Search Results - "DIEROV, J"
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BCR ABL induces chromosomal instability after genotoxic stress and alters the cell death threshold
Published in Leukemia (01-02-2009)“…Earlier reports have suggested that the BCR/ABL oncogene, associated with chronic myeloid leukemia, induces a mutator phenotype; however, it is unclear whether…”
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Increased G1 cyclin/cdk activity in cells overexpressing the candidate oncogene, MCT-1
Published in Journal of cellular biochemistry (15-09-1999)“…We have recently identified a novel candidate oncogene, MCT‐1, in the HUT 78 T‐cell line. When overexpressed in NIH3T3 fibroblasts, the MCT‐1 gene shortens the…”
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BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint
Published in Cancer cell (01-03-2004)“…Chronic myelogeneous leukemia (CML) is a two-stage disease associated with expression of the BCR/ABL tyrosine kinase protein. However, whether BCR/ABL…”
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TEL/platelet-derived growth factor receptor β activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle
Published in Blood (01-03-2002)“…TEL/platelet-derived growth factor receptor β (PDGFβR) is the protein product of the t(5;12) translocation in chronic myelomonocytic leukemia. TEL/PDGFβR…”
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A novel candidate oncogene, MCT-1, is involved in cell cycle progression
Published in Cancer research (Chicago, Ill.) (01-10-1998)“…Using the arbitrarily primed-PCR (AP-PCR) assay to detect genetic abnormalities that occur in a panel of lymphoid cell lines, we identified an amplified…”
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Retinoic Acid Modulates a Bimodal Effect on Cell Cycle Progression in Human Adult T-Cell Leukemia Cells
Published in Clinical cancer research (01-09-1999)“…Retinoids, the analogues of vitamin A, have a broad range of effects on different cell types. One biologically active form of vitamin A is all- trans -retinoic…”
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TEL-JAK2 constitutively activates the extracellular signal–regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways
Published in Blood (15-08-2002)“…The ets transcription factor, TEL, undergoes chromosomal rearrangements with the tyrosine kinase JAK2. TEL-JAK2 is constitutively active, confers cell line…”
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Lipolytic activity of California‐laurel (Umbellularia californica) seeds
Published in Journal of the American Oil Chemists' Society (01-10-2001)“…The lipid content of dormant mature seeds of the California‐laurel (Umbellularia califonnica) was 74% (mass basis) and decreased upon germination, reaching 43%…”
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