Search Results - "DHALLA, N S"

Status of myocardial antioxidants in ischemia-reperfusion injury by DHALLA, N. S, ELMOSELHI, A. B, HATA, T, MAKINO, N

“…Myocardial ischemia-reperfusion represents a clinically relevant problem associated with thrombolysis, angioplasty and coronary bypass surgery. Injury of…”
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Role of oxidative stress in cardiovascular diseases by Dhalla, Naranjan S, Temsah, Rana M, Netticadan, Thomas

“…OBJECTIVESIn view of the critical role of intracellular Ca-overload in the genesis of myocyte dysfunction and the ability of reactive oxygen species (ROS) to…”
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Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload by Dent, Melissa R., Aroutiounova, Nina, Dhalla, N. S., Tappia, P. S.

“…Because the left ventricular (LV) hypertrophy due to volume overload induced by arteriovenous (AV) shunt was associated with an increase in phospholipase C…”
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Neurohormones and oxidative stress in nonischemic cardiomyopathy: relationship to survival and the effect of treatment with amlodipine by Wijeysundera, H.C, Hansen, M.S, Stanton, E, Cropp, A.S, Hall, C, Dhalla, N.S, Ghali, J, Rouleau, J.L

“…The purpose of this study was to assess the effects of amlodipine on neurohormones and oxidative stress in nonischemic cardiomyopathy, and determine the…”
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Prognostic importance of the oxidized product of catecholamines, adrenolutin, in patients with severe heart failure by Rouleau, J.L, Pitt, B, Dhalla, N.S, Dhalla, K.S, Swedberg, K, Hansen, M.S, Stanton, E, Lapointe, N, Packer, M

“…The purpose of this study was to assess whether adrenolutin, the inert product of the highly reactive molecules aminochromes, is increased in severe chronic…”
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Differential changes in left and right ventricular SR calcium transport in congestive heart failure by Afzal, N, Dhalla, N S

“…To examine the status of sarcoplasmic reticulum (SR) with respect to Ca2+ transport in congestive heart failure due to myocardial infarction, the left coronary…”
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Sarcolemmal Na(+)-K(+)-ATPase activity in congestive heart failure due to myocardial infarction by Dixon, I M, Hata, T, Dhalla, N S

“…Because the Na+ pump is considered to modulate the contractile force development by the cardiac muscle and depressed cardiac pump function is the hallmark of…”
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Phosphatidic acid increases intracellular free Ca2+ and cardiac contractile force by Xu, Y J, Panagia, V, Shao, Q, Wang, X, Dhalla, N S

“…Although phosphatidic acid (PA) is mainly formed due to the hydrolysis of phosphatidylcholine by myocardial phospholipase D, its functional significance in the…”
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Structure-function relationships and modifications of cardiac sarcoplasmic reticulum Ca2+-transport by Nusier, M, Shah, A K, Dhalla, N S

“…Sarcoplasmic reticulum (SR) is a specialized tubular network, which not only maintains the intracellular concentration of Ca2+ at a low level but is also known…”
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Differential changes in left and right ventricular adenylyl cyclase activities in congestive heart failure by Sethi, R, Dhalla, K S, Beamish, R E, Dhalla, N S

“…The status of beta-adrenergic receptors and adenylyl cyclase in crude membranes from both left and right ventricles was examined when the left coronary artery…”
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Sarcolemmal calcium transport in congestive heart failure due to myocardial infarction in rats by Dixon, I M, Hata, T, Dhalla, N S

“…Because Na(+)-Ca2+ exchange and Ca2+ pump are thought to play a role in sarcolemmal Ca2+ movements, we examined the Na(+)-dependent Ca(2+)-uptake and…”
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Cardioprotective effects of cysteine alone or in combination with taurine in diabetes by Tappia, P S, Xu, Y-J, Rodriguez-Leyva, D, Aroutiounova, N, Dhalla, N S

“…This study was undertaken to examine the effects of dietary supplementation of cysteine and taurine in rats with diabetes induced with streptozotocin (STZ, 65…”
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Anti-atherosclerotic molecules targeting oxidative stress and inflammation by Adameova, A, Xu, Y J, Duhamel, T A, Tappia, P S, Shan, L, Dhalla, N S

“…The accumulation of lipids within arteries remains to be the initial impulse for the pathogenesis of atherosclerosis; however, both inflammation and oxidative…”
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Nitrendipine Binding in Congestive Heart Failure Due to Myocardial Infarction by Dixon, Ian M.C, Lee, Sheu-Lun, Dhalla, Naranjan S

“…Depressed cardiac pump function is the hallmark of congestive heart failure, and it is suspected that decreased influx of Ca into the cardiac cell is…”
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Role of extracellular matrix proteins in heart function by PELOUCH, V, DIXON, I. M. C, GOLFMAN, L, BEAMISH, R. E, DHALLA, N. S

“…The cardiac interstitium is populated by nonmyocyte cell types including transcriptionally active cardiac fibroblasts and endothelial cells. Since these cells…”
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Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathy by Ganguly, P K, Pierce, G N, Dhalla, K S, Dhalla, N S

“…The effects of insulin and thyroid hormone treatments on cardiac sarcoplasmic reticular function were investigated in chronic streptozotocin-induced diabetes…”
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Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation by Xu, Y.‐J., Chapman, D., Dixon, I. M.C., Sethi, R., Guo, X., Dhalla, N. S.

“…Post‐myocardial infarction (MI) remodeling of cardiac myocytes and the myocardial interstitium results in alteration of gross ventricular geometry and…”
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Modulation of cardiac sarcoplasmic reticulum gene expression by lack of oxygen and glucose by Temsah, Rana M., Kawabata, Kenichi, Chapman, Donald, Dhalla, Naranjan S.

“…ABSTRACT Although ischemia reperfusion has been shown to depress gene expression of the sarcoplasmic reticulum (SR) proteins, such as the ryanodine receptor,…”
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Na+-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats by Pierce, G.N. (University of Manitoba, Winnipeg, Manitoba, Canada), Ramjiawan, B, Dhalla, N.S, Ferrari, R

“…Intracellular pH and [Na+] in the heart are regulated by the sarcolemmal membrane Na(+)-H+ exchange pathway. No data are currently available regarding the…”
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Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction by Ganguly, Pallab K., Dhalla, Ken S., Shao, Qiming, Beamish, Robert E., Dhalla, Naranjan S.

“…Although congestive heart failure subsequent to myocardial infarction is known to be associated with increased sympathetic activity, very little information…”
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