Search Results - "DICKER, A. J"

The lower airway microbiome in paediatric health and chronic disease by Campbell, S, Gerasimidis, K, Milling, S, Dicker, AJ, Hansen, R, Langley, RJ

“…The reader will gain an improved understanding of:•Key terminology used in microbiome research for respiratory paediatrician.•The methods used to investigate…”
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Cytochrome P450, CYP26AI, is expressed at low levels in human epidermal keratinocytes and is not retinoic acid-inducible by POPA, C, DICKER, A. J, DAHLER, A. L, SAUNDERS, N. A

“…Retinoids, and their synthetic analogues, are well‐established regulators of the squamous differentiation programme both in vivo and in vitro. Despite this,…”
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E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes by DICKER, A. J, POPA, C, DAHLER, A. L, SEREWKO, M. M, HILDITCH-MAGUIRE, P. A, FRAZER, I. H, SAUNDERS, N. A

“…Squamous differentiation of keratinocytes is associated with decreases in E2F-1 mRNA expression and E2F activity, and these processes are disrupted in squamous…”
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E2F as a Regulator of Keratinocyte Proliferation: Implications for Skin Tumor Development by Jones, Susan J., Dicker, Anthony J., Dahler, Alison L., Saunders, Nicholas A.

“…E2F and DP family members are established regulators of the cell cycle. In this study, we examined their activity/expression during keratinocyte growth arrest…”
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E2F1 messenger RNA is destabilized in response to a growth inhibitor in normal human keratinocytes but not in a squamous carcinoma cell line by SAUNDERS, N. A, DICKER, A. J, JONES, S. J, DAHLER, A. L

“…Keratinocyte growth arrest is characterized by a reduction in the activity and expression of E2F1. Here, we examine the role posttranscriptional processing…”
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B16 CYSTIC FIBROSIS (CF) AND NON-CF BRONCHIECTASIS: Identifying Modifiable Risk Factors For Rapid Lung Function Decline In Bronchiectasis by Fardon, T, Finch, S M, Crichton, M, Dicker, A J, Marshall, S, Chalmers, J D

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D94 ADVANCES IN CYSTIC FIBROSIS AND NON-CYSTIC FIBROSIS BRONCHIECTASIS: Neutrophil Extracellular Traps Are Associated With Disease Severity In Bronchiectasis by Pumphrey, E, Keir, H, Fong, C, Finch, S, Fardon, T C, Dicker, A J, Chalmers, J D

“…Clinical assessments included lung function, exacerbation frequency, Quality of life (St. Georges Respiratory Questionnaire- SGRQ), hospital admissions and…”
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A31 MECHANISMS IN CYSTIC FIBROSIS AND OTHER BRONCHIECTATIC DISEASES: Validating New Methods Of Quantifying Neutrophil Extracellular Traps In Sputum And Bronchoalveolar Lavage From Patients With COPD And Bronchiectasis by Pumphrey, E, Keir, H, Fong, C, Sibila, O, Suarez-Cuartin, G, Finch, S, Fardon, T C, Dicker, A J, Chalmers, J D

“…Results: Sputum samples from 171 COPD patients and 257 bronchiectasis patients contained high concentrations of cell free DNA, variable levels of NE activity…”
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A62 CLINICAL ASPECTS OF CAP, HCAP, HAP, AND VAP: Neutrophil Extracellular Traps Are Associated With Disease Severity In Chronic Obstructive Pulmonary Disease by Fong, C, Dicker, A J, Crichton, M, Suarez-Cuartin, G, Sibila, O, Schembri, S, Marshall, S, Palmer, C N A, Chalmers, J D

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A21 CHRONIC AIRWAY INFLAMMATION: MICROBIAL INFLUENCE: Mannose Binding Lectin Deficient Haplotypes Are Associated With Fewer Exacerbations And A More Diverse Microbiome In Chronic Obstructive Pulmonary Disease by Dicker, A J, Crichton, M, Cassidy, A, Brady, G, Hapca, A, Einarsson, G G, Elborn, J, Schembri, S, Marshall, S, Palmer, C N A, Chalmers, J D

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Functional Characterization of Cultured Cells Derived from an Intraepidermal Carcinoma of the Skin (IEC-1) by Dicker, Anthony J., Serewko, Magdalena M., Dahler, Alison L., Khanna, Kum Kum, Kaur, Pritinder, Li, Amy, Strutton, Geoff M., Saunders, Nicholas A.

“…We have successfully isolated a cell line (IEC-1) from an intraepidermal carcinoma of the skin of a patient and compared its behavior, in vitro, to normal…”
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B16 CYSTIC FIBROSIS (CF) AND NON-CF BRONCHIECTASIS: Altered Lung Microbiota Profiles Are Associated With Disease Severity, Exacerbation Frequency And Neutrophilic Inflammation In Bronchiectasis by Dicker, A J, Fong, C, Crichton, M, Cassidy, A, Suarez-Cuartin, G, Sibila, O, Einarsson, G G, Ibrahim, W, Elborn, J, Palmer, C N A, Fardon, T, Marshall, S, Chalmers, J D

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Amelanotic lentigo maligna and amelanotic lentigo maligna melanoma: a report of three cases mimicking intraepidermal squamous carcinoma by Allan, S.J.R, Dicker, A.J, Tidman, M.J, McLaren, K.M, Hunter, J.A.A

“…The clinical diagnosis of amelanotic melanoma may pose diagnostic difficulties. We report three cases of amelanotic lentigo maligna, two of which developed an…”
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Alterations in gene expression and activity during squamous cell carcinoma development by SEREWKO, Magdalena M, POPA, Claudia, DAHLER, Alison L, SMITH, Louise, STRUTTON, Geoff M, COMAN, William, DICKER, Anthony J, SAUNDERS, Nicholas A

“…This study focuses on characterizing the genetic and biological alterations associated with squamous cell carcinoma development. Normal human epidermal…”
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Disbiosis microbiana en las bronquiectasias y la fibrosis quística by Dicker, Alison J, Chalmers, James D

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Keratinocyte growth arrest is associated with activation of a transcriptional repressor element in the human cdk1 promoter by Dahler, Alison L., Jones, Susan J., Dicker, Anthony J., Saunders, Nicholas A.

“…In this study we examined the regulation of cdk1 expression in normal human epidermal keratinocytes (HEKs) and neoplastic keratinocytes. Keratinocytes were…”
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Cytochrome P540, CYP26AI, is expressed at low levels in human epidermal keratinocytes and is not retinoic acid-inducible by Popa, C, Dicker, A J, Dahler, A L, Saunders, N A

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Amelanotic lentigo maligna and amelanotic lentigo maligna melanoma: a report of three cases mimicking intraepidermal squamous carcinoma by Allan, S. J.R., Dicker, A.J., Tidman, M.J., McLaren, K.M., Hunter, J.A.A.

“…The clinical diagnosis of amelanotic melanoma may pose diagnostic difficulties. We report three cases of amelanotic lentigo maligna, two of which developed an…”
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Isolation (From a Basal Cell Carcinoma) of a Functionally Distinct Fibroblast-Like Cell Type that Overexpresses Ptch by Dicker, Anthony J., Serewko, Magdalena M., Russell, Terry, Dahler, Alison L., Saunders, Nicholas A., Rothnagel, Joseph A., Strutton, Geoff M.

“…In this study we report on the isolation and characterization of a nonepithelial, nontumorigenic cell type (BCC1) derived from a basal cell carcinoma from a…”
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