Search Results - "DEVOR, D. C"

Pharmacology of CFTR Chloride Channel Activity by SCHULTZ, B. D, SINGH, A. K, DEVOR, D. C, BRIDGES, R. J

“…B. D. SCHULTZ , A. K. SINGH , D. C. DEVOR , AND R. J. BRIDGES University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Schultz, B. D., A. K…”
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Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel by Devor, D C, Singh, A K, Frizzell, R A, Bridges, R J

“…We evaluated the effects of the novel benzimidazolone, 1-ethyl-2-benzimidazolinone (1-EBIO), on Cl- secretion across T84 monolayers. 1-EBIO stimulated a…”
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Inhibition of intestinal Cl- secretion by clotrimazole: direct effect on basolateral membrane K+ channels by Devor, D C, Singh, A K, Gerlach, A C, Frizzell, R A, Bridges, R J

“…We evaluated the effects of clotrimazole and clofibrate on Ca(2+)- and adenosine 3',5'-cyclic monophosphate (cAMP)-mediated Cl- secretion in the colonic cell…”
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Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor by Kakar, S S, Musgrove, L C, Devor, D C, Sellers, J C, Neill, J D

“…Gonadotropin releasing hormone is a hypothalamic decapeptide that stimulates the release of gonadotropic hormones from the anterior pituitary gland…”
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Angiotensin II type-1 receptor subtype cDNAs: differential tissue expression and hormonal regulation by Kakar, S S, Sellers, J C, Devor, D C, Musgrove, L C, Neill, J D

“…A rat angiotensin, type 1A (AT1A) receptor cDNA was cloned recently and shown to be a member of the 7-transmembrane, G-protein coupled family of receptors…”
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Calcium-mediated agonists activate an inwardly rectified K+ channel in colonic secretory cells by Devor, D C, Frizzell, R A

“…Single-channel recording techniques were used to identify and characterize the K+ channel activated by Ca(2+)-mediated secretory agonists in T84 cells…”
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Psoralens: novel modulators of Cl- secretion by Devor, D.C. (University of Pittsburgh, Pittsburgh, PA.), Singh, A.K, Bridges, R.J, Frizzell, R.A

“…We evaluated effects of psoralens on Cl- secretion (short-circuit current, Isc) across T84 monolayers. Methoxsalen failed to increase Isc. Several observations…”
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Epitope tagging permits cell surface detection of functional CFTR by Howard, M, DuVall, M D, Devor, D C, Dong, J Y, Henze, K, Frizzell, R A

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is a phosphorylation-activated Cl channel responsible for adenosine 3',5'-cyclic monophosphate…”
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Vasoactive intestinal peptide-stimulated Cl- secretion: activation of cAMP-dependent K+ channels by Izu, L T, McCulle, S L, Ferreri-Jacobia, M T, Devor, D C, Duffey, M E

“…Vasoactive intestinal peptide (VIP) stimulates active Cl- secretion by the intestinal epithelium, a process that depends upon the maintenance of a favorable…”
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cAMP-activated Cl- channels in primary cultures of spiny dogfish (Squalus acanthias) rectal gland by Devor, D C, Forrest, Jr, J N, Suggs, W K, Frizzell, R A

“…Whole cell and single-channel patch-clamp techniques were used to identify and characterize the Cl- currents responsible for adenosine 3',5'-cyclic…”
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Carbachol induces K+, Cl-, and nonselective cation conductances in T84 cells: a perforated patch-clamp study by Devor, D C, Duffey, M E

“…We used the perforated patch-clamp technique to examine cell membrane ionic conductances in isolated cells of the human colonic secretory cell line, T84,…”
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Carbachol induces oscillations of membrane potassium conductance in a colonic cell line, T84 by Devor, D C, Simasko, S M, Duffey, M E

“…Effects of carbachol on membrane potential and current in T84 cells were determined using whole cell patch-clamp techniques. When the pipettes contained a…”
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Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84) by DEVOR, D. C, CHANDRA SEKAR, M, FRIZZELL, R. A, DUFFEY, M. E

“…Whole-cell patch-clamp techniques and fluorescence measurements of intracellular Ca2+ concentration, (Ca2+)i, were used to investigate the mechanism of…”
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Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells by Devor, D C, Singh, A K, Lambert, L C, DeLuca, A, Frizzell, R A, Bridges, R J

“…Serous cells are the predominant site of cystic fibrosis transmembrane conductance regulator expression in the airways, and they make a significant…”
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Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease by Singh, S, Syme, C A, Singh, A K, Devor, D C, Bridges, R J

“…The diseases of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are characterized by mucus-congested airways. Agents that stimulate the…”
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Modulation of Cl- secretion by benzimidazolones. II. Coordinate regulation of apical GCl and basolateral GK by Devor, D C, Singh, A K, Bridges, R J, Frizzell, R A

“…We previously demonstrated that the novel benzimidazolone, 1-ethyl-2-benzimidazolinone (1-EBIO), stimulates a sustained Cl- secretory response across T84…”
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Kinase-dependent Regulation of the Intermediate Conductance, Calcium-dependent Potassium Channel, hIK1 by Gerlach, A C, Gangopadhyay, N N, Devor, D C

“…We determined the effect of nucleotides and protein kinase A (PKA) on the Ca 2+ -dependent gating of the cloned intermediate conductance, Ca 2+ -dependent K +…”
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Intracellular pH and membrane potassium conductance in rabbit distal colon by Duffey, M E, Devor, D C

“…Intracellular pH (pHc) was measured in the short-circuited epithelium of rabbit distal colon using H(+)-selective microelectrodes. pHc was 6.91 +/- 0.02 (SE)…”
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Molecular Localization of the Inhibitory Arachidonic Acid Binding Site to the Pore of hIK1 by Hamilton, Kirk L., Syme, Colin A., Devor, Daniel C.

“…We previously demonstrated that the endogenously expressed human intermediate conductance, Ca2+-activated K+ channel (hIK1) was inhibited by arachidonic acid…”
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Na+ transport in normal and CF human bronchial epithelial cells is inhibited by BAY 39-9437 by Bridges, R J, Newton, B B, Pilewski, J M, Devor, D C, Poll, C T, Hall, R L

“…To test the hypothesis that Na+ transport in human bronchial epithelial (HBE) cells is regulated by a protease-mediated mechanism, we investigated the effects…”
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