Search Results - "DI TUCCI, Anna"
-
1
Valproic Acid at Therapeutic Plasma Levels May Increase 5-Azacytidine Efficacy in Higher Risk Myelodysplastic Syndromes
Published in Clinical cancer research (01-08-2009)“…Purpose: Epigenetic changes play a role and cooperate with genetic alterations in the pathogenesis of myelodysplastic syndromes (MDS). We conducted a phase II…”
Get full text
Journal Article -
2
Myocardial iron overload assessment by T2 magnetic resonance imaging in adult transfusion dependent patients with acquired anemias
Published in Haematologica (Roma) (01-09-2008)“…1 Ematologia e Centro Trapianti, Centro Oncologico di Riferimento regionale "Armando Businco", Cagliari 2 Radiologia Ospedale "Brotzu", Cagliari 3 Ematologia…”
Get full text
Journal Article -
3
Iron overload, cardiac iron loading and function in myelodysplastic syndrome
Published in Leukemia research (01-06-2009)Get full text
Journal Article -
4
Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial
Published in Annals of internal medicine (21-04-2020)“…Iron chelation therapy (ICT) in patients with lower-risk myelodysplastic syndromes (MDS) has not been evaluated in randomized studies. To evaluate event-free…”
Get full text
Journal Article -
5
Patient‐reported outcomes enhance the survival prediction of traditional disease risk classifications: An international study in patients with myelodysplastic syndromes
Published in Cancer (15-03-2018)“…BACKGROUND Current prognostic systems for myelodysplastic syndromes (MDS) are based on clinical, pathologic, and laboratory indicators. The objective of the…”
Get full text
Journal Article -
6
Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial)
Published in European journal of haematology (01-06-2014)“…Background In the absence of randomized, controlled trial data to support iron chelation therapy in transfusion‐dependent patients with myelodysplastic…”
Get full text
Journal Article -
7
Overall survival of myelodysplastic syndrome patients after azacitidine discontinuation and applicability of the North American MDS Consortium scoring system in clinical practice
Published in Cancer (15-06-2021)“…Background Azacitidine (AZA) is the standard treatment for myelodysplastic syndromes (MDS); however, many patients prematurely stop therapy and have a dismal…”
Get full text
Journal Article -
8
-
9
Update of the GIMEMA MDS0306 study: Deferasirox for lower risk transfusion‐dependent patients with myelodysplastic syndromes
Published in European journal of haematology (01-05-2019)Get full text
Journal Article -
10
Autologous Stem Cell Transplantation in Acute Myeloid Leukemia; A Single Centre “Real Life” Study
Published in Blood (06-12-2014)“…Background. Autologous stem cell transplant is a consolidation treatment for standard risk acute myeloid leukemia (AML). Traditional preparative regimens, most…”
Get full text
Journal Article -
11
Once Daily Intravenous Busulphan Plus Fludarabine As New Reduced Toxicity Myeloablative Conditioning for Acute Myeloid Leukemia and MDS Allogeneic Transplantation
Published in Blood (06-12-2014)“…▪ Background. Allogeneic hemopoietic stem cell transplantation is the treatment of choice for high and intermediate risk acute myeloid leukemia (AML) and for…”
Get full text
Journal Article -
12
Impact of Transfusion Dependency on Health-Related Quality of Life Outcomes in Newly Diagnosed Patients with Myelodysplastic Syndromes (MDS). Analysis on 669 Patients By Disease Risk
Published in Blood (08-12-2017)“…Background: There is some evidence indicating that transfusion dependency negatively impact health-related quality of life HRQOL of patients with…”
Get full text
Journal Article -
13
Inclusion of Patient's Self-Reported Fatigue into a Standard Laboratory Risk Classification Enhances Survival Prediction in Patients with Advanced Myelodysplastic Syndromes
Published in Blood (02-12-2016)“…BACKGROUND: Patients with higher risk myelodysplastic syndromes (MDS) according to the International Prognostic Scoring System (IPSS) have poor life expectancy…”
Get full text
Journal Article -
14
Clinical Outcomes of 420 MDS Patients Treated with 5-Azacytidine: Evaluation of Overall Survival, Duration of Treatment and Rate of Discontinuation in a Real Life Study from the Italian MDS Registry of Fondazione Italiana Sindromi Mielodisplastiche (FISM)
Published in Blood (02-12-2016)“…▪ Introduction Azacytidine(AZA) is the current standard of care for patients with high-risk myelodysplastic syndrome (MDS) in Europe. AZA has shown a survival…”
Get full text
Journal Article -
15
Higher Versus Standard Doses of Recombinant Erythropoietin for the Treatment of Anemia in Patients with Myelodysplastic Syndromes: Results of a Retrospective Survey from the Italian Registry of Myelodisplastic Syndromes (FISM)
Published in Blood (02-12-2016)“…▪ Introduction: Erythropoietic stimulating agents (ESAs) have not yet received FDA nor EMA approval to treat anemia of myelodysplastic syndromes (MDS), but…”
Get full text
Journal Article -
16
A genome wide association study by Immunochip reveals potential modifiers in myelodysplastic syndromes
Published in Experimental hematology (01-11-2016)“…Abstract As different findings suggest that an immune dysregulation play a role in the pathogenesis of MDS, we analysed a large cohort of patients from a…”
Get full text
Journal Article -
17
Correction of anemia in a transfusion‐dependent patient with primary myelofibrosis receiving iron chelation therapy with deferasirox (Exjade®, ICL670)
Published in European journal of haematology (01-06-2007)“…Transfusional iron overload in patients with chronic anemias can result in multiple organ failure. Experience in the management of iron overload in patients…”
Get full text
Journal Article -
18
Health-Related Quality Of Life In Transfusion-Dependent Patients With Myelodysplastic Syndromes Treated With Deferasirox. A Multicenter Prospective Study
Published in Blood (15-11-2013)“…Anemia is a common symptom in patients with Myelodysplastic Syndromes (MDS) and although erythropoietic agents are often active, it is frequently treated with…”
Get full text
Journal Article -
19
Health-related quality of life in transfusion-dependent patients with myelodysplastic syndromes: a prospective study to assess the impact of iron chelation therapy
Published in BMJ supportive & palliative care (01-03-2016)“…The primary objective of this study was to evaluate the health-related quality of life (HRQOL) in lower-risk, transfusion-dependent patients with…”
Get more information
Journal Article -
20
The evolving clinical scenario of myelodysplastic syndrome: The need for a complete and up to date upfront diagnostic assessment
Published in European journal of internal medicine (01-12-2010)“…Abstract Until the beginning of the current millennium, few concrete therapeutic possibilities were available for myelodysplastic syndrome (MDS) patients. This…”
Get full text
Journal Article