Search Results - "DI CESARE, L"

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    Development of solid lipid nanoparticles as carriers for improving oral bioavailability of glibenclamide by Gonçalves, L.M.D., Maestrelli, F., Di Cesare Mannelli, L., Ghelardini, C., Almeida, A.J., Mura, P.

    “…[Display omitted] A solid lipid nanoparticle (SLN) formulation was developed with the aim of improving the oral bioavailability and the therapeutic…”
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    Journal Article
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    Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy by Resta, F., Micheli, L., Laurino, A., Spinelli, V., Mello, T., Sartiani, L., Di Cesare Mannelli, L., Cerbai, E., Ghelardini, C., Romanelli, M.N., Mannaioni, G., Masi, A.

    Published in Neuropharmacology (15-03-2018)
    “…Chemotherapy-Induced Peripheral Neuropathy (CIPN) is the most frequent adverse effect of pharmacological cancer treatments. The occurrence of neuropathy…”
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    Journal Article
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    Yellow grub diseases on two seasonal killifish (Cyprinodontiformes, Rivulidae): a histopathological study by Di Cesare, L., Montes, M. M., Vargas, M. S., Barbeito, C. G., Plaul, S. E.

    Published in Parasitology research (1987) (2024)
    “…Yellow grub disease is a parasite infection, caused by Clinostomum spp. Metacercariae and affecting axial muscles and internal organs of freshwater fish…”
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    Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism by Di Cesare Mannelli, Lorenzo, D'Agostino, G., Pacini, A., Russo, R., Zanardelli, Matteo, Ghelardini, Carla, Calignano, A.

    Published in Mediators of Inflammation (01-01-2013)
    “…Neuropathic syndromes which are evoked by lesions to the peripheral or central nervous system are extremely difficult to treat, and available drugs rarely…”
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  5. 5

    Oxaliplatin-induced oxidative stress in nervous system-derived cellular models: Could it correlate with in vivo neuropathy? by Di Cesare Mannelli, L., Zanardelli, M., Failli, P., Ghelardini, C.

    Published in Free radical biology & medicine (01-08-2013)
    “…Oxaliplatin is a platinum-organic drug with antineoplastic properties used for colorectal cancer. With respect to the other platinum derivates oxaliplatin…”
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    Persulfidation of mitoKv7.4 channels contributes to the cardioprotective effects of the H2S-donor Erucin against ischemia/reperfusion injury by Testai, L., Montanaro, R., Flori, L., Pagnotta, E., Vellecco, V., Gorica, E., Ugolini, L., Righetti, L., Brancaleone, V., Bucci, M., Piragine, E., Martelli, A., Di Cesare Mannelli, L., Ghelardini, C., Calderone, V.

    Published in Biochemical pharmacology (01-09-2023)
    “…[Display omitted] Hydrogen sulfide (H2S) is a gasotransmitter deeply involved in cardiovascular homeostasis and implicated in the myocardial protection against…”
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    Environmental training is beneficial to clinical symptoms and cortical presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis by Bonfiglio, T., Olivero, G., Vergassola, M., Di Cesare Mannelli, L., Pacini, A., Iannuzzi, F., Summa, M., Bertorelli, R., Feligioni, M., Ghelardini, C., Pittaluga, A.

    Published in Neuropharmacology (01-02-2019)
    “…The effect of “prophylactic” environmental stimulation on clinical symptoms and presynaptic defects in mice suffering from the experimental autoimmune…”
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    Journal Article
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    Neuropathy-induced apoptosis: Protective effect of physostigmine by Di Cesare Mannelli, L., Bartolini, A., Ghelardini, C.

    Published in Journal of neuroscience research (01-06-2009)
    “…Traumatic, infectious, metabolic, and chemical noxa to the nervous system are the etiology of a crippling disease generally termed neuropathy. Motor disorders,…”
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    Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial by Ratziu, V., de Guevara, L., Safadi, R., Poordad, F., Fuster, F., Flores-Figueroa, J., Arrese, M., Fracanzani, Anna L., Ben Bashat, D., Lackner, K., Gorfine, T., Kadosh, S., Oren, R., Halperin, M., Hayardeny, L., Loomba, R., Friedman, S., Sanyal, Arun J.

    Published in Nature Medicine (01-10-2021)
    “…Nonalcoholic steatohepatitis (NASH), a chronic liver disease without an approved therapy, is associated with lipotoxicity and insulin resistance and is a major…”
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    Journal Article Magazine Article
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    Acetyl- l -carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy by Vivoli, E, Di Cesare Mannelli, L, Salvicchi, A, Bartolini, A, Koverech, A, Nicolai, R, Benatti, P, Ghelardini, C

    Published in Neuroscience (02-06-2010)
    “…Abstract Damages to the nervous system are the primarily cause of neuropathy and chronic pain. Current pharmacological treatments for neuropathic pain are not…”
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    Journal Article
  12. 12

    The neuropathy-protective agent acetyl- l -carnitine activates protein kinase C-γ and MAPKs in a rat model of neuropathic pain by Di Cesare Mannelli, L, Ghelardini, C, Toscano, A, Pacini, A, Bartolini, A

    Published in Neuroscience (17-02-2010)
    “…Abstract The γ isoform of protein kinase C (PKCγ) is an injury-activated intracellular modulator that boosts neuronal activity in algesic and neuroregenerative…”
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    Journal Article
  13. 13

    Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs by Guandalini, L., Martini, E., Di Cesare Mannelli, L., Dei, S., Manetti, D., Scapecchi, S., Teodori, E., Ghelardini, C., Romanelli, M.N.

    Published in Bioorganic & medicinal chemistry letters (01-03-2012)
    “…A series of analogs of DM235 and MN19, characterized by rings with different size, have been prepared and evaluated for their nootropic activity in the mouse…”
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    The endoscopic spectrum of segmental colitis associated with diverticulosis by Tursi, A., Elisei, W., Brandimarte, G., Giorgetti, G. M., Lecca, P. G., Di Cesare, L., Inchingolo, C. D., Aiello, F.

    Published in Colorectal disease (01-05-2010)
    “…Objective  An endoscopic classification of ‘Segmental colitis associated with diverticulosis’ (SCAD) is lacking. Our aim was therefore to assess the endoscopic…”
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    Journal Article
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