Search Results - "DICKINSON, PATSY S."

Neuropeptidergic Signaling in the American Lobster Homarus americanus: New Insights from High-Throughput Nucleotide Sequencing by Christie, Andrew E, Chi, Megan, Lameyer, Tess J, Pascual, Micah G, Shea, Devlin N, Stanhope, Meredith E, Schulz, David J, Dickinson, Patsy S

“…Peptides are the largest and most diverse class of molecules used for neurochemical communication, playing key roles in the control of essentially all aspects…”
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The role of feedback and modulation in determining temperature resiliency in the lobster cardiac nervous system by Powell, Daniel J, Owens, Elizabeth, Bergsund, Marie M, Cooper, Maren, Newstein, Peter, Berner, Emily, Janmohamed, Rania, Dickinson, Patsy S

“…Changes in ambient temperature affect all biological processes. However, these effects are process specific and often vary non-linearly. It is thus a…”
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Does Differential Receptor Distribution Underlie Variable Responses to a Neuropeptide in the Lobster Cardiac System? by Muscato, Audrey J, Walsh, Patrick, Pong, Sovannarath, Pupo, Alixander, Gross, Roni J, Christie, Andrew E, Hull, J Joe, Dickinson, Patsy S

“…Central pattern generators produce rhythmic behaviors independently of sensory input; however, their outputs can be modulated by neuropeptides, thereby…”
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Diversity of neuropeptidergic modulation in decapod crustacean cardiac and feeding systems by Dickinson, Patsy S., Powell, Daniel J.

“…All nervous systems are multiply modulated by polypeptides. However, a bulk of transmitter and modulation research has historically focused on small molecule…”
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Crustacean neuropeptides by Christie, Andrew E., Stemmler, Elizabeth A., Dickinson, Patsy S.

“…Crustaceans have long been used for peptide research. For example, the process of neurosecretion was first formally demonstrated in the crustacean…”
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Neuromodulation of central pattern generators in invertebrates and vertebrates by Dickinson, Patsy S

“…Central pattern generators are subject to extensive modulation that generates flexibility in the rhythmic outputs of these neural networks. The effects of…”
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Identification and cardiotropic actions of sulfakinin peptides in the American lobster Homarus americanus by Dickinson, Patsy S, Stevens, Jake S, Rus, Szymon, Brennan, Henry R, Goiney, Christopher C, Smith, Christine M, Li, Lingjun, Towle, David W, Christie, Andrew E

“…In arthropods, a group of peptides possessing a -Y((SO3H))GHM/LRFamide carboxy-terminal motif have been collectively termed the sulfakinins. Sulfakinin…”
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Neuropeptide modulation of pattern-generating systems in crustaceans: comparative studies and approaches by Dickinson, Patsy S, Qu, Xuan, Stanhope, Meredith E

“…Highlights • Mass spectrometry is used to identify and localize neuropeptides across crustaceans. • Transcriptomics allows peptide and receptor prediction from…”
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Midgut epithelial endocrine cells are a rich source of the neuropeptides APSGFLGMRamide (Cancer borealis tachykinin-related peptide Ia) and GYRKPPFNGSIFamide (Gly1-SIFamide) in the crabs Cancer borealis, Cancer magister and Cancer productus by Christie, Andrew E, Kutz-Naber, Kimberly K, Stemmler, Elizabeth A, Klein, Alexandra, Messinger, Daniel I, Goiney, Christopher C, Conterato, Anna J, Bruns, Emily A, Hsu, Yun-Wei A, Li, Lingjun, Dickinson, Patsy S

“…Over a quarter of a century ago, Mykles described the presence of putative endocrine cells in the midgut epithelium of the crab Cancer magister (Mykles, 1979)…”
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Isoforms of the neuropeptide myosuppressin differentially modulate the cardiac neuromuscular system of the American lobster, Homarus americanus by Oleisky, Emily R, Stanhope, Meredith E, Hull, J Joe, Dickinson, Patsy S

“…Post-translational modifications (PTMs) diversify peptide structure and allow for greater flexibility within signaling networks. The cardiac neuromuscular…”
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Mass Spectrometry Quantification, Localization, and Discovery of Feeding-Related Neuropeptides in Cancer borealis by DeLaney, Kellen, Hu, Mengzhou, Hellenbrand, Tessa, Dickinson, Patsy S, Nusbaum, Michael P, Li, Lingjun

