Search Results - "DIAZ, Marvin R"
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Moderate Adolescent Ethanol Vapor Exposure and Acute Stress in Adulthood: Sex-Dependent Effects on Social Behavior and Ethanol Intake in Sprague-Dawley Rats
Published in Brain sciences (01-11-2020)“…Adolescent alcohol use can lead to numerous consequences, including altered stress reactivity and higher risk for later anxiety and alcohol use disorders. Many…”
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Chronic Ethanol and Withdrawal Differentially Modulate Pre- and Postsynaptic Function at Glutamatergic Synapses in Rat Basolateral Amygdala
Published in Journal of neurophysiology (01-12-2007)“…1 Department of Physiology and Pharmacology, 2 Alcohol Training Program, and 3 Neuroscience Training Program, Wake Forest University School of Medicine,…”
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Stress alters social behavior and sensitivity to pharmacological activation of kappa opioid receptors in an age-specific manner in Sprague Dawley rats
Published in Neurobiology of stress (01-11-2018)“…The dynorphin/kappa opioid receptor (DYN/KOR) system has been identified as a primary target of stress due to behavioral effects, such as dysphoria, aversion,…”
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Moderate Maternal Alcohol Exposure on Gestational Day 12 Impacts Anxiety-Like Behavior in Offspring
Published in Frontiers in behavioral neuroscience (29-09-2017)“…Among the numerous consequences of prenatal alcohol exposure (PAE) is an increase in anxiety-like behavior that can prove debilitating to daily functioning. A…”
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Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses
Published in The Journal of pharmacology and experimental therapeutics (01-04-2011)“…Withdrawal-related anxiety is cited as a major contributor to relapse in recovering alcoholics. Changes in lateral/basolateral amygdala (BLA) neurotransmission…”
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Na+/K+-ATPase inhibition partially mimics the ethanol-induced increase of the Golgi cell-dependent component of the tonic GABAergic current in rat cerebellar granule cells
Published in PloS one (2013)“…Cerebellar granule cells (CGNs) are one of many neurons that express phasic and tonic GABAergic conductances. Although it is well established that Golgi cells…”
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Moderate prenatal alcohol exposure modifies sex-specific CRFR1 activity in the central amygdala and anxiety-like behavior in adolescent offspring
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2022)“…Anxiety disorders are highly prevalent among individuals with a history of prenatal alcohol exposure (PAE), and adolescent rodents demonstrate anxiety-like…”
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Factors of sex and age dictate the regulation of GABAergic activity by corticotropin-releasing factor receptor 1 in the medial sub-nucleus of the central amygdala
Published in Neuropharmacology (15-05-2021)“…Adolescents are phenotypically characterized with hyper-sensitivity to stress and inappropriate response to stress-inducing events. Despite behavioral…”
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Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen
Published in Psychopharmacologia (01-09-2007)“…Existing data strongly suggest that alcohol affects dopamine (DA) neurotransmission in the brain. However, many questions remain about the effects of alcohol…”
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Bestrophin1 Channels are Insensitive to Ethanol and Do not Mediate Tonic GABAergic Currents in Cerebellar Granule Cells
Published in Frontiers in neuroscience (01-01-2012)“…The granule cell layer of the cerebellum functions in spatio-temporal encoding of information. Granule cells (GCs) are tonically inhibited by spillover of GABA…”
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Prenatal methadone exposure leads to long‐term memory impairments and disruptions of dentate granule cell function in a sex‐dependent manner
Published in Addiction biology (01-09-2022)“…Prenatal opioid exposures lead to extensive cognitive and emotion‐regulation problems in children, persisting at least through school‐age. Methadone, an opioid…”
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Moderate adolescent chronic intermittent ethanol exposure sex-dependently disrupts synaptic transmission and kappa opioid receptor function in the basolateral amygdala of adult rats
Published in Neuropharmacology (01-05-2021)“…Adolescent alcohol exposure is associated with many consequences in adulthood, including altered affective and reward-related behaviors. However, the long-term…”
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Increased ethanol intake is associated with social anxiety in offspring exposed to ethanol on gestational day 12
Published in Behavioural brain research (01-09-2020)“…•Prenatal alcohol exposure (PAE) alters social anxiety-like behavior.•Social anxiety and ethanol intake are highly associated.•PAE increases ethanol intake in…”
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Does moderate drinking harm the fetal brain? Insights from animal models
Published in Trends in neurosciences (Regular ed.) (01-05-2012)“…Although public health campaigns advise pregnant women to abstain from ethanol, drinking during pregnancy is pervasive. Here, we highlight recent studies that…”
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Acute prenatal exposure to ethanol on gestational day 12 elicits opposing deficits in social behaviors and anxiety-like behaviors in Sprague Dawley rats
Published in Behavioural brain research (01-09-2016)“…•Ethanol exposure in mid-gestation alters social behavior in Sprague Dawley rats.•Ethanol-exposed male offsprings show deficits from early adolescence through…”
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Age and sex regulate kappa opioid receptor-mediated anxiety-like behavior in rats
Published in Behavioural brain research (03-02-2020)“…•Kappa opioid receptors (KOR) are involved in anxiety.•Females and adolescent males may be less sensitive to KOR effects than adult males.•KOR activation…”
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Third trimester-equivalent ethanol exposure increases anxiety-like behavior and glutamatergic transmission in the basolateral amygdala
Published in Pharmacology, biochemistry and behavior (01-10-2015)“…Ethanol consumption during pregnancy produces a wide range of morphological and behavioral alterations known as fetal alcohol spectrum disorder (FASD). Among…”
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Prenatal methadone exposure leads to disruptions in adult-born dentate granule cell survival and female persistent fear responding
Published in Addiction neuroscience (01-12-2023)“…Methadone is used for the treatment of opioid use disorder, including in pregnant patients. Research has established several consequences of prenatal opioid…”
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Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus
Published in The Journal of neuroscience (16-01-2013)“…Although it is well documented that heavy consumption of alcohol during pregnancy impairs brain development, it remains controversial whether moderate…”
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