Search Results - "DEWAR, John A"

Fulvestrant 500 mg Versus Anastrozole 1 mg for the First-Line Treatment of Advanced Breast Cancer: Overall Survival Analysis From the Phase II FIRST Study by Ellis, Matthew J, Llombart-Cussac, Antonio, Feltl, David, Dewar, John A, Jasiówka, Marek, Hewson, Nicola, Rukazenkov, Yuri, Robertson, John F R

“…To compare overall survival (OS) for fulvestrant 500 mg versus anastrozole as first-line endocrine therapy for advanced breast cancer. The Fulvestrant…”
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The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials by Haviland, Joanne S, MSc, Owen, J Roger, FRCR, Dewar, John A, Prof, Agrawal, Rajiv K, FRCR, Barrett, Jane, FRCR, Barrett-Lee, Peter J, Prof, Dobbs, H Jane, FRCR, Hopwood, Penelope, MD, Lawton, Pat A, PhD, Magee, Brian J, FRCR, Mills, Judith, MPhil, Simmons, Sandra, Sydenham, Mark A, BSc, Venables, Karen, PhD, Bliss, Judith M, Prof, Yarnold, John R, Prof

“…Summary Background 5-year results of the UK Standardisation of Breast Radiotherapy (START) trials suggested that lower total doses of radiotherapy delivered in…”
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Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial by Vaidya, Jayant S, Prof, Wenz, Frederik, Prof, Bulsara, Max, Prof, Tobias, Jeffrey S, Prof, Joseph, David J, Prof, Keshtgar, Mohammed, Prof, Flyger, Henrik L, MD, Massarut, Samuele, MD, Alvarado, Michael, MD, Saunders, Christobel, Prof, Eiermann, Wolfgang, Prof, Metaxas, Marinos, PhD, Sperk, Elena, MD, Sütterlin, Marc, Prof, Brown, Douglas, FRCS, Esserman, Laura, Prof, Roncadin, Mario, MD, Thompson, Alastair, Prof, Dewar, John A, Prof, Holtveg, Helle M R, MD, Pigorsch, Steffi, MD, Falzon, Mary, FRCPath, Harris, Eleanor, MD, Matthews, April, BSc, Brew-Graves, Chris, MSc, Potyka, Ingrid, PhD, Corica, Tammy, BSc, Williams, Norman R, PhD, Baum, Michael, Prof

“…Summary Background The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated…”
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Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial by Hadad, Sirwan, Iwamoto, Takayuki, Jordan, Lee, Purdie, Colin, Bray, Susan, Baker, Lee, Jellema, Gera, Deharo, Steve, Hardie, D. Grahame, Pusztai, Lajos, Moulder-Thompson, Stacy, Dewar, John A., Thompson, Alastair M.

“…Metformin may reduce the incidence of breast cancer and enhance response to neoadjuvant chemotherapy in diabetic women. This trial examined the effects of…”
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Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS) by Thompson, Alastair M, Jordan, Lee B, Quinlan, Philip, Anderson, Elizabeth, Skene, Anthony, Dewar, John A, Purdie, Colin A

“…Immunohistochemistry of primary breast cancer is routinely used to guide changes in therapy at the time of relapse. Retrospective reviews suggest that the…”
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Differential Contextual Responses of Normal Human Breast Epithelium to Ionizing Radiation in a Mouse Xenograft Model by COATES, Philip J, APPLEYARD, M. Virginia C. L, WRIGHT, Eric G, DEWAR, John A, THOMPSON, Alastair M, MURRAY, Karen, ACKLAND, Caroline, GARDNER, June, BROWN, Douglas C, ADAMSON, Dougal J. A, JORDAN, Lee B, PURDIE, Colin A, MUNRO, Alastair J

“…Radiotherapy is a key treatment option for breast cancer, yet the molecular responses of normal human breast epithelial cells to ionizing radiation are…”
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Importance of long-term follow-up of women receiving adjuvant therapy for breast cancer in the community by McCowan, Colin, Dewar, John A, Thompson, Alastair M

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A study to evaluate nurse-led on-treatment review for patients undergoing radiotherapy for head and neck cancer by Wells, Mary, Donnan, Peter T, Sharp, Lena, Ackland, Caroline, Fletcher, Janice, Dewar, John A

“…Aims and objectives.  To evaluate a nurse‐led clinic for patients undergoing radiotherapy to the head and neck. Background.  The side effects of radiotherapy…”
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Managing metastatic bone pain by Dewar, John A

