Search Results - "DI, WENJUAN"

Impact of a high‑fat diet on intestinal stem cells and epithelial barrier function in middle‑aged female mice by Xie, Yu, Ding, Fei, Di, Wenjuan, Lv, Yifan, Xia, Fan, Sheng, Yunlu, Yu, Jing, Ding, Guoxian

“…A high‑fat diet (HFD) or obesity‑promoting diet is closely associated with metabolic diseases and intestinal tumors, particularly in middle‑aged individuals…”
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Early identification of lung cancer patients with venous thromboembolism: development and validation of a risk prediction model by Di, Wenjuan, Xu, Haotian, Ling, Chunhua, Xue, Ting

“…Abstract Introduction Venous thromboembolism(VTE) is a leading cause of death in patients with lung cancer. Furthermore, hospitalization of patients with…”
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Glucocorticoids transcriptionally regulate miR-27b expression promoting body fat accumulation via suppressing the browning of white adipose tissue by Kong, Xiaocen, Yu, Jing, Bi, Jianhua, Qi, Hanmei, Di, Wenjuan, Wu, Lin, Wang, Long, Zha, Juanmin, Lv, Shan, Zhang, Feng, Li, Yan, Hu, Fang, Liu, Feng, Zhou, Hong, Liu, Juan, Ding, Guoxian

“…Long-term glucocorticoid (GC) treatment induces central fat accumulation and metabolic dysfunction. We demonstrate that microRNA-27b (miR-27b) plays a central…”
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MiR-27b-3p Inhibition Enhances Browning of Epididymal Fat in High-Fat Diet Induced Obese Mice by Yu, Jing, Lv, Yifan, Wang, Fengliang, Kong, Xiaocen, Di, Wenjuan, Liu, Juan, Sheng, Yunlu, Lv, Shan, Ding, Guoxian

“…Long-term dysregulation of energy balance is the key component of the obesity epidemic. Given the harm of central obesity and the discovery that beige cells…”
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BVT.2733, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese mice by Wang, Long, Liu, Juan, Zhang, Aisen, Cheng, Peng, Zhang, Xiao, Lv, Shan, Wu, Lin, Yu, Jing, Di, Wenjuan, Zha, Juanmin, Kong, Xiaocen, Qi, Hanmei, Zhong, Yi, Ding, Guoxian

“…Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic…”
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11β-hydroxysteroid dehydrogenase type 1 selective inhibitor BVT.2733 protects osteoblasts against endogenous glucocorticoid induced dysfunction by Wu, Lin, Qi, Hanmei, Zhong, Yi, Lv, Shan, Yu, Jing, Liu, Juan, Wang, Long, Bi, Jianhua, Kong, Xiaocen, Di, Wenjuan, Zha, Juanmin, Liu, Feng, Ding, Guoxian

“…Pharmacologic glucocorticoids (GCs) inhibit osteoblast function and induce osteoporosis. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) may play a role in…”
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Adipose tissue-targeted 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity by Liu, Juan, Wang, Long, Zhang, Aisen, Di, Wenjuan, Zhang, Xiao, Wu, Lin, Yu, Jing, Zha, Juanmin, Lv, Shan, Cheng, Peng, Hu, Miao, Li, Yujie, Qi, Hanmei, Ding, Guoxian, Zhong, Yi

“…Current pharmacological treatments for obesity and metabolic syndrome have various limitations. Recently, adipose tissue 11β-hydroxysteroid dehydrogenase type…”
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11β-hydroxysteroid dehydrogenase type 1 selective inhibitor BVT.2733 protects osteoblasts against endogenous glucocorticoid induced dysfunction by Lin Wu, Hanmei Qi, Yi Zhong, Shan Lv, Jing Yu, Juan Liu, Long Wang, Jianhua Bi, Xiaocen Kong, Wenjuan Di, Juanmin Zha, Feng Liu, Guoxian Ding

“…[Abstract. ] Pharmacologic glucocorticoids (GCs) inhibit osteoblast function and induce osteoporosis. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) may…”
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Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR‐146b‐5p by Di, Wenjuan, Zhang, Wenling, Zhu, Bei, Li, Xiaolin, Tang, Qiyun, Zhou, Yichan

“…Cancer cachexia is a complex syndrome that is associated with thermogenic gene regulation. Currently, although some studies have reported the link between…”
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Long-term exercise-secreted extracellular vesicles promote browning of white adipocytes by suppressing miR-191a-5p by Di, Wenjuan, Amdanee, Nousayhah, Zhang, Wenling, Zhou, Yichan

