Search Results - "DIDSBURY, J. R"
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Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization
Published in The Journal of biological chemistry (15-11-1993)“…To define the regulation of chemoattractant receptors, epitope-tagged human formyl peptide and C5a receptor cDNAs (ET-FR and ET-C5aR) were stably expressed in…”
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Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation
Published in The Journal of immunology (1950) (01-10-1994)“…The formylpeptide (fMLP) and C5a chemoattractants were previously shown to cross-desensitize each other's ability to mobilize Ca2+ in leukocytes but not to…”
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Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum
Published in The Journal of biological chemistry (25-05-1992)“…We purified a novel ADP-ribosyltransferase produced by a Clostridium limosum strain isolated from a lung abscess and compared the exoenzyme with Clostridium…”
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Receptor Class Desensitization of Leukocyte Chemoattractant Receptors
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-1991)“…To better define their regulation, formylpeptide and C5a chemoattractant receptor cDNAs were transiently expressed with high efficiency (≈ 35-54%) in human…”
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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
Published in Nature (London) (20-02-1997)“…Tumour-necrosis factor-alpha (TNF-alpha) is a cytokine that contributes to a variety of inflammatory disease states. The protein exists as a membrane-bound…”
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Identification of the ral and rac1 Gene Products, Low Molecular Mass GTP-binding Proteins from Human Platelets
Published in The Journal of biological chemistry (05-10-1989)“…Identification of the GTP-binding proteins from human platelet particulate fractions was attained by their purification via successive column chromatography…”
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Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia
Published in The Journal of biological chemistry (05-06-1987)“…The ferritin family is a widespread group of proteins that maintain iron in a soluble form and also protect against the toxic effects of excess iron. The…”
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Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5'-untranslated regions
Published in The Journal of biological chemistry (15-01-1986)“…Ferritin maintains iron in a bioavailable, nontoxic form for vertebrates and invertebrates, higher plants, fungi, and bacteria; the protein is formed from two…”
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Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells
Published in Molecular and Cellular Biology (01-07-1983)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: possible role in membrane localization
Published in Biochemical and biophysical research communications (14-09-1990)“…Ras proteins can be modified at their COOH-terminal cysteine in the motif Cys-Ali-Ali-Xaa by a farnesyl isoprenoid. This modification is essential for membrane…”
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Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs
Published in FEBS letters (10-02-1992)“…Human kidney 293 TSA cells were transfected by a calcium phosphate method with human formylpeptide and C5a receptor cDNAs with high efficiency. Formylpeptide…”
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Molecular cloning of a new human G protein Evidence for two Giα‐like protein families
Published in FEBS letters (13-07-1987)“…The amino acid sequence of a novel G protein α subunit (Gxα) has been deduced from the nucleotide sequence of a human cDNA clone isolated from a differentiated…”
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Human Gi protein α‐subunit: deduction of amino acid structure from a cloned cDNA
Published in FEBS letters (26-01-1987)“…The amino acid sequence of the α‐subunit of Gi, the human adenylate cyclase inhibiting GTP‐binding protein, has been deduced from the nucleotide sequence of a…”
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NF-κ B Activation Provides the Potential Link between Inflammation and Hyperplasia in the Arthritic Joint
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-1998)“…The transcription factor NF-κ B is a pivotal regulator of inflammatory responses. While the activation of NF-κ B in the arthritic joint has been associated…”
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Rac1, a low‐molecular‐mass GTP‐binding‐protein with high intrinsic GTPase activity and distinct biochemical properties
Published in European journal of biochemistry (01-06-1992)“…Rac1, a member of the family of low‐molecular‐mass GTP‐binding proteins, functions in phagocytic leukocytes as a component necessary for activation of the…”
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NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-1998)“…The transcription factor NF-kappaB is a pivotal regulator of inflammatory responses. While the activation of NF-kappaB in the arthritic joint has been…”
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Differential regulation of cAMP by endogenous versus transfected formylpeptide chemoattractant receptors: implications for Gi-coupled receptor signaling
Published in Biochemical and biophysical research communications (31-03-1992)“…Endogenous neutrophil formylpeptide receptors do not inhibit adenylylcyclase activation. The ability of a cloned and transfected human formylpeptide receptor…”
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Human G sub(i) protein alpha -subunit: Deduction of amino acid structure from a cloned cDNA
Published in FEBS letters (01-01-1987)“…The amino acid sequence of the alpha -subunit of G sub(i), the human adenylate cyclase inhibiting GTP-binding protein, has been deduced from the nucleotide…”
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