Search Results - "DIMICHELE, L"

THE DETERMINATION OF THE STEREOISOMERS OF A MULTIFUNCTIONAL B-ADRENOCEPTOR AGENT BY CHIRAL DERIVATIZATION AND HPLC by Novak, T. J., DiMichele, L.

“…The reaction of chiral methylbenzyl and napthylethyl isocyanates with a β-adrenoceptor agent having two stereogenic centers and multiple reaction sites was…”
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LCMS using a hybrid quadrupole time of flight mass spectrometer for impurity identification during process chemical development of a novel integrase inhibitor by Novak, T.J., Grinberg, N., Hartman, B., Marcinko, S., DiMichele, L., Mao, B.

“…LCMS incorporating a quadrupole time of flight mass spectrometer was used to identify impurities found in a chemical process development sample of a novel…”
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High aerobic capacities in the skeletal muscles of pinnipeds: adaptations to diving hypoxia by Kanatous, Shane B, DiMichele, Leonard V, Cowan, Daniel F, Davis, Randall W

“…1  Department of Medicine, University of California at San Diego, La Jolla, California, 92092-0623A; 2  Department of Wildlife and Fisheries Science, Texas A…”
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A Practical Synthesis of a COX-2-Specific Inhibitor by Davies, Ian W, Marcoux, Jean-Francois, Corley, Edward G, Journet, Michel, Cai, Dong-Wei, Palucki, Michael, Wu, Jimmy, Larsen, Robert D, Rossen, Kai, Pye, Philip J, DiMichele, Lisa, Dormer, Peter, Reider, Paul J

“…A number of synthetic strategies to the Cox-2 specific inhibitor 1 have been described. These studies have led to the identification of a novel pyridine…”
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Sex estimation in a modern American osteological sample using a discriminant function analysis from the calcaneus by DiMichele, Daniel L, Spradley, M. Katherine

“…Abstract Reliable methods for sex estimation during the development of a biological profile are important to the forensic community in instances when the…”
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PP26 Immune response to gastrin-17 is an independent covariate for improved survival in gastrointestinal cancers by DiMichele, L, Weidman, J, Oortgiesen, J.M

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Transcription-Based Amplification System and Detection of Amplified Human Immunodeficiency Virus Type 1 with a Bead-Based Sandwich Hybridization Format by Kwoh, D. Y., Davis, G. R., Whitfield, K. M., Chappelle, H. L., DiMichele, L. J., Gingeras, T. R.

“…The in vitro amplification of biologically important nucleic acids has proceeded principally by a strategy of DNA replication. Polymerase chain reaction was…”
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Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis : impact on titer, analogue levels, and the identification of new analogues of pneumocandin B0 by PETERSEN, L. A, HUGHES, D. L, HUGHES, R, DIMICHELE, L, SALMON, P, CONNORS, N

“…Addition of the amino acids threonine, serine, proline, and arginine to fermentations of the fungus Glarea lozoyensis influenced both the pneumocandin titer…”
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Geographic variation in development rate between populations of the teleost Fundulus heteroclitus by DIMICHELE, L, WESTERMAN, M. E

“…A study examined the development rates of teleost Fundulus heteroclitus embryos from Florida and Massachusetts. A genetic basis was found to be a possible…”
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Kinetic analysis and subambient temperature on-line on-column derivatization of an active aldehyde by LoBrutto, R, Bereznitski, Y, Novak, T.J, DiMichele, L, Pan, L, Journet, M, Kowal, J, Grinberg, N

“…The chromatographic analysis of aldehydes under typical reversed-phase conditions may be a challenging task due to an equilibrium process leading to the…”
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An efficient asymmetric hydrogenation approach to the synthesis of the Crixivan ® piperazine intermediate by Rossen, K., Pye, P.J., DiMichele, L.M., Volante, R.P., Reider, P.J.

“…The Crixivan ® HIV protease inhibitor piperazine intermediate 2 was prepared by a four step sequence using a chiral hydrogenation of the tetrahydropyrazine 9…”
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PREPARATION, ISOLATION, AND CHARACTERIZATION OF DIMERIC DEGRADATION PRODUCTS OF THE 1β-METHYLCARBAPENEM ANTIBIOTIC, ERTAPENEM by Sajonz, P., Natishan, T. K., Wu, Y., Williams, J. M., Pipik, B., DiMichele, L., Novak, T., Pitzenberger, S., Dubost, D., Almarsson, Ö.

“…Dimeric degradates of ertapenem, a novel broad-spectrum 1β-methyl carbapenem antibiotic currently in development, have been prepared by controlled degradation…”
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An efficient and versatile synthesis of piperazine-2-carboxamides by Rossen, K., Sager, J., DiMichele, L.M.

“…An efficient and versatile synthesis of piperazine-2-carboxamides 5 is described. The preparation consists of a one-pot, 4-component Ugi condensation between…”
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An efficient and stereoselective construction of the core structure of the manzamines via an intramolecular Michael reaction by Brands, K.M.J., DiMichele, L.M.

“…A strategically functionalized tricyclic subunit of the manzamines was efficiently synthesized with complete stereochemical control using a combination of an…”
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An ecological simulation reveals balancing selection acting on development rate in the teleost Fundulus heteroclitus by WILLIAMSON, E. G, DIMICHELE, L

“…A study developed a computer model that simulated the reproductive strategy in Fundulus heteroclitus in order to quantify and clarify the relationship between…”
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Detection of Human Immunodeficiency Virus Type 1 in AIDS Patients Using Amplification-Mediated Hybridization Analyses: Reproducibility and Quantitative Limitations by Davis, G. R., Blumeyer, K., DiMichele, L. J., Whitfield, K. M., Chappelle, H., Riggs, N., Ghosh, S. S., Kao, P. M., Fahy, E., Kwoh, D. Y., Guatelli, J. C., Spector, S. A., Richman, D. D., Gingeras, T. R.

“…Eighty-six peripheral blood mononuclear cell (PBMC) samples from 30 patients with AIDS were analyzed using a transcription-based amplification system (TAS) and…”
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Semisynthesis of an Antifungal Lipopeptide Echinocandin by Journet, Michel, Cai, Dongwei, DiMichele, Lisa M, Hughes, David L, Larsen, Robert D, Verhoeven, Thomas R, Reider, Paul J

“…Compound 1 is a macrocyclic lipopeptide belonging to the echinocandin family, which has been effective in treating systemic fungal infections. In this paper,…”
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Immune response to gastrin-17 and survival in gastrointestinal cancers by Oortgiesen, J. M., DiMichele, L. A., Weidman, J. R., Gunto, V. T., Soeder, T., Cato, A., Sutton, L.

“…Abstract only…”
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Commercialization of nucleic acid probe technology: current status by Godsey, J H, Vanden Brink, K M, DiMichele, L J, Beninsig, L A, Peterson, W R, Sherman, D G

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Design and synthesis of polyacrylamide-based oligonucleotide supports for use in nucleic acid diagnostics by Fahy, Eoin, David, Geneva R., DiMichele, Luke J., Ghosh, Soumitra S.

“…Polyacrylamlde supports, in a range of pore sizes, were Investigated as nucleic acid affinity matrices for the detection of target DNA or RNA sequences using a…”
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