“…The purpose of the study is to explore the mechanism of transdifferentiation from white adipose tissue (WAT) to Brown adipose tissue (BAT). In this study, we…”
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Adipose tissue-targeted 11.BETA.-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity by Liu, Juan, Wang, Long, Zhang, Aisen, Di, Wenjuan, Zhang, Xiao, Wu, Lin, Yu, Jing, Zha, Juanmin, Lv, Shan, Cheng, Peng, Hu, Miao, Li, Yujie, Qi, Hanmei, Ding, Guoxian, Zhong, Yi

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Opposing effects on cardiac function by calorie restriction in different‐aged mice by Sheng, Yunlu, Lv, Shan, Huang, Min, Lv, Yifan, Yu, Jing, Liu, Juan, Tang, Tingting, Qi, Hanmei, Di, Wenjuan, Ding, Guoxian

“…Summary Calorie restriction (CR) increases average and maximum lifespan and exhibits an apparent beneficial impact on age‐related diseases. Several studies…”
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Measurement of BAT activity by targeted molecular magnetic resonance imaging by Hu, Qingqiao, Cao, Huixiao, Zhou, Lu, Liu, Juan, Di, Wenjuan, Lv, Shan, Ding, Guoxian, Tang, Lijun

“…The aim of this study was to measure brown adipose tissue (BAT) activity by targeted peptide (CKGGRAKDC-NH2)-coupled, polyethylene glycol (PEG)-coated…”
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Improvement of intestinal stem cells and barrier function via energy restriction in middle-aged C57BL/6 mice by Di, Wenjuan, Lv, Yifan, Xia, Fan, Sheng, Yunlu, Liu, Juan, Ding, Guoxian

“…This study aimed to reveal the impact of energy restriction on the intestine via structural and molecular changes in terms of intestinal stem cell (ISC)…”
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11β-hydroxysteroid dehydrogenase type 1 inhibitor attenuates high-fat diet induced cardiomyopathy by Huang, Min, Liu, Juan, Sheng, Yunlu, Lv, Yifan, Yu, Jing, Qi, Hanmei, Di, Wenjuan, Lv, Shan, Zhou, Suming, Ding, Guoxian

“…High-fat diet (HFD) induces cardiac hypertrophy; however, the underlying cellular and molecular mechanisms are yet unclear. In the present study, we…”
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Expression Profiling of PPARγ-Regulated MicroRNAs in Human Subcutaneous and Visceral Adipogenesis in both Genders by Yu, Jing, Kong, Xiaocen, Liu, Juan, Lv, Yifan, Sheng, Yunlu, Lv, Shan, Di, Wenjuan, Wang, Chen, Zhang, Feng, Ding, Guoxian

“…Clinical evidence shows that visceral fat accumulation decreases whereas sc fat increases in patients treated with thiazolidinediones (TZDs), a type of…”
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A High Efficient Method to Isolate Exosomes from Small Intestinal Epithelium by Xia, Fan, Ding, Fei, Lv, Yifan, Di, Wenjuan, Sheng, Yunlu, Ding, Guoxian

“…The intestinal epithelium is an important receptor that is not only exposed to nutrients but also to pathogens, such as ingested toxins, bacterial flora, and…”
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Advances in the Prediction and Risk Assessment of Lung Cancer-Associated Venous Thromboembolism by Di, Wenjuan, Xu, Haotian, Xue, Ting, Ling, Chunhua

“…According to the most recent data from the National Cancer Center, venous thromboembolism (VTE) has unsurprisingly become one of the most common complications…”
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Assessment of Fat distribution and Bone quality with Trabecular Bone Score (TBS) in Healthy Chinese Men by Lv, Shan, Zhang, Aisen, Di, Wenjuan, Sheng, Yunlu, Cheng, Peng, Qi, Hanmei, Liu, Juan, Yu, Jing, Ding, Guoxian, Cai, Jinmei, Lai, Bin

“…Whether fat is beneficial or detrimental to bones is still controversial, which may be due to inequivalence of the fat mass. Our objective is to define the…”
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MiR‐27b‐3p Regulation in Browning of Human Visceral Adipose Related to Central Obesity by Yu, Jing, Lv, Yifan, Di, Wenjuan, Liu, Juan, Kong, Xiaocen, Sheng, Yunlu, Huang, Min, Lv, Shan, Qi, Hanmei, Gao, Mei, Liang, Hui, Kim, Sarah, Fu, Zan, Zhou, Hong, Ding, Guoxian

“…Objective Given the rising prevalence of central obesity and the discovery that beige cells appear within white adipose tissue, strategies to enhance these…”
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