Search Results - "DIAKOS, Nikolaos A"

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure by Cluntun, Ahmad A., Badolia, Rachit, Lettlova, Sandra, Parnell, K. Mark, Shankar, Thirupura S., Diakos, Nikolaos A., Olson, Kristofor A., Taleb, Iosif, Tatum, Sean M., Berg, Jordan A., Cunningham, Corey N., Van Ry, Tyler, Bott, Alex J., Krokidi, Aspasia Thodou, Fogarty, Sarah, Skedros, Sophia, Swiatek, Wojciech I., Yu, Xuejing, Luo, Bai, Merx, Shannon, Navankasattusas, Sutip, Cox, James E., Ducker, Gregory S., Holland, William L., McKellar, Stephen H., Rutter, Jared, Drakos, Stavros G.

“…The metabolic rewiring of cardiomyocytes is a widely accepted hallmark of heart failure (HF). These metabolic changes include a decrease in mitochondrial…”
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Cardiac, skeletal, and smooth muscle mitochondrial respiration: are all mitochondria created equal? by Park, Song-Young, Gifford, Jayson R, Andtbacka, Robert H I, Trinity, Joel D, Hyngstrom, John R, Garten, Ryan S, Diakos, Nikolaos A, Ives, Stephen J, Dela, Flemming, Larsen, Steen, Drakos, Stavros, Richardson, Russell S

“…Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial…”
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Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical Unloading by Wever-Pinzon, James, MD, Selzman, Craig H., MD, Stoddard, Greg, MPH, MBA, Wever-Pinzon, Omar, MD, Catino, Anna, MD, Kfoury, Abdallah G., MD, Diakos, Nikolaos A., MD, Reid, Bruce B., MD, McKellar, Stephen, MD, Bonios, Michael, MD, PhD, Koliopoulou, Antigone, MD, Budge, Deborah, MD, Kelkhoff, Aaron, MD, Stehlik, Josef, MD, Fang, James C., MD, Drakos, Stavros G., MD, PhD

“…Abstract Background Small-scale studies focused mainly on nonischemic cardiomyopathy (NICM) have shown that a subset of left ventricular assist device (LVAD)…”
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Myocardial Atrophy and Chronic Mechanical Unloading of the Failing Human Heart by Diakos, Nikolaos A., MD, Selzman, Craig H., MD, Sachse, Frank B., PhD, Stehlik, Josef, MD, Kfoury, Abdallah G., MD, Wever-Pinzon, Omar, MD, Catino, Anna, MD, Alharethi, Rami, MD, Reid, Bruce B., MD, Miller, Dylan V., MD, Salama, Mohamed, MD, Zaitsev, Alexey V., PhD, Shibayama, Junko, PhD, Li, Hui, MD, Fang, James C., MD, Li, Dean Y., MD, PhD, Drakos, Stavros G., MD, PhD

“…Abstract Background In animal models of heterotopic transplantation, mechanical unloading of the normal, nonhypertrophic heart results in atrophy. Primarily on…”
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Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice by Chan, Aubrey C, Drakos, Stavros G, Ruiz, Oscar E, Smith, Alexandra C H, Gibson, Christopher C, Ling, Jing, Passi, Samuel F, Stratman, Amber N, Sacharidou, Anastasia, Revelo, M Patricia, Grossmann, Allie H, Diakos, Nikolaos A, Davis, George E, Metzstein, Mark M, Whitehead, Kevin J, Li, Dean Y

“…Cerebral cavernous malformations (CCMs) are a common type of vascular malformation in the brain that are a major cause of hemorrhagic stroke. This condition…”
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Management of Cardiogenic Shock: Present and Future by Diakos, Nikolaos A

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Afterload‐induced left ventricular diastolic dysfunction during myocardial ischaemia and reperfusion by Diakos, Nikolaos A., Pozios, Iraklis, Katsaros, Lampros, Vakrou, Styliani, Sventzouri, Stefania, Michelinakis, Nikolaos, Tseliou, Eleni, Bonios, Michael, Malliaras, Konstantinos, Papalois, Apostolos, Anastasiou‐Nana, Maria, Terrovitis, John V.

“…New Findings What is the central question of this study? While the load dependence of the diastolic function is established for the normal heart, little is…”
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Magnitude and Time Course of Changes Induced by Continuous-Flow Left Ventricular Assist Device Unloading in Chronic Heart Failure by Drakos, Stavros G., MD, PhD, Wever-Pinzon, Omar, MD, Selzman, Craig H., MD, Gilbert, Edward M., MD, Alharethi, Rami, MD, Reid, Bruce B., MD, Saidi, Abdulfattah, MD, Diakos, Nikolaos A., MD, Stoker, Sandi, RN, Davis, Erin S., RN, BSN, Movsesian, Matthew, MD, Li, Dean Y., MD, PhD, Stehlik, Josef, MD, Kfoury, Abdallah G., MD

“…Objectives This study sought to prospectively investigate the longitudinal effects of continuous-flow left ventricular assist device (LVAD) unloading on…”
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Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure by Pepin, Mark E., Ha, Chae-Myeong, Crossman, David K., Litovsky, Silvio H., Varambally, Sooryanarayana, Barchue, Joseph P., Pamboukian, Salpy V., Diakos, Nikolaos A., Drakos, Stavros G., Pogwizd, Steven M., Wende, Adam R.

