Search Results - "DILLON, Michael P"

Inter-Rater Reliability of Novice Linkers Using an Innovative Sequential Iterative Linking Method to Link Prosthetic Outcomes to The International Classification of Functioning, Disability and Health by Clarke, Leigh, Ridgewell, Emily, Li, Xia, Dillon, Michael P

“…When linking outcomes to the International Classification of Functioning, Disability and Health (ICF), inter-rater reliability is typically assessed at the…”
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Geographic Variation of the Incidence Rate of Lower Limb Amputation in Australia from 2007-12 by Dillon, Michael P, Fortington, Lauren V, Akram, Muhammad, Erbas, Bircan, Kohler, Friedbert

“…In Australia, little is known about how the incidence rate (IR) of lower limb amputation (LLA) varies across the country. While studies in other economically…”
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Regulation of the global orthotist/prosthetist workforce, and what we might learn from allied health professions with international-level regulatory support: a narrative review by Clarke, Leigh, Puli, Louise, Ridgewell, Emily, Dillon, Michael P, Anderson, Sarah

“…Abstract Background By 2050, the global demand for orthotic and prosthetic services is expected to double. Unfortunately, the orthotic/prosthetic workforce is…”
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Deliberations About the Functional Benefits and Complications of Partial Foot Amputation: Do We Pay Heed to the Purported Benefits at the Expense of Minimizing Complications? by Dillon, Michael P., PhD, Fatone, Stefania, PhD

“…Abstract While discussion about the benefits and complications of partial foot amputation (PFA) is not new, much of it has hinged on anecdotal evidence and led…”
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How patients interpret early signs of foot problems and reasons for delays in care: Findings from interviews with patients who have undergone toe amputations by Littman, Alyson J, Young, Jessica, Moldestad, Megan, Tseng, Chin-Lin, Czerniecki, Joseph R, Landry, Gregory J, Robbins, Jeffrey, Boyko, Edward J, Dillon, Michael P

“…To describe how patients respond to early signs of foot problems and the factors that result in delays in care. Semi-structured interviews were conducted with…”
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Inside the mind of a medicinal chemist: the role of human bias in compound prioritization during drug discovery by Kutchukian, Peter S, Vasilyeva, Nadya Y, Xu, Jordan, Lindvall, Mika K, Dillon, Michael P, Glick, Meir, Coley, John D, Brooijmans, Natasja

“…Medicinal chemists' "intuition" is critical for success in modern drug discovery. Early in the discovery process, chemists select a subset of compounds for…”
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The changing demographics of the orthotist/prosthetist workforce in Australia: 2007, 2012 and 2019 by Ridgewell, Emily, Clarke, Leigh, Anderson, Sarah, Dillon, Michael P

“…Previous Australian workforce analyses revealed a small orthotist/prosthetist workforce with a low number of practitioners per 100,000 Australians. In recent…”
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Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase by Lingel, Andreas, Sendzik, Martin, Huang, Ying, Shultz, Michael D, Cantwell, John, Dillon, Michael P, Fu, Xingnian, Fuller, John, Gabriel, Tobias, Gu, Justin, Jiang, Xiangqing, Li, Ling, Liang, Fang, McKenna, Maureen, Qi, Wei, Rao, Weijun, Sheng, Xijun, Shu, Wei, Sutton, James, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Hailong, Zhang, Maya, Zhao, Kehao, Lindvall, Mika, Bussiere, Dirksen E

“…PRC2 is a multisubunit methyltransferase involved in epigenetic regulation of early embryonic development and cell growth. The catalytic subunit EZH2…”
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Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF by Shao, Wenlin, Mishina, Yuji M, Feng, Yun, Caponigro, Giordano, Cooke, Vesselina G, Rivera, Stacy, Wang, Yingyun, Shen, Fang, Korn, Joshua M, Mathews Griner, Lesley A, Nishiguchi, Gisele, Rico, Alice, Tellew, John, Haling, Jacob R, Aversa, Robert, Polyakov, Valery, Zang, Richard, Hekmat-Nejad, Mohammad, Amiri, Payman, Singh, Mallika, Keen, Nicholas, Dillon, Michael P, Lees, Emma, Ramurthy, Savithri, Sellers, William R, Stuart, Darrin D

“…Resistance to the RAF inhibitor vemurafenib arises commonly in melanomas driven by the activated BRAF oncogene. Here, we report antitumor properties of RAF709,…”
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Exploring Factors Influencing Low Back Pain in People With Nondysvascular Lower Limb Amputation: A National Survey by Devan, Hemakumar, PhD, Hendrick, Paul, PhD, Hale, Leigh, PhD, Carman, Allan, PhD, Dillon, Michael P., PhD, Ribeiro, Daniel Cury, PhD

