Search Results - "DETJEN, K."

Interferon-γ Release Assays Improve the Diagnosis of Tuberculosis and Nontuberculous Mycobacterial Disease in Children in a Country with a Low Incidence of Tuberculosis by Detjen, A. K., Keil, T., Roll, S., Hauer, B., Mauch, H., Wahn, U., Magdorf, K.

“…Background. Diagnosis of childhood tuberculosis (TB) is challenging. The widely used tuberculin skin test (TST) may produce -positive results because of…”
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Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis by Detjen, Anne K, Dr, DiNardo, Andrew R, MD, Leyden, Jacinta, Steingart, Karen R, MD, Menzies, Dick, MD, Schiller, Ian, MSc, Dendukuri, Nandini, PhD, Mandalakas, Anna M, MD

“…Summary Background Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of…”
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Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting by Chegou, Novel N, Detjen, Anne K, Thiart, Lani, Walters, Elisabetta, Mandalakas, Anna M, Hesseling, Anneke C, Walzl, Gerhard

“…The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified…”
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Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis [Review article] by MANDALAKAS, A. M, DETJEN, A. K, HESSELING, A. C, BENEDETTI, A, MENZIES, D

“…BACKGROUND: Children infected with Mycobacterium tuberculosis have significant risk of developing tuberculosis (TB) and can therefore benefit from preventive…”
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Importance of tuberculosis control to address child survival by Graham, Stephen M, Prof, Sismanidis, Charalambos, PhD, Menzies, Heather J, MD, Marais, Ben J, PhD, Detjen, Anne K, MD, Black, Robert E, Prof

“…In the past decade, national tuberculosis programmes in high-burden settings have given increased attention to the challenges of childhood tuberculosis. 2 In…”
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Interferon γ inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis by Detjen, K M, Farwig, K, Welzel, M, Wiedenmann, B, Rosewicz, S

“…BACKGROUND AND AIMS The poor prognosis of pancreatic cancer is partly due to resistance to a broad spectrum of apoptotic stimuli. To identify intact…”
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Provision of Decentralized TB Care Services: A Detect-Treat-Prevent Strategy for Children and Adolescents Affected by TB by Zawedde-Muyanja, Stella, Reuter, Anja, Tovar, Marco A, