Search Results - "DEXTER, L"

The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs by Puckett, Dexter L, Alquraishi, Mohammed, Chowanadisai, Winyoo, Bettaieb, Ahmed

“…Pyruvate kinase is a key regulator in glycolysis through the conversion of phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms…”
Get full text

Pyruvate kinase M2: A simple molecule with complex functions by Alquraishi, Mohammed, Puckett, Dexter L., Alani, Dina S., Humidat, Amal S., Frankel, Victoria D., Donohoe, Dallas R., Whelan, Jay, Bettaieb, Ahmed

“…Pyruvate kinase M2 is a critical enzyme that regulates cell metabolism and growth under different physiological conditions. In its metabolic role, pyruvate…”
Get full text

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase by Han, SeungHye, Lear, Travis B., Jerome, Jacob A., Rajbhandari, Shristi, Snavely, Courtney A., Gulick, Dexter L., Gibson, Kevin F., Zou, Chunbin, Chen, Bill B., Mallampalli, Rama K.

“…The inflammasome is a multiprotein complex that augments the proinflammatory response by increasing the generation and cellular release of key cytokines…”
Get full text

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice by Fan, Ming-Hui, Zhu, Qiang, Li, Hui-Hua, Ra, Hyun-Jeong, Majumdar, Sonali, Gulick, Dexter L., Jerome, Jacob A., Madsen, Daniel H., Christofidou-Solomidou, Melpo, Speicher, David W., Bachovchin, William W., Feghali-Bostwick, Carol, Puré, Ellen

“…Idiopathic pulmonary fibrosis is a disease characterized by progressive, unrelenting lung scarring, with death from respiratory failure within 2–4 years unless…”
Get full text

Group Housing of Male Mice Causes a Significant Decrease in Day to Night Changes in Mean Arterial Pressure and are Indicative of the Development of Hypertension and Cardiovascular Disease by Brown, Nina C., Sampson, Austin C., Richardson, Kimberlei, Lee, Dexter L.

“…Changes in day to night time mean arterial pressure (MAP) predict hypertension and cardiovascular diseases. When there is a decrease in day ‐ night time MAP…”
Get full text

Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity by Bednash, Joseph S., Weathington, Nathaniel, Londino, James, Rojas, Mauricio, Gulick, Dexter L., Fort, Robert, Han, SeungHye, McKelvey, Alison C., Chen, Bill B., Mallampalli, Rama K.

“…Inflammasomes regulate innate immune responses by facilitating maturation of inflammatory cytokines, interleukin (IL)-1β and IL-18. NACHT, LRR and PYD…”
Get full text

PPAR-α knockout leads to elevated blood pressure response to angiotensin II infusion associated with an increase in renal α-1 Na+/K+ ATPase protein expression and activity by Khundmiri, Syed J., Ecelbarger, Carolyn M., Amponsem, Joycemary, Ji, Hong, Sandberg, Kathryn, Lee, Dexter L.

“…Peroxisome proliferator activated receptor alpha (PPAR-α) deletion has been shown to increase blood pressure (BP). We hypothesized that the BP increase in…”
Get full text

Chronic use of benzodiazepines: The problem that persists by Louie, Dexter L, Jegede, Oluwole O, Hermes, Gretchen L

“…Though clinical guidelines and policies discourage the chronic prescribing of benzodiazepines, rates of prescribing have continued to rise in the United States…”
Get full text

Learning from HBCUs: How to produce Black professionals in STEMM by Shuler, Haysetta D., Spencer, Elsie C., Davis, Jamaine S., Damo, Steven, Shakespeare, Teresa I., Murray, Sandra A., Lee, Dexter L., Hinton, Antentor

“…Historically Black colleges and universities (HBCUs) offer high-quality education and produce leaders from various backgrounds, mainly being African American…”
Get full text

The Application of Historic Building Information Modelling (HBIM) to Cultural Heritage: A Review by Lovell, Lucy J., Davies, Richard J., Hunt, Dexter V. L.