“…Abstract Background Chronic low back pain (LBP) is a common musculoskeletal impairment in people with lower limb amputation. Given the multifactorial nature of…”
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Design and Discovery of N‑(2-Methyl-5′-morpholino-6′-((tetrahydro‑2H‑pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers by Nishiguchi, Gisele A, Rico, Alice, Tanner, Huw, Aversa, Robert J, Taft, Benjamin R, Subramanian, Sharadha, Setti, Lina, Burger, Matthew T, Wan, Lifeng, Tamez, Victoriano, Smith, Aaron, Lou, Yan, Barsanti, Paul A, Appleton, Brent A, Mamo, Mulugeta, Tandeske, Laura, Dix, Ina, Tellew, John E, Huang, Shenlin, Mathews Griner, Lesley A, Cooke, Vesselina G, Van Abbema, Anne, Merritt, Hanne, Ma, Sylvia, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Wang, Yingyun, Haling, Jacob R, Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Jansen, Johanna M, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Lees, Emma, Shao, Wenlin, Stuart, Darrin D, Dillon, Michael P, Ramurthy, Savithri

“…RAS oncogenes have been implicated in >30% of human cancers, all representing high unmet medical need. The exquisite dependency on CRAF kinase in KRAS mutant…”
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A systematic review describing incidence rate and prevalence of dysvascular partial foot amputation; how both have changed over time and compare to transtibial amputation by Dillon, Michael P, Quigley, Matthew, Fatone, Stefania

“…Partial foot amputation (PFA) is a common consequence of advanced peripheral vascular disease. Given the different ways incidence rate and prevalence data have…”
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Interassessor agreement of portfolio-based competency assessment for orthotists/prosthetists in Australia : a mixed method study by Dillon, Michael P, Puli, Louise, Ridgewell, Emily, Anderson, Sarah P, Chiavaroli, Neville, Clarke, Leigh

“…Internationally qualified orthotists/prosthetists who want to practice in Australia must pass a portfolio-based competency assessment. Testing the agreement…”
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Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates by Karpov, Alexei S, Abrams, Tinya, Clark, Suzanna, Raikar, Ankita, D’Alessio, Joseph A, Dillon, Michael P, Gesner, Thomas G, Jones, Darryl, Lacaud, Marion, Mallet, William, Martyniuk, Piotr, Meredith, Erik, Mohseni, Morvarid, Nieto-Oberhuber, Cristina M, Palacios, Daniel, Perruccio, Francesca, Piizzi, Grazia, Zurini, Mauro, Bialucha, Carl Uli

“…Antibody–drug conjugates (ADCs) are a novel modality that allows targeted delivery of potent therapeutic agents to the desired site. Herein we report our…”
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Development of a Core Outcome Set for users and funders of lower-limb prosthetic interventions (PI-COS): a step to inform the benefits measured in prosthetic health economic evaluations by Clarke, Leigh, Ridgewell, Emily, Dillon, Michael P

“…Little is known about the outcomes that are most important to prosthesis users and funders. A Prosthetic Interventions Core Outcome Set (PI-COS) will help…”
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Content comparison of utility and effectiveness instruments to the Prosthetic Interventions Core Outcome Set: a step to inform the benefits measured in lower-limb prosthetic health economic evaluations by Clarke, Leigh, Ridgewell, Emily, Dillon, Michael P

“…Health Economic Evaluations (HEEs) calculate a cost-benefit ratio using utility and effectiveness instruments. It is unknown whether existing instruments…”
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Identifying and linking prosthetic outcomes to the ICF framework: a step to inform the benefits measured in prosthetic health economic evaluations by Clarke, Leigh, Ridgewell, Emily, Dillon, Michael P.

“…Prosthetic research seems focused on measuring gait-related outcomes that may not adequately measure real-world benefits of prosthetic interventions…”
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Purinoceptors as therapeutic targets for lower urinary tract dysfunction by Ford, Anthony P D W., Gever, Joel R., Nunn, Philip A., Zhong, Yu, Cefalu, Joseph S., Dillon, Michael P., Cockayne, Debra A.

“…Lower urinary tract symptoms (LUTS) are present in many common urological syndromes. However, their current suboptimal management by muscarinic and…”
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Letter to the Editor, RE: Berger et al. A Comparative Analysis of Functional and Patient-Reported Outcomes Following Lisfranc and Chopart Amputations in High-Risk Limb Salvage Patients. J Foot Ankle Surg. 2023. doi: 10.1053/j.jfas.2023.04.014 by Dillon, Michael P, Quigley, Matthew, Fatone, Stefania

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Physical activity participation amongst individuals with lower limb amputation by Langford, Jennifer, Dillon, Michael P., Granger, Catherine L., Barr, Chris

“…Purpose: To examine physical activity participation amongst individuals with lower limb amputation. Method: Adults with lower limb amputation were…”
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