Search Results - "DI MAURO, Ernesto"

A Universal Geochemical Scenario for Formamide Condensation and Prebiotic Chemistry by Saladino, Raffaele, Di Mauro, Ernesto, García‐Ruiz, Juan Manuel

“…The condensation of formamide has been shown to be a robust chemical pathway affording molecules necessary for the origin of life. It has been experimentally…”
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The role of borosilicate glass in Miller–Urey experiment by Criado-Reyes, Joaquín, Bizzarri, Bruno M., García-Ruiz, Juan Manuel, Saladino, Raffaele, Di Mauro, Ernesto

“…We have designed a set of experiments to test the role of borosilicate reactor on the yielding of the Miller–Urey type of experiment. Two experiments were…”
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Emergence of the First Catalytic Oligonucleotides in a Formamide-Based Origin Scenario by Šponer, Judit E., Šponer, Jiří, Nováková, Olga, Brabec, Viktor, Šedo, Ondrej, Zdráhal, Zbyněk, Costanzo, Giovanna, Pino, Samanta, Saladino, Raffaele, Di Mauro, Ernesto

“…50 years after the historical Miller–Urey experiment, the formamide‐based scenario is perhaps the most powerful concurrent hypothesis for the origin of life on…”
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Silica Metal Oxide Vesicles Catalyze Comprehensive Prebiotic Chemistry by Mattia Bizzarri, Bruno, Botta, Lorenzo, Pérez‐Valverde, Maritza Iveth, Saladino, Raffaele, Di Mauro, Ernesto, García‐Ruiz, Juan Manuel

“…It has recently been demonstrated that mineral self‐assembled structures catalyzing prebiotic chemical reactions may form in natural waters derived from…”
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Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context by Saladino, Raffaele, Bizzarri, Bruno M., Botta, Lorenzo, Šponer, Jiří, Šponer, Judit E., Georgelin, Thomas, Jaber, Maguy, Rigaud, Baptiste, Kapralov, Mikhail, Timoshenko, Gennady N., Rozanov, Alexei, Krasavin, Eugene, Timperio, Anna Maria, Mauro, Ernesto Di

“…The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to…”
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Role of histone acetylation in the control of gene expression by Verdone, Loredana, Caserta, Micaela, Di Mauro, Ernesto

“…Histone proteins play structural and functional roles in all nuclear processes. They undergo different types of covalent modifications, defined in their…”
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Non-Enzymatic Oligomerization of 3', 5' Cyclic AMP by Costanzo, Giovanna, Pino, Samanta, Timperio, Anna Maria, Šponer, Judit E, Šponer, Jiří, Nováková, Olga, Šedo, Ondrej, Zdráhal, Zbyněk, Di Mauro, Ernesto

“…Recent studies illustrate that short oligonucleotide sequences can be easily produced from nucleotide precursors in a template-free non-enzymatic way under…”
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Male Sexual Dysfunction and Infertility in Spinal Cord Injury Patients: State-of-the-Art and Future Perspectives by Di Bello, Francesco, Creta, Massimiliano, Napolitano, Luigi, Califano, Gianluigi, Passaro, Francesco, Morra, Simone, Giovanni, Angelo di, Fusco, Giovanni Maria, Cirillo, Luigi, Abate, Marco, Morgera, Vincenzo, Cacace, Gianluigi, De Luca, Luigi, Spena, Gianluca, Collà Ruvolo, Claudia, Calace, Francesco Paolo, Manfredi, Celeste, La Rocca, Roberto, Celentano, Giuseppe, Turco, Carmine, Capece, Marco, D’Alterio, Carlo, Giordano, Alessandro, Mauro, Ernesto di, Trama, Francesco, Amicuzi, Ugo, Arcaniolo, Davide, Fusco, Ferdinando, Longo, Nicola

“…Spinal cord injury (SCI) is a relevant medical and social problem. According to the World Health Organization, the commonly estimated worldwide annual…”
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Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA by Saladino, Raffaele, Šponer, Judit E, Šponer, Jiří, Costanzo, Giovanna, Pino, Samanta, Di Mauro, Ernesto

