Search Results - "DIGBY, J"

Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis by De Crescenzo, Franco, D'Alò, Gian Loreto, Ostinelli, Edoardo G, Ciabattini, Marco, Di Franco, Valeria, Watanabe, Norio, Kurtulmus, Ayse, Tomlinson, Anneka, Mitrova, Zuzana, Foti, Francesca, Del Giovane, Cinzia, Quested, Digby J, Cowen, Phil J, Barbui, Corrado, Amato, Laura, Efthimiou, Orestis, Cipriani, Andrea

“…Behavioural, cognitive, and pharmacological interventions can all be effective for insomnia. However, because of inadequate resources, medications are more…”
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Actigraphic features of bipolar disorder: a systematic review and meta-analysis by De Crescenzo, Franco, M.D., M.Sc, Economou, Alexis, Sharpley, Ann L, Gormez, Aynur, Quested, Digby J

“…Summary Sleep disruptions represent a core feature of bipolar disorders and have been widely studied through the use of actigraphy, which is an objective…”
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The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo by Panaro, Brandon L., Tough, Iain R., Engelstoft, Maja S., Matthews, Robert T., Digby, Gregory J., Møller, Cathrine L., Svendsen, Berit, Gribble, Fiona, Reimann, Frank, Holst, Jens J., Holst, Birgitte, Schwartz, Thue W., Cox, Helen M., Cone, Roger D.

“…The melanocortin-4 receptor (MC4R) is expressed in the brainstem and vagal afferent nerves and regulates a number of aspects of gastrointestinal function. Here…”
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GPR109A Is a G-protein―Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon by THANGARAJU, Muthusamy, CRESCI, Gail A, PRASAD, Puttur D, GANAPATHY, Vadivel, KEBIN LIU, ANANTH, Sudha, GNANAPRAKASAM, Jaya P, BROWNING, Darren D, MELLINGER, John D, SMITH, Sylvia B, DIGBY, Gregory J, LAMBERT, Nevin A

“…Short-chain fatty acids, generated in colon by bacterial fermentation of dietary fiber, protect against colorectal cancer and inflammatory bowel disease. Among…”
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The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers by Hollins, Bettye, Kuravi, Sudhakiranmayi, Digby, Gregory J., Lambert, Nevin A.

“…Signals mediated by heterotrimeric G proteins often develop over the course of tens of milliseconds, and could require either conformational rearrangement or…”
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Excess AGN activity in the z= 2.30 Protocluster in HS 1700+64 by Digby-North, J. A., Nandra, K., Laird, E. S., Steidel, C. C., Georgakakis, A., Bogosavljević, M., Erb, D. K., Shapley, A. E., Reddy, N. A., Aird, J.

“…We present the results of spectroscopic, narrow-band and X-ray observations of a z= 2.30 protocluster in the field of the QSO HS 1700+643. Using a sample of…”
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Melatonin In Acute Mania Investigation (MIAMI‐UK). A randomized controlled trial of add‐on melatonin in bipolar disorder by Quested, Digby J., Gibson, Jessica C., Sharpley, Ann L., Cordey, Julia H., Economou, Alexis, De Crescenzo, Franco, Voysey, Merryn, Lawson, Jennifer, Rendell, Jennifer M., Al‐Taiar, Hasanen, Lennox, Alison, Ahmad, Farooq, Geddes, John R.

“…Objectives Current options for treating emergent episodes of hypomania and mania in bipolar disorder are limited. Our objective was to compare the…”
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Reproductive skew in female common marmosets: what can proximate mechanisms tell us about ultimate causes? by Saltzman, Wendy, Digby, Leslie J, Abbott, David H

“…Common marmosets are cooperatively breeding monkeys that exhibit high reproductive skew: most subordinate females fail to reproduce, while others attempt to…”
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Secretion of adiponectin by human placenta : differential modulation of adiponectin and its receptors by cytokines by CHEN, J, TAN, B, KARTERIS, E, ZERVOU, S, DIGBY, J, HILLHOUSE, E. W, VATISH, M, RANDEVA, H. S

