Search Results - "DEXI LIU"

Chlorogenic Acid Improves High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice by Ma, Yongjie, Gao, Mingming, Liu, Dexi

“…ABSTRACT Purpose Chlorogenic acid (CGA), the most abundant component in coffee, has exhibited many biological activities. The objective of this study is to…”
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Development of novel SARS-CoV-2 viral vectors by Liu, Huan, Liu, Dexi

“…The authentic SARS-CoV-2 requires to be handled in Biosafety Level 3 laboratories, which restrains investigation by the broader scientific community. Here, we…”
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High-fat diet-induced adiposity, adipose inflammation, hepatic steatosis and hyperinsulinemia in outbred CD-1 mice by Gao, Mingming, Ma, Yongjie, Liu, Dexi

“…High-fat diet (HFD) has been applied to a variety of inbred mouse strains to induce obesity and obesity related metabolic complications. In this study, we…”
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Rutin Suppresses Palmitic Acids-Triggered Inflammation in Macrophages and Blocks High Fat Diet-Induced Obesity and Fatty Liver in Mice by Gao, Mingming, Ma, Yongjie, Liu, Dexi

“…Purpose To elucidate the mechanism of rutin in blocking macrophage-mediated inflammation and high fat diet-induced obesity and fatty liver. Methods Both in…”
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Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer by Ma, Yongjie, Gao, Mingming, Liu, Dexi

“…Neuregulin 4 (NRG4), an epidermal growth factor-like signaling molecule, plays an important role in cell-to-cell communication during tissue development. Its…”
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Flexible and transparent films consisting of lanthanide complexes for ratiometric luminescence thermometry by Yang, Daqing, Liu, Dexi, Tian, Chunkun, Wang, Song, Li, Huanrong

“…[Display omitted] Herein, a flexible and transparent film consisting Eu3+/Tb3+ lanthanide complexes and poly(methylmethacrylate) was constructed via solution…”
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CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice by Gao, Mingming, Liu, Dexi

“…Both Pten and Nras are downstream mediators of receptor tyrosine kinase activation that plays important roles in controlling cell survival and proliferation…”
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Phloretin Prevents High-Fat Diet-Induced Obesity and Improves Metabolic Homeostasis by Alsanea, Sary, Gao, Mingming, Liu, Dexi

“…Reactive oxygen species generated as a by-product in metabolism play a central role in the development of obesity and obesity-related metabolic complications…”
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Development of a multiple cross displacement amplification combined with nanoparticles-based biosensor assay for rapid and sensitive detection of Streptococcus pyogenes by Dou, Zhiqian, Xie, Ling, Gao, Meiling, Liu, Dexi

“…S. pyogenes, is a primary pathogen that leads to pharyngitis and can also trigger severe conditions like necrotizing fasciitis and streptococcal toxic shock…”
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Transcription Factor Binding Site in Promoter Determines the Pattern of Plasmid-Based Transgene Expression In Vivo by Zhang, Chunbo, Liu, Dexi

“…Understanding the regulation of transgene expression is critical for the success of plasmid-based gene therapy and vaccine development. In this study, we used…”
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Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance by Ma, Yongjie, Huang, Yixian, Yan, Linna, Gao, Mingming, Liu, Dexi

“…ABSTRACT Purpose To examine the effect of farnesoid X receptor (FXR) activation by its synthetic agonist,…”
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The Liver X Receptor Agonist T0901317 Protects Mice from High Fat Diet-Induced Obesity and Insulin Resistance by Gao, Mingming, Liu, Dexi

“…The effect of activation of liver X receptor by N -(2,2,2-trifluoroethyl)- N -[4-[2,2,2-trifluoro-1-hydroxy-1(trifluoromethyl)ethyl]phenyl] benzenesulfonamide…”
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Activation of pregnane X receptor by pregnenolone 16 α-carbonitrile prevents high-fat diet-induced obesity in AKR/J mice by Ma, Yongjie, Liu, Dexi

“…Pregnane X receptor (PXR) is known to function as a xenobiotic sensor to regulate xenobiotic metabolism through selective transcription of genes responsible…”
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Dual Outcomes of Rosiglitazone Treatment on Fatty Liver by Gao, Mingming, Ma, Yongjie, Alsaggar, Mohammad, Liu, Dexi

“…In previous studies, it has been reported that rosiglitazone has opposing effects on nonalcoholic fatty liver disease. The purpose of the current study is to…”
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Concurrent activation of liver X receptor and peroxisome proliferator-activated receptor alpha exacerbates hepatic steatosis in high fat diet-induced obese mice by Gao, Mingming, Bu, Le, Ma, Yongjie, Liu, Dexi

“…Liver X receptor (LXR) activation improves glucose homeostasis in obesity. This improvement, however, is associated with several side effects including…”
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Histone deacetylase inhibitors reactivate silenced transgene in vivo by Zhang, Chunbo, Zhang, Guisheng, Liu, Dexi

“…Gene silencing for plasmid-based vectors and the underlying mechanism are critical factors for development of effective gene therapy. The objective of this…”
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Structural and electrochromic property control of WO3 films through fine-tuning of film-forming parameters by Lin, Gai, Li, Xiaobo, Liu, Dexi, Jiao, Zibao, Liu, Peijiang

“…Tungsten trioxide (WO ) films, extensively investigated for their remarkable electrochromic properties, have proven to be highly versatile in numerous…”
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Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice by Lu, Bingxin, Zhong, Jianing, Pan, Jianfei, Yuan, Xiaopeng, Ren, Mingzhi, Jiang, Liping, Yang, Yuqing, Zhang, Guisheng, Liu, Dexi, Zhang, Chunbo

“…The growth differentiation factor 11 (GDF11) was shown to reverse age-related hypertrophy on cardiomyocytes and considered as anti-aging rejuvenation factor…”
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Hydrodynamic Delivery of mIL10 Gene Protects Mice From High-fat Diet-induced Obesity and Glucose Intolerance by Gao, Mingming, Zhang, Chunbo, Ma, Yongjie, Bu, Le, Yan, Linna, Liu, Dexi

“…High-fat diet (HFD) induced obesity is associated with low-grade inflammation, insulin resistance (IR), and glucose intolerance. The objective of this study is…”
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Computer-assisted Hydrodynamic Gene Delivery by Suda, Takeshi, Suda, Kieko, Liu, Dexi

“…The recently developed hydrodynamic delivery method makes it possible to deliver DNA and RNA into parenchyma cells by intravascular injection of nucleic…”
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