“…Historic Building Information Modelling (HBIM) is the application of BIM, a digital modelling and information management technique, to assets of historical…”
Get full text

Post-translational modification of the interferon-gamma receptor alters its stability and signaling by Londino, James D, Gulick, Dexter L, Lear, Travis B, Suber, Tomeka L, Weathington, Nathaniel M, Masa, Luke S, Chen, Bill B, Mallampalli, Rama K

“…The IFN gamma receptor 1 (IFNGR1) binds IFN-γ and activates gene transcription pathways crucial for controlling bacterial and viral infections. Although…”
Get more information

SARS-CoV-2 Infection and Racial Disparities in Children: Protective Mechanisms and Severe Complications Related to MIS-C by Kurup, Sanjana, Burgess, Regan, Tine, Fatou, Chahroudi, Ann, Lee, Dexter L.

“…A novel coronavirus has resulted in a pandemic with over 176 million confirmed cases and over 3.8 million recorded deaths. In the USA, SARS-CoV-2 infection has…”
Get full text

Risk factors for persistent abnormality on chest radiographs at 12-weeks post hospitalisation with PCR confirmed COVID-19 by Wallis, T. J. M, Heiden, E, Horno, J, Welham, B, Burke, H, Freeman, A, Dexter, L, Fazleen, A, Kong, A, McQuitty, C, Watson, M, Poole, S, Brendish, N. J, Clark, T. W, Wilkinson, T. M. A, Jones, M. G, Marshall, B. G

“…Background The long-term consequences of COVID-19 remain unclear. There is concern a proportion of patients will progress to develop pulmonary fibrosis. We…”
Get full text

Psychiatric Agnosticism and the Pedagogical Problem of Learning Psychiatry as a Medical Student by Louie, Dexter L.

“…In my understanding of her thinking, our patient’s disease was a clinical syndrome generated by a pathological process, as opposed to an outcome of a traumatic…”
Get full text

HPV vaccine awareness and the association of trust in cancer information from physicians among males by Cooper, Dexter L, Hernandez, Natalie D, Rollins, Latrice, Akintobi, Tabia Henry, McAllister, Calvin

“…Highlights • About half of the all-male sample had never heard of HPV. • Black men were the least likely to know that HPV is transmitted sexually. • Hispanic…”
Get full text

544 Interleukin-6 protects renal dysfunction in mouse models of hypertension and salt-sensitive hypertension by Hatcher, Mark D., Duan, Rong, Lee, Dexter L.

“…OBJECTIVES/GOALS: We are investigating the role of IL-6 in regulating renal function by measuring mean arterial pressure (MAP), renal plasma flow (RPF) and…”
Get full text

The effect of Ramadan fasting during pregnancy on perinatal outcomes: a systematic review and meta-analysis by Glazier, Jocelyn D, Hayes, Dexter J L, Hussain, Sabiha, D'Souza, Stephen W, Whitcombe, Joanne, Heazell, Alexander E P, Ashton, Nick

“…Although exempt, many pregnant Muslim women partake in the daily fast during daylight hours during the month of Ramadan. In other contexts an impoverished diet…”
Get full text

"RUN, JUMP, OR SHUFFLE ARE ALL THE SAME WHEN YOU DO IT FOR THE MAN!": The OPHR, Black Power, and the Boycott of the 1968 NYAC Meet by Blackman, Dexter L.

“…The article examines black activists' use of sports and protest in the 1960s to elaborate on the meaning of black advancement in the period, especially Black…”
Get full text

Supporting and promoting Black physiologists: how can the APS help? by Robinson, Austin T, Jenkins, Nathaniel D M, Sanchez, Sofia O, Haack, Karla K V, Lee, Dexter L, Mathis, Keisa W, Warrington, Junie P

Get more information

Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B by Inman, Martyn, Dexter, Hannah L, Moody, Christopher J

“…The cyclic dodecapeptides wewakazole and wewakazole B have been synthesized by a divergent strategy via a common tris-proline containing oxazole octapeptide…”
Get full text