“…Ischemic cardiomyopathy (ICM) is the clinical endpoint of coronary heart disease and a leading cause of heart failure. Despite growing demands to develop…”
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Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading by Seidel, Thomas, Navankasattusas, Sutip, Ahmad, Azmi, Diakos, Nikolaos A, Xu, Weining David, Tristani-Firouzi, Martin, Bonios, Michael J, Taleb, Iosif, Li, Dean Y, Selzman, Craig H, Drakos, Stavros G, Sachse, Frank B

“…Cardiac recovery in response to mechanical unloading by left ventricular assist devices (LVADs) has been demonstrated in subgroups of patients with chronic…”
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Magnitude and Time Course of Changes Induced by Continuous-Flow Left Ventricular Assist Device Unloading in Chronic Heart Failure: Insights Into Cardiac Recovery by DRAKOS, Stavros G, WEVER-PINZON, Omar, MOVSESIAN, Matthew, LI, Dean Y, STEHLIK, Josef, KFOURY, Abdallah G, SELZMAN, Craig H, GILBERT, Edward M, ALHARETHI, Rami, REID, Bruce B, SAIDI, Abdulfattah, DIAKOS, Nikolaos A, STOKER, Sandi, DAVIS, Erin S

“…This study sought to prospectively investigate the longitudinal effects of continuous-flow left ventricular assist device (LVAD) unloading on myocardial…”
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Conditional Survival After HeartMate 3 Implantation: An Analysis of the MOMENTUM 3 Trial by BALACHANDRAN, ISABEL C., SEGAR, MATTHEW W., DIAKOS, NIKOLAOS A., ROGERS, JOSEPH G.

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Interventional Heart Failure: Current State of the Field by Alvarez Villela, Miguel, Liu, Spencer, Yin, Michael, Esposito, Michele L., Aghili, Nima, Mustehsan, Muhammad H., Larson, Ian, Diakos, Nikolaos A., Kapur, Navin K.

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Systemic Inflammatory Burden Correlates with Severity and Predicts Outcomes in Patients with Cardiogenic Shock Supported by a Percutaneous Mechanical Assist Device by Diakos, Nikolaos A., Thayer, Katherine, Swain, Lija, Goud, Maithri, Jain, Pankaj, Kapur, Navin K.

“…In-hospital mortality associated with cardiogenic shock (CS) remains high despite introduction of mechanical circulatory support. In this study, we aimed to…”
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Correction to: Systemic Inflammatory Burden Correlates with Severity and Predicts Outcomes in Patients with Cardiogenic Shock Supported by a Percutaneous Mechanical Assist Device by Diakos, Nikolaos A., Thayer, Katherine, Swain, Lija, Goud, Maithri, Jain, Pankaj, Kapur, Navin K.

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Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock by Diakos, Nikolaos A., Swain, Lija, Bhave, Shreyas, Qiao, Xiaoying, Libermann, Towia, Haywood, Jillian, Goel, Siya, Annamalai, Shiva, Esposito, Michele, Chweich, Haval, Faugno, Anthony, Kapur, Navin K.

“…In-hospital mortality associated with cardiogenic shock (CS) remains high despite the use of percutaneous assist devices. We sought to determine whether…”
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Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery by Diakos, Nikolaos A, Selzman, Craig H, Sachse, Frank B, Stehlik, Josef, Kfoury, Abdallah G, Wever-Pinzon, Omar, Catino, Anna, Alharethi, Rami, Reid, Bruce B, Miller, Dylan V, Salama, Mohamed, Zaitsev, Alexey V, Shibayama, Junko, Li, Hui, Fang, James C, Li, Dean Y, Drakos, Stavros G

“…In animal models of heterotopic transplantation, mechanical unloading of the normal, nonhypertrophic heart results in atrophy. Primarily on the basis of these…”
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A Rare Case of Disseminated Tuberculosis and Hematological Malignancy in a Heart Transplant Recipient by Slomovich, Sharon, Oh, Kyung Taek, Diakos, Nikolaos A., Restaino, Susan W., Clerkin, Kevin J., Latif, Farhana, Miyauchi, Jeremy T., Lee, Anna, Sayer, Gabriel T., Uriel, Nir

“…A 77-year-old man who underwent a heart transplant 7 years ago presented with multiple bloody bowel movements. Endoscopic and histologic evaluation revealed…”
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Clinical and histopathological effects of heart failure drug therapy in advanced heart failure patients on chronic mechanical circulatory support by Catino, Anna B., Ferrin, Peter, Wever‐Pinzon, James, Horne, Benjamin D., Wever‐Pinzon, Omar, Kfoury, Abdallah G., McCreath, Lauren, Diakos, Nikolaos A., McKellar, Stephen, Koliopoulou, Antigone, Bonios, Michael J., Al‐Sarie, Mohammad, Taleb, Iosif, Dranow, Elizabeth, Fang, James C., Drakos, Stavros G.

“…Aims Adjuvant heart failure (HF) drug therapy in patients undergoing chronic mechanical circulatory support (MCS) is often used in conjunction with a…”
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Circulating and Myocardial Cytokines Predict Cardiac Structural and Functional Improvement in Patients With Heart Failure Undergoing Mechanical Circulatory Support by Diakos, Nikolaos A, Taleb, Iosif, Kyriakopoulos, Christos P, Shah, Kevin S, Javan, Hadi, Richins, Tyler J, Yin, Michael Y, Yen, Chi-Gang, Dranow, Elizabeth, Bonios, Michael J, Alharethi, Rami, Koliopoulou, Antigone G, Taleb, Mariam, Fang, James C, Selzman, Craig H, Stellos, Konstantinos, Drakos, Stavros G

“…Background Recent prospective multicenter data from patients with advanced heart failure demonstrated that left ventricular assist device (LVAD) support…”
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