LOLLAR, P, DIORIO, J. P, PARKER, C. G, KNUTSON, G. J, HAINFELD, J. F, WALL, J. S

“…Porcine plasma factor VIII (fVIII) molecules are heterodimers composed of a 76,000-mol wt light chain (-A3-C1-C2) and a heavy chain ranging in molecular weight…”
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The polymerization of fibrinogen Dusart (A alpha 554 Arg-->Cys) after removal of carboxy terminal regions of the A alpha-chains by Siebenlist, K R, Mosesson, M W, DiOrio, J P, Soria, J, Soria, C, Caen, J P

“…The six polypeptide chains of normal fibrinogen are covalently linked by interchain disulphide bonds, and there are no free sulphydryl groups. Fibrinogen…”
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Affinity purified tetanus toxin binds to isolated chromaffin granules and inhibits catecholamine release in digitonin-permeabilized chromaffin cells by Lazarovici, Philip, Fujita, Ko, Contreras, Margarita L., DiOrio, James P., Lelkes, Peter I.

“…Tetanus toxin, a potent neurotoxin which blocks neurotransmitter release in the CNS, also inhibits Ca 2+-induced catecholamine release from…”
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Fibrinogen Naples I (Bβ A68T) Nonsubstrate Thrombin-Binding Capacities by Meh, David A., Mosesson, Michael W., Siebenlist, Kevin R., Simpson-Haidaris, Patricia J., Brennan, Stephen O., DiOrio, James P., Thompson, Kevin, Di Minno, Giovanni

“…Fibrinogen Naples I (Bβ A68T) is characterized by defective thrombin binding and fibrinopeptide cleavage at the fibrinogen substrate site in the E domain. We…”
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Isolation of germ line-dependent female-sterile mutation that affects yolk specific sequestration and chorion formation in Drosophila by Waring, Gail L., DiOrio, James P., Hennen, Sally

“…Two loci on the X chromosome have been implicated in choriogenesis by in situ hybridization of poly A-containing RNA from choriogenic eggchambers to Drosophila…”
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Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin-binding I3a2 chain sequence by Mosesson, M W, Cooley, B C, Hernandez, I, Diorio, J P, Weiler, H

“…Background and objectives:Thrombin binding activity in murine fibrin (Antithrombin I) is restricted to its E domains inasmuch as murine gamma ' chains (mu-…”
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Fibrinogen Niigata With Impaired Fibrin Assembly: An Inherited Dysfibrinogen With a Bβ Asn-160 to Ser Substitution Associated With Extra Glycosylation at Bβ Asn-158 by Sugo, Teruko, Nakamikawa, Chizuko, Takano, Hiroshi, Mimuro, Jun, Yamaguchi, Shu-ichi, Mosesson, Michael W., Meh, David A., DiOrio, James P., Takahashi, Noriko, Takahashi, Hoyu, Nagai, Koichi, Matsuda, Michio

“…A novel BβAsn-160 (TAA) to Ser (TGA) substitution has been identified in fibrinogen Niigata derived from a 64-year-old asymptomatic woman, who is heterozygotic…”
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