“…Pregnancy, a state of insulin resistance, is associated with elevated levels of cytokines and profound alterations in metabolism. Serum adiponectin, an…”
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A Population-Based Study of the Clinical Expression of the Hemochromatosis Gene by Olynyk, John K, Cullen, Digby J, Aquilia, Sina, Rossi, Enrico, Summerville, Lesa, Powell, Lawrie W

“…Hereditary hemochromatosis is a common inherited disorder of iron metabolism. 1 – 4 Recently, a new major-histocompatibility-complex class I–like candidate…”
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Some G Protein Heterotrimers Physically Dissociate in Living Cells by Digby, Gregory J., Lober, Robert M., Sethi, Pooja R., Lambert, Nevin A.

“…Heterotrimeric G proteins mediate physiological processes ranging from phototransduction to cell migration. In the accepted model of G protein signaling, Gαβγ…”
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Low faecal haemoglobin concentration potentially rules out significant colorectal disease by McDonald, P. J., Digby, J., Innes, C., Strachan, J. A., Carey, F. A., Steele, R. J. C., Fraser, C. G.

“…Aim The study aimed to determine whether faecal haemoglobin (Hb) concentration can assist in deciding who with lower abdominal symptoms will benefit from…”
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Orexin receptor expression in human adipose tissue: effects of orexin-A and orexin-B by Digby, J E, Chen, J, Tang, J Y, Lehnert, H, Matthews, R N, Randeva, H S

“…Orexin-A and orexin-B, via their receptors orexin-1 receptor (OX1R) and orexin-2 receptor (OX2R) have been shown to play a role in the regulation of feeding,…”
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A population-based study of the biochemical and clinical expression of the H63D hemochromatosis mutation by Gochee, Peter A., Powell, Lawrie W., Cullen, Digby J., Du Sart, Desiree, Rossi, Enrico, Olynyk, John K.

“…Two major mutations are defined within the hemochromatosis gene, HFE. Although the effects of the C282Y mutation have been well characterized, the effects of…”
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Infrared Excess sources: Compton thick QSOs, low-luminosity Seyferts or starbursts? by Georgakakis, A., Rowan-Robinson, M., Nandra, K., Digby-North, J., Pérez-González, P. G., Barro, G.

“…We explore the nature of Infrared Excess sources (IRX), which are proposed as candidates for luminous [LX(2–10 keV) > 1043 erg s−1] Compton thick (NH > 2 ×…”
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Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders by Digby, Gregory J, Shirey, Jana K, Conn, P Jeffrey

“…Muscarinic acetylcholine receptors (mAChRs) represent exciting therapeutic targets for the treatment of multiple CNS disorders. The high degree of conservation…”
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Differential dissociation of G protein heterotrimers by Digby, Gregory J., Sethi, Pooja R., Lambert, Nevin A.

“…Signalling by heterotrimeric G proteins is often isoform-specific, meaning certain effectors are regulated exclusively by one family of heterotrimers. For…”
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Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome by TAN, B. K, CHEN, J, DIGBY, J. E, KEAY, S. D, KENNEDY, C. R, RANDEVA, H. S

“…Polycystic ovary syndrome (PCOS) is a multifaceted metabolic disease linked with insulin resistance (IR) and obesity. Adiponectin, which is lower in IR states,…”
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Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution by Montague, C. T., Prins, J. B., Sanders, L., Digby, J. E., O'Rahilly, S.

“…Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. C T Montague , J B Prins , L…”
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Congenital leptin deficiency is associated with severe early-onset obesity in humans by O'Rahilly, Stephen, Montague, Carl T, Farooqi, I. Sadaf, Whitehead, Jonathan P, Soos, Maria A, Rau, Harald, Wareham, Nicholas J, Sewter, Ciaran P, Digby, Janet E, Mohammed, Shehla N, Hurst, Jane A, Cheetham#, Christopher H, Earley#, Alison R, Barnett, Anthony H, Prins, Johannes B

“…The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene encoding leptin, an adipocyte-specific secreted protein which has…”
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