“…The crab Cancer borealis nervous system is an important model for understanding neural circuit dynamics and modulation, but the identity of neuromodulatory…”
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SIFamide peptides in clawed lobsters and freshwater crayfish (Crustacea, Decapoda, Astacidea): A combined molecular, mass spectrometric and electrophysiological investigation by Dickinson, Patsy S, Stemmler, Elizabeth A, Cashman, Christopher R, Brennan, Henry R, Dennison, Bobbi, Huber, Kristen E, Peguero, Braulio, Rabacal, Whitney, Goiney, Christopher C, Smith, Christine M, Towle, David W, Christie, Andrew E

“…Abstract Recently, we identified the peptide VYRKPPFNGSIFamide (Val1 -SIFamide) in the stomatogastric nervous system (STNS) of the American lobster Homarus…”
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Identification of A-type allatostatins possessing -YXFGI/Vamide carboxy-termini from the nervous system of the copepod crustacean Calanus finmarchicus by Christie, Andrew E, Sousa, Gregory L, Rus, Szymon, Smith, Christine M, Towle, David W, Hartline, Daniel K, Dickinson, Patsy S

“…The copepod crustacean Calanus finmarchicus plays a critical role in the ecology of the Gulf of Maine and other regions of the North Atlantic. To increase our…”
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Prediction of a neuropeptidome for the eyestalk ganglia of the lobster Homarus americanus using a tissue-specific de novo assembled transcriptome by Christie, Andrew E, Roncalli, Vittoria, Cieslak, Matthew C, Pascual, Micah G, Yu, Andy, Lameyer, Tess J, Stanhope, Meredith E, Dickinson, Patsy S

“…Highlights • An eyestalk transcriptome consisting of 147,542 unique contigs was generated. • Two hundred sixty-two distinct mature neuropeptides were…”
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Related neuropeptides use different balances of unitary mechanisms to modulate the cardiac neuromuscular system in the American lobster, Homarus americanus by Dickinson, Patsy S, Calkins, Andrew, Stevens, Jake S

“…To produce flexible outputs, neural networks controlling rhythmic motor behaviors can be modulated at multiple levels, including the pattern generator itself,…”
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Structural variation between neuropeptide isoforms affects function in the lobster cardiac system by Muscato, Audrey J., Powell, Daniel J., Bulhan, Warsameh, Mackenzie, Evalyn S., Pupo, Alixander, Rolph, Madeline, Christie, Andrew E., Dickinson, Patsy S.

“…•AST-C isoforms elicit both similar and different responses in the lobster heart.•C-terminal amidation does not account for the different responses to AST-C…”
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Differential neuropeptide modulation of premotor and motor neurons in the lobster cardiac ganglion by Oleisky, Emily R, Stanhope, Meredith E, Hull, J Joe, Christie, Andrew E, Dickinson, Patsy S

“…The American lobster, , cardiac neuromuscular system is controlled by the cardiac ganglion (CG), a central pattern generator consisting of four premotor and…”
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Distinct or shared actions of peptide family isoforms: I. Peptide-specific actions of pyrokinins in the lobster cardiac neuromuscular system by Dickinson, Patsy S, Sreekrishnan, Anirudh, Kwiatkowski, Molly A, Christie, Andrew E

“…Although the crustacean heart is modulated by a large number of peptides and amines, few of these molecules have been localized to the cardiac ganglion itself;…”
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SIFamide peptides modulate cardiac activity differently in two species of Cancer crab by Dickinson, Patsy S., Samuel, Heidi M., Stemmler, Elizabeth A., Christie, Andrew E.

“…•Cardiotropic effects of two SIFamide isoforms were assessed on two Cancer species.•Both Gly1- and Val1-SIFamide were found to be cardioactive in both crab…”
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Inter-animal variability in the effects of C-type allatostatin on the cardiac neuromuscular system in the lobster Homarus americanus by Wiwatpanit, Teerawat, Powers, Brian, Dickinson, Patsy S

“…Although the global effects of many modulators on pattern generators are relatively consistent among preparations, modulators can induce different alterations…”
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