“…Radiotherapy and bisphosphonates are effective for metastases and pain…”
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A comparison of systemic breast cancer therapy utilization in Canada (British Columbia), Scotland (Dundee), and Australia (Western Australia) with models of “optimal” therapy by Fong, Andrew, Shafiq, Jesmin, Saunders, Christobel, Thompson, Alastair, Tyldesley, Scott, Olivotto, Ivo A, Barton, Michael B, Dewar, John A, Jacob, Susannah, Ng, Weng, Speers, Caroline, Delaney, Geoff P

“…Abstract Background Different jurisdictions report different breast cancer treatment rates. Evidence-based optimal utilization models may be specific to the…”
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Topoisomerase IIα levels and G2 radiosensitivity in T-lymphocytes of women presenting with breast cancer by BRYANT, Peter E, RICHES, Andrew C, SHOVMAN, Olga, DEWAR, John A, ADAMSON, Douglas J. A

“…Previous studies from our laboratory have identified a link between intracellular topoisomerase IIα (topo IIα) levels and chromosomal radiosensitivity, as…”
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Beware using secular trends in deaths to judge effectiveness of breast screening by Brewster, David H, Bhatti, Lesley A, Thomson, Catherine S, Cameron, David A, Dewar, John A

“…Percentage of women with breast cancer in Scotland receiving treatment, by age group, 1997-2011 Our analysis confirms the perception, and the findings of…”
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Megestrol acetate therapy and secondary adrenal suppression by Naing, Ko K., Dewar, John A., Leese, Graham P.

“…BACKGROUND Adrenal suppression has been noted in patients who are receiving medroxyprogesterone acetate (MPA). Megestrol acetate (MA) is used to treat patients…”
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Managing Metastatic Bone Pain: Radiotherapy And Bisphosphonates Are Effective For Metastases And Pain by Dewar, John A.

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A mathematical model for the effect of a false-negative sentinel node biopsy on breast cancer mortality: a tool for everyday use by Vaidya, Jayant S, Dewar, John A, Brown, Douglas C, Thompson, Alastair M

“…One of the concerns of using sentinel node biopsy (SNB) is the risks of a false-negative result (FNR). We have created a mathematical model to estimate the…”
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Correlation of the clinical response to chemotherapy in breast cancer with ex vivo chemosensitivity by Cree, I A, Kurbacher, C M, Untch, M, Sutherland, L A, Hunter, E M, Subedi, A M, James, E A, Dewar, J A, Preece, P E, Andreotti, P E, Bruckner, H W

“…Chemotherapy for breast cancer is given on the basis of empirical information from clinical trials, an approach which falls to take into account the known…”
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Offering informed choice about breast screening by Forbes, Lindsay J L, Ramirez, Amanda-Jane

“…Over the last few years, there has been growing international concern about the risk of overdiagnosis in breast screening and about how to communicate this to…”
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aTTom: Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years in 6,953 women with early breast cancer by Gray, Richard G., Rea, Daniel, Handley, Kelly, Bowden, Sarah Jane, Perry, Philip, Earl, Helena Margaret, Poole, Christopher John, Bates, Tom, Chetiyawardana, Shan, Dewar, John A., Fernando, Indrajit Nalinika, Grieve, Robert, Nicoll, Jonathan, Rayter, Zenor, Robinson, Anne, Salman, Asad, Yarnold, John, Bathers, Sarah, Marshall, Andrea, Lee, Martin

“…Abstract only 5 Background: In estrogen-receptor-positive (ER+) early breast cancer, 5 years of tamoxifen reduces breast cancer death rates by about a third…”
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aTTom: Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years in 6,953 women with early breast cancer by Gray, Richard G., Rea, Daniel, Handley, Kelly, Bowden, Sarah Jane, Perry, Philip, Earl, Helena Margaret, Poole, Christopher John, Bates, Tom, Chetiyawardana, Shan, Dewar, John A., Fernando, Indrajit Nalinika, Grieve, Robert, Nicoll, Jonathan, Rayter, Zenor, Robinson, Anne, Salman, Asad, Yarnold, John, Bathers, Sarah, Marshall, Andrea, Lee, Martin

“…Abstract only 5 The full, final text of this abstract will be available at abstract.asco.org at 7:30 AM (EDT) on Sunday, June, 2, 2013, and in the Annual…”
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Beware using secular trends in deaths to judge effectiveness by Brewster, David H, Bhatti, Lesley A, Thomson, Catherine S, Cameron, David A, Dewar, John A

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