Search Results - "DICKLER, H. B"

Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation by Hathcock, Karen S., Laszlo, Gloria, Dickler, Howard B., Bradshaw, Jeff, Linsley, Peter, Hodes, Richard J.

“…Stimulation of T cell proliferation generally requires two signals: The first signal is provided by the T cell receptor binding to antigen, and the second…”
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Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells by Laszlo, G, Hathcock, KS, Dickler, HB, Hodes, RJ

“…A mAb, GL7, is described that reacts with a 35-kDa protein on subsets of activated mouse B cells as well as activated CD4+ and CD8+ peripheral T cells. In…”
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Cooperativity between B lymphocyte membrane molecules: independent ligand occupancy and cross-linking of antigen receptors and Fc gamma receptors down-regulates B lymphocyte function by Uher, F, Dickler, HB

“…IgG antibody-antigen complexes bound to B lymphocyte Fc gamma receptor (Fc gamma R) but not surface immunoglobulin inhibit the antibody-forming cell response…”
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IL-4 induces loss of B lymphocyte Fc gamma R II ligand binding capacity by Laszlo, G, Dickler, HB

“…Murine B lymphocytes cultured for 24 h with rIL-4 lost (mean reduction of 88%, range 81 to 96%) the capacity to bind Ag-IgG antibody complexes to B lymphocytes…”
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Vaccines: New approaches and concepts by Dickler, Howard B., Collier, Elaine

“…Vaccine research has become an exciting area with notable progress on many fronts. Examples of advances include new approaches to antigen delivery, immunologic…”
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Current perspectives on the use of intravenous immunoglobulin by Dickler, H B, Gelfand, E W

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Evidence for Individual Human Peripheral Blood Lymphocytes bearing both B and T Cell Markers by DICKLER, H. B, ADKINSON, N. F, TERRY, W. D

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Detection of low numbers of lymphocyte surface membrane molecules using concentration immunofluorescence analysis (CIA) by Laszlo, G, Dickler, H B

“…Using viable lymphocytes in a concentration immunofluorescence assay (CIA), conditions were ascertained which allow detection of low numbers of surface…”
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Anti-idiotype stimulation of antigen-specific antigen-independent antibody responses in vitro. II. Triggering of B lymphocytes by idiotype plus anti-idiotype in the absence of T lymphocytes by Shenk, RR, Weissberger, HZ, Dickler, HB

“…Antibodies specific for the idiotypes of B10 anti-(T,G)-A--L antibodies (anti-id) induced B lymphocytes to secrete anti-(T,G)-A--L antibodies in vitro in the…”
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Definitive mapping of the immune response gene(s) for (T,G)-A--L to the I-A subregion by Markman, M, Dickler, HB

“…Mice of strains B10, B10.A, B10.A(4R), B10.A(5R), and the new recombinant inbred strain B10.MBR (H-2 genotype Kb, Ik, Sk. Dq) were immunized with (T,G)-A--L…”
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Inhibition of lymphocyte mitogenesis by immobilized antigen-antibody complexes by Ryan, J L, Arbeit, R D, Dickler, H B, Henkart, P A

“…Mouse spleen cells, cultured on surfaces coated with antigen-antibody complexes, are inhibited from responding to the B-cell mitogens, lipopolysaccharide,…”
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Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia by Dickler, H B, Siegal, F P, Bentwich, Z H, Kunkel, H G

“…Eleven selected patients with chronic lymphocytic leukaemia were evaluated for lymphocyte binding of aggregated IgG and surface Ig staining in order to…”
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Studies of Ia antigens on murine peritoneal macrophages by Schwartz, R H, Dickler, H B, Sachs, D H, Schwartz, B D

“…Murine peritoneal cells, both induced and noninduced, were examined for Ia antigens by a variety of techniques. Complement-mediated cytotoxicity and indirect…”
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Ly-39: a new lymphocyte alloantigen defined with a monoclonal antibody by PARK, E, PRINCIPATO, M. A, LAMERS, M. C, DICKLER, H. B

“…A new lymphocyte alloantigen (Ly-39.1) which is preferentially expressed on activated B lymphocytes and whose expression is controlled by a gene located…”
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Interactions between lymphocyte membrane molecules. II. Characterization of an interaction between B lymphocyte surface IgD and Fc IgG receptors that differs from the surface IgM-Fc IgG receptor interaction by Dickler, HB, Kubicek, MT, Finkelman, FD

“…The B lymphocyte surface membrane receptors IgD (sigD) and Fc IgG receptors (Fc gamma R) were evaluated for interactions by means of immunofluorescence…”
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Human Lymphocyte Alloantigen(s) Similar to Murine Ir Region-Associated (Ia) Antigens by Arbeit, Robert D, Sachs, David H, Amos, D. Bernard, Dickler, Howard B

“…Summary An anti-HL-A human alloantiserum contained antibodies specific for B lymphocyte alloantigen(s). These antigens were distinct from HL-A antigens and,…”
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Aortic ball variance by Dickler, H B

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Studies on the Nature of the Relationship Between Ia Antigens and Fc Receptors on Murine B Lymphocytes by Dickler, Howard B, Kubicek, Mary T, Arbeit, Robert D, Sharrow, Susan O

“…Abstract Possible mechanisms for the specific inhibition by anti-Ia antibody of the binding of Ig complexes to B lymphocyte Fc receptors were evaluated…”
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Gene therapy in the treatment of disease by Dickler, Howard B., Collier, Elaine

“…Gene therapy or transfer is increasingly used as a therapeutic modality in diseases that span the medical spectrum. The American Academy of Allergy and…”
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Lymphocytes in patients with variable immunodeficiency and panhypogammaglobulinemia. Evaluation of B and T cell surface markers and a proposed classification by Dickler, H B, Adkinson, Jr, N F, Fisher, R I, Terry, W D

“…Peripheral blood lymphocytes from 15 patients with variable immunodeficiency and severe panhypogammaglobulinemia were evaluated for B and T cell surface…”
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