Search Results - "DEVELOPMENT"

Third-generation in situ hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust by Choi, Harry M T, Schwarzkopf, Maayan, Fornace, Mark E, Acharya, Aneesh, Artavanis, Georgios, Stegmaier, Johannes, Cunha, Alexandre, Pierce, Niles A

“…hybridization based on the mechanism of the hybridization chain reaction (HCR) has addressed multi-decade challenges that impeded imaging of mRNA expression in…”
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Reactive oxygen species in plant development by Mhamdi, Amna, Van Breusegem, Frank

“…Reactive oxygen species (ROS) are produced by metabolic pathways in almost all cells. As signaling components, ROS are best known for their roles in abiotic…”
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Development of the human placenta by Turco, Margherita Y, Moffett, Ashley

“…The placenta is essential for normal development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as…”
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Wnt signaling in development and tissue homeostasis by Steinhart, Zachary, Angers, Stephane

“…The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication system that is important for stem cell renewal, cell proliferation…”
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Brain organoids: advances, applications and challenges by Qian, Xuyu, Song, Hongjun, Ming, Guo-Li

“…Brain organoids are self-assembled three-dimensional aggregates generated from pluripotent stem cells with cell types and cytoarchitectures that resemble the…”
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Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain by Obernier, Kirsten, Alvarez-Buylla, Arturo

“…In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SGZ), which are…”
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Brassinosteroid signaling in plant development and adaptation to stress by Planas-Riverola, Ainoa, Gupta, Aditi, Betegón-Putze, Isabel, Bosch, Nadja, Ibañes, Marta, Caño-Delgado, Ana I

“…Brassinosteroids (BRs) are steroid hormones that are essential for plant growth and development. These hormones control the division, elongation and…”
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Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination by Yu, Jason S L, Cui, Wei

“…Phosphatidylinositide 3 kinases (PI3Ks) and their downstream mediators AKT and mammalian target of rapamycin (mTOR) constitute the core components of the…”
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Cytokinin signaling in plant development by Kieber, Joseph J, Schaller, G Eric

“…The phytohormone cytokinin plays diverse roles in plant development, influencing many agriculturally important processes, including growth, nutrient responses…”
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Retinoic acid signaling pathways by Ghyselinck, Norbert B, Duester, Gregg

“…Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA receptors (RARs) that regulate development of chordate animals…”
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Circular RNAs: analysis, expression and potential functions by Barrett, Steven P, Salzman, Julia

“…Just a few years ago, it had been assumed that the dominant RNA isoforms produced from eukaryotic genes were variants of messenger RNA, functioning as…”
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The extracellular matrix in development by Walma, David A Cruz, Yamada, Kenneth M

“…As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides both physical support and signaling regulation to cells. Some ECM…”
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The maternal-to-zygotic transition revisited by Vastenhouw, Nadine L, Cao, Wen Xi, Lipshitz, Howard D

“…The development of animal embryos is initially directed by maternal gene products. Then, during the maternal-to-zygotic transition (MZT), developmental control…”
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Adaptation interventions and their effect on vulnerability in developing countries: Help, hindrance or irrelevance? by Eriksen, Siri, Schipper, E. Lisa F., Scoville-Simonds, Morgan, Vincent, Katharine, Adam, Hans Nicolai, Brooks, Nick, Harding, Brian, Khatri, Dil, Lenaerts, Lutgart, Liverman, Diana, Mills-Novoa, Megan, Mosberg, Marianne, Movik, Synne, Muok, Benard, Nightingale, Andrea, Ojha, Hemant, Sygna, Linda, Taylor, Marcus, Vogel, Coleen, West, Jennifer Joy

“…•Adaptation interventions may reinforce, redistribute or create new vulnerability.•Retrofitting adaptation into existing development agendas risks…”
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Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines by Capowski, Elizabeth E, Samimi, Kayvan, Mayerl, Steven J, Phillips, M Joseph, Pinilla, Isabel, Howden, Sara E, Saha, Jishnu, Jansen, Alex D, Edwards, Kimberly L, Jager, Lindsey D, Barlow, Katherine, Valiauga, Rasa, Erlichman, Zachary, Hagstrom, Anna, Sinha, Divya, Sluch, Valentin M, Chamling, Xitiz, Zack, Donald J, Skala, Melissa C, Gamm, David M

“…Numerous protocols have been described for producing neural retina from human pluripotent stem cells (hPSCs), many of which are based on the culture of 3D…”
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Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord by Delile, Julien, Rayon, Teresa, Melchionda, Manuela, Edwards, Amelia, Briscoe, James, Sagner, Andreas

“…The coordinated spatial and temporal regulation of gene expression in the vertebrate neural tube determines the identity of neural progenitors and the function…”
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Neural tube closure: cellular, molecular and biomechanical mechanisms by Nikolopoulou, Evanthia, Galea, Gabriel L, Rolo, Ana, Greene, Nicholas D E, Copp, Andrew J

“…Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular…”
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Vascular endothelial growth factor signaling in development and disease by Karaman, Sinem, Leppänen, Veli-Matti, Alitalo, Kari

“…Vascular endothelial growth factors (VEGFs) are best known for their involvement in orchestrating the development and maintenance of the blood and lymphatic…”
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Cellular senescence in development, regeneration and disease by Rhinn, Muriel, Ritschka, Birgit, Keyes, William M.

“…ABSTRACT Cellular senescence is a state comprising an essentially irreversible proliferative arrest combined with phenotypic changes and pronounced secretory…”
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Gender inequality during the COVID-19 pandemic: Income, expenditure, savings, and job loss by Dang, Hai-Anh H., Viet Nguyen, Cuong

“…•This study examines COVID-19 impacts on gender gaps in economic outcomes.•Women to be 24 percent more likely to permanently lose their job than men.•Women…”
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