“…Molecular Darwinian evolution is an intrinsic property of reacting pools of molecules resulting in the adaptation of the system to changing conditions. It has…”
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From formamide to RNA, the path is tenuous but continuous by Pino, Samanta, Sponer, Judit E, Costanzo, Giovanna, Saladino, Raffaele, Mauro, Ernesto Di

“…Reactions of formamide (NH2COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large…”
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Enantioselective reactions catalyzed by synthetic enzymes. A model for chemical evolution by Colonna, Stefano, Perdicchia, Dario, Mauro, Ernesto Di

“…Polyleucines of various lengths act as enantioselective catalysts in the aldol condensation between cyclohexanone and various aromatic aldehydes. Polyleucine…”
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Genetics first or metabolism first? The formamide clue by Saladino, Raffaele, Botta, Giorgia, Pino, Samanta, Costanzo, Giovanna, Di Mauro, Ernesto

“…Life is made of the intimate interaction of metabolism and genetics, both built around the chemistry of the most common elements of the Universe (hydrogen,…”
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Meteorites as Catalysts for Prebiotic Chemistry by Saladino, Raffaele, Botta, Giorgia, Delfino, Michela, Di Mauro, Ernesto

“…From outer space: Twelve meteorite specimens, representative of their major classes, catalyse the synthesis of nucleobases, carboxylic acids, aminoacids and…”
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Determinism of formamide-based biogenic prebiotic reactions by Saladino, Raffaele, Bizzarri, Bruno Mattia, Mauro, Ernesto Di

“…•Formamide provides the very composition of the pool of compounds: all the precursors of RNA are present in the same pot, along with numerous amino acids and…”
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Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation by Saladino, Raffaele, Carota, Eleonora, Botta, Giorgia, Kapralov, Mikhail, Timoshenko, Gennady N., Rozanov, Alexei Y., Krasavin, Eugene, Di Mauro, Ernesto

“…Liquid formamide has been irradiated by high-energy proton beams in the presence of powdered meteorites, and the products of the catalyzed resulting syntheses…”
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A Global Scale Scenario for Prebiotic Chemistry: Silica-Based Self-Assembled Mineral Structures and Formamide by Saladino, Raffaele, Botta, Giorgia, Bizzarri, Bruno Mattia, Di Mauro, Ernesto, Garcia Ruiz, Juan Manuel

“…The pathway from simple abiotically made organic compounds to the molecular bricks of life, as we know it, is unknown. The most efficient geological abiotic…”
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Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites by Saladino, Raffaele, Crestini, Claudia, Ciambecchini, Umberto, Ciciriello, Fabiana, Costanzo, Giovanna, Di Mauro, Ernesto

“…We describe the role of formamide, a product of the hydrolysis of hydrogen cyanide, as precursor of several components of nucleic acids under prebiotic…”
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Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP by Samanta Pino, Giovanna Costanzo, Alessandra Giorgi, Jiří Šponer, Judit E. Šponer, Ernesto Di Mauro

“…3′,5′-Cyclic GMP spontaneously nonenzymatically polymerizes in a base-catalyzed reaction affording G oligonucleotides. When reacted with fully or partially…”
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The key role of meteorites in the formation of relevant prebiotic molecules in a formamide/water environment by Rotelli, Luca, Trigo-Rodríguez, Josep M., Moyano-Cambero, Carles E., Carota, Eleonora, Botta, Lorenzo, Di Mauro, Ernesto, Saladino, Raffaele

“…We show that carbonaceous chondrite meteorites actively and selectively catalyze the formation of relevant prebiotic molecules from formamide in aqueous media…”
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On the Observable Transition to Living Matter by Pino, Samanta, Trifonov, Edward N., Di Mauro, Ernesto

“…In recent developments in chemistry and genetic engineering, the humble researcher dealing with the origin of life finds her（him）self in a grey area of…”
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