Search Results - "DING, Jane"

ETDB-Caltech: A blockchain-based distributed public database for electron tomography by Ortega, Davi R, Oikonomou, Catherine M, Ding, H Jane, Rees-Lee, Prudence, Jensen, Grant J

“…Three-dimensional electron microscopy techniques like electron tomography provide valuable insights into cellular structures, and present significant…”
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The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation by Ding, Jane, Li, Tai, Wang, Xiangwei, Zhao, Erhu, Choi, Jeong-Hyeon, Yang, Liqun, Zha, Yunhong, Dong, Zheng, Huang, Shuang, Asara, John M., Cui, Hongjuan, Ding, Han-Fei

“…Increased activation of the serine-glycine biosynthetic pathway is an integral part of cancer metabolism that drives macromolecule synthesis needed for cell…”
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Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway by Xia, Yingfeng, Ye, Bingwei, Ding, Jane, Yu, Yajie, Alptekin, Ahmet, Thangaraju, Muthusamy, Prasad, Puttur D, Ding, Zhi-Chun, Park, Eun Jeong, Choi, Jeong-Hyeon, Gao, Bei, Fiehn, Oliver, Yan, Chunhong, Dong, Zheng, Zha, Yunhong, Ding, Han-Fei

“…amplification drives the development of neuronal cancers in children and adults. Given the challenge in therapeutically targeting MYCN directly, we searched…”
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Simulations suggest a constrictive force is required for Gram-negative bacterial cell division by Nguyen, Lam T., Oikonomou, Catherine M., Ding, H. Jane, Kaplan, Mohammed, Yao, Qing, Chang, Yi-Wei, Beeby, Morgan, Jensen, Grant J.

“…To divide, Gram-negative bacterial cells must remodel cell wall at the division site. It remains debated, however, whether this cell wall remodeling alone can…”
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KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism by Zhao, Erhu, Ding, Jane, Xia, Yingfeng, Liu, Mengling, Ye, Bingwei, Choi, Jeong-Hyeon, Yan, Chunhong, Dong, Zheng, Huang, Shuang, Zha, Yunhong, Yang, Liqun, Cui, Hongjuan, Ding, Han-Fei

“…The histone lysine demethylase KDM4C is often overexpressed in cancers primarily through gene amplification. The molecular mechanisms of KDM4C action in…”
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Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells by Wright, Elizabeth R, Schooler, Jordan B, Ding, H Jane, Kieffer, Collin, Fillmore, Christopher, Sundquist, Wesley I, Jensen, Grant J

“…The major structural elements of retroviruses are contained in a single polyprotein, Gag, which in human immunodeficiency virus type 1 (HIV‐1) comprises the…”
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Vagus nerve stimulation does not alter brainstem nuclei morphology in patients with refractory epilepsy by Ding, Jane J., Liu, Peter, Rebernig, Hillary, Suller-Marti, Ana, Parrent, Andrew G., Burneo, Jorge G., Hammond, Robert R., Ang, Lee-Cyn, Zhang, Qi

“…•Neuromodulation is a treatment option for patients with refractory epilepsy.•This is the first histopathological study of the long-term effects of vagus nerve…”
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Therapeutic targeting of both dihydroorotate dehydrogenase and nucleoside transport in MYCN-amplified neuroblastoma by Yu, Yajie, Ding, Jane, Zhu, Shunqin, Alptekin, Ahmet, Dong, Zheng, Yan, Chunhong, Zha, Yunhong, Ding, Han-Fei

“…Metabolic reprogramming is an integral part of the growth-promoting program driven by the MYC family of oncogenes. However, this reprogramming also imposes…”
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Long helical filaments are not seen encircling cells in electron cryotomograms of rod-shaped bacteria by Swulius, Matthew T., Chen, Songye, Jane Ding, H., Li, Zhuo, Briegel, Ariane, Pilhofer, Martin, Tocheva, Elitza I., Lybarger, Suzanne R., Johnson, Tanya L., Sandkvist, Maria, Jensen, Grant J.

“…► No long helical filaments are seen near or along rod-shaped bacterial inner membranes by electron cryo-tomography. ► Electron cryo-tomography has the…”
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Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells by Liu, Mengling, Xia, Yingfeng, Ding, Jane, Ye, Bingwei, Zhao, Erhu, Choi, Jeong-Hyeon, Alptekin, Ahmet, Yan, Chunhong, Dong, Zheng, Huang, Shuang, Yang, Liqun, Cui, Hongjuan, Zha, Yunhong, Ding, Han-Fei

“…High-risk neuroblastoma remains one of the deadliest childhood cancers. Identification of metabolic pathways that drive or maintain high-risk neuroblastoma may…”
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HOXC9 Links Cell-Cycle Exit and Neuronal Differentiation and Is a Prognostic Marker in Neuroblastoma by LING MAO, JANE DING, YUNHONG ZHA, LIQUN YANG, MCCARTHY, Brian A, KING, William, HONGJUAN CUI, DING, Han-Fei

“…Differentiation status in neuroblastoma strongly affects clinical outcomes and inducing differentiation is a treatment strategy in this disease. However, the…”
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The Structure of Isolated Synechococcus Strain WH8102 Carboxysomes as Revealed by Electron Cryotomography by Iancu, Cristina V., Ding, H. Jane, Morris, Dylan M., Dias, D. Prabha, Gonzales, Arlene D., Martino, Anthony, Jensen, Grant J.

“…Carboxysomes are organelle-like polyhedral bodies found in cyanobacteria and many chemoautotrophic bacteria that are thought to facilitate carbon fixation…”
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MYCN Promotes the Expansion of Phox2B-Positive Neuronal Progenitors to Drive Neuroblastoma Development by Alam, Goleeta, Cui, Hongjuan, Shi, Huilin, Yang, Liqun, Ding, Jane, Mao, Ling, Maltese, William A, Ding, Han-Fei

“…Amplification of the oncogene MYCN is a tumorigenic event in the development of a subset of neuroblastomas that commonly consist of undifferentiated or poorly…”
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DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma by Olsen, Thale Kristin, Dyberg, Cecilia, Embaie, Bethel Tesfai, Alchahin, Adele, Milosevic, Jelena, Ding, Jane, Otte, Jörg, Tümmler, Conny, Hed Myrberg, Ida, Westerhout, Ellen M, Koster, Jan, Versteeg, Rogier, Ding, Han-Fei, Kogner, Per, Johnsen, John Inge, Sykes, David B, Baryawno, Ninib

“…Despite intensive therapy, children with high-risk neuroblastoma are at risk of treatment failure. We applied a multiomic system approach to evaluate metabolic…”
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Evaluating the Effectiveness of Using Standard Mammogram Form to Predict Breast Cancer Risk: Case-Control Study by Ding, Jane, Warren, Ruth, Warsi, Iqbal, Day, Nick, Thompson, Deborah, Brady, Michael, Tromans, Christopher, Highnam, Ralph, Easton, Douglas

“…Breast density is a well-known breast cancer risk factor. Most current methods of measuring breast density are area based and subjective. Standard mammogram…”
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Bmi-1 Regulates the Differentiation and Clonogenic Self-renewal of I-type Neuroblastoma Cells in a Concentration-dependent Manner by Cui, Hongjuan, Ma, Jun, Ding, Jane, Li, Tai, Alam, Goleeta, Ding, Han-Fei

“…Human neuroblastoma I-type cells have been proposed as a population of malignant neural crest stem cells, based on their high tumorigenic potential, expression…”
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Loss of Negative Feedback Control of Nuclear Factor-κB2 Activity in Lymphocytes Leads to Fatal Lung Inflammation by Yang, Liqun, Cui, Hongjuan, Wang, Zhe, Zhang, Baochun, Ding, Jane, Liu, Lin, Ding, Han-Fei

“…Proteolytic processing of the nuclear factor (NF)-κB2 precursor protein p100 generates the active NF-κB2 subunit p52, which in turn transcriptionally…”
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NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors by McCarthy, Brian A, Yang, Liqun, Ding, Jane, Ren, Mingqiang, King, William, ElSalanty, Mohammed, Zakhary, Ibrahim, Sharawy, Mohamed, Cui, Hongjuan, Ding, Han-Fei

“…Abnormal NF-κB2 activation has been implicated in the pathogenesis of multiple myeloma, a cancer of plasma cells. However, a causal role for aberrant NF-κB2…”
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Genome-wide analysis of HOXC9-induced neuronal differentiation of neuroblastoma cells by Wang, Xiangwei, Yang, Liqun, Choi, Jeong-Hyeon, Kitamura, Eiko, Chang, Chang-Sheng, Ding, Jane, Lee, Eun J., Cui, Hongjuan, Ding, Han-Fei

“…Induction of differentiation is a therapeutic strategy in neuroblastoma, a common pediatric cancer of the sympathetic nervous system. The homeobox protein…”
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Genomic and proteomic approaches towards an understanding of sleep by O'Hara, Bruce F, Ding, Jane, Bernat, Rebecca L, Franken, Paul

“…The basic functions of sleep are still unclear, however, recent advances in genomics and proteomics have begun to contribute to our understanding of both…”
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