Search Results - "DIMALINE, R"

The gastrins: their production and biological activities by Dockray, G J, Varro, A, Dimaline, R, Wang, T

“…Gastric epithelial organization and function are controlled and maintained by a variety of endocrine and paracrine mediators. Peptides encoded by the gastrin…”
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Feeding-dependent depression of melanin-concentrating hormone and melanin-concentrating hormone receptor-1 expression in vagal afferent neurones by Burdyga, G., Varro, A., Dimaline, R., Thompson, D.G., Dockray, G.J.

“…Food intake is regulated by signals from the gastrointestinal tract. Both stimulation and inhibition of food intake may be mediated by upper gastrointestinal…”
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Expression of the leptin receptor in rat and human nodose ganglion neurones by Burdyga, G, Spiller, D, Morris, R, Lal, S, Thompson, D.G, Saeed, S, Dimaline, R, Varro, A, Dockray, G.J

“…There is evidence for interactions between leptin and cholecystokinin in controlling food intake. Since cholecystokinin acts on vagal afferent neurones, we…”
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862 Differentially Expressed MicroRNAs in Gastric Cancer-associated Myofibroblasts by Wang, L, Steele, I, Dimaline, R, Hegyi, P, Puthen, J, Varro, A

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COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo by Ottewell, P D, Varro, A, Dockray, G J, Kirton, C M, Watson, A J M, Wang, T C, Dimaline, R, Pritchard, D M

“…Transgenic mice (hGAS) that overexpress human progastrin are more susceptible than wild-type mice (FVB/N) to the induction of colonic aberrant crypt foci (ACF)…”
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Expression and regulation of a vesicular monoamine transporter in rat stomach: a putative histamine transporter by Dimaline, R, Struthers, J

“…1. Vesicular monoamine transporters (VMATs) translocate monoamines from the cytoplasm into secretory vesicles of endocrine cells and neurones, but they have…”
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Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection by Bodger, K, Ahmed, S, Pazmany, L, Pritchard, D M, Micheal, A, Khan, A L, Dimaline, R, Dockray, G J, Varro, A

“…Matrix metalloproteinases (MMPs) have roles in inflammation and other processes relevant to the architectural disturbances seen in the gastric mucosa in…”
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Mutations of RegIα are associated with enterochromaffin-like cell tumor development in patients with hypergastrinemia by Higham, Andrew D., Bishop, Lisa A., Dimaline, Rod, Blackmore, Colin G., Dobbins, Andrew C., Varro, Andrea, Thompson, David G., Dockray, Graham J.

“…Background & Aims: The RegIα gene ( Reg) encodes a secretory protein proposed to regulate islet β-cell and gastric mucous cell growth. Reg is expressed in rat…”
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The ATPase activity of N-ethylmaleimide-sensitive fusion protein (NSF) is regulated by soluble NSF attachment proteins by Morgan, A, Dimaline, R, Burgoyne, R D

“…N-Ethylmaleimide-sensitive fusion protein (NSF) is an ATPase required in multiple stages of the secretory and endocytic pathways. NSF requires other proteins…”
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Gastric endocrine cells: gene expression, processing, and targeting of active products by Dockray, G J, Varro, A, Dimaline, R

“…Endocrine cells of the gastric epithelium secrete biologically active peptides and small messenger molecules such as histamine, serotonin, and…”
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Octreotide suppression test predicts beneficial outcome from antrectomy in a patient with gastric carcinoid tumor by Higham, Andrew D., Dimaline, Rod, Varro, Andrea, Attwood, Stephen, Armstrong, Gordon, Dockray, Graham J., Thompson, David G.

“…Multiple gastric carcinoids are a well-recognized complication of hypergastrinemia associated with chronic atrophic gastritis. However, the management of large…”
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Histidine decarboxylase gene expression in rat fundus is regulated by gastrin by Dimaline, R., Sandvik, A.K.

“…The conversion of histidine to histamine by histidine decarboxylase (HDC) is of central importance in the control of vertebrate acid secretion. We have used…”
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Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells by Hussain, I., Bate, G. W., Henry, J., Djali, P., Dimaline, R., Dockray, G. J., Varro, A.

“…Gastrointestinal endocrine cells produce biogenic amines which are transported into secretory vesicles by one of two proton-amine exchangers, vesicular…”
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Regulated expression of GATA-6 transcription factor in gastric endocrine cells by Dimaline, R, Campbell, BJ, Watson, F, Sandvik, AK, Struthers, J, Noble, PJ

“…BACKGROUND & AIMS: GATA transcription factors may regulate gene expression in developing tissues, including gut epithelium. In the stomach, their expression…”
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Regulation by gastric acid of the processing of progastrin-derived peptides in rat antral mucosa by Macro, J. A., Bate, G. W., Varro, A., Vaillant, C., Seidah, N. G., Dimaline, R., Dockray, G. J.

“…1. Inhibition of gastric acid secretion by proton pump inhibitors like omeprazole increases the synthesis and secretion of the pyloric antral hormone gastrin…”
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Identification and expression of prohormone-converting enzymes in the rat stomach by Macro, J A, Dimaline, R, Dockray, G J

“…The conversion of regulatory peptide precursors to their active forms usually involves limited proteolysis that may be mediated by subtilisin-like prohormone…”
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Food stimulation of histidine decarboxylase messenger RNA abundance in rat gastric fundus by Dimaline, R, Sandvik, A K, Evans, D, Forster, E R, Dockray, G J

“…1. Histidine decarboxylase in the enterochromaffin-like cells of the gastric corpus mucosa converts histidine to histamine which in turn stimulates gastric…”
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Modulation of the cleavage of the gastrin precursor by prohormone phosphorylation by Bishop, Lisa, Dimaline, Rod, Blackmore, Colin, Deavall, Damian, Dockray, Graham J., Varro, Andrea

“…Background & Aims: Amidated gastrins are acid secretagogues and growth factors. Their precursor, progastrin, is a growth factor but not a secretagogue…”
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Control of gastric corpus chromogranin A messenger RNA abundance in the rat by Dimaline, R, Evans, D, Forster, E R, Sandvik, A K, Dockray, G J

“…Enterochromaffin-like cells in the corpus mucosa of the stomach produce histamine in response to gastrin; chromogranin A (CGA) is often used as a morphological…”
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Novel form of L-aromatic amino acid decarboxylase mRNA in rat antral mucosa by Djali, P K, Dimaline, R, Dockray, G J

“…Gut endocrine cells possess the capacity to take up and decarboxylate biogenic amine precursors. Decarboxylation is mediated by aromatic L-amino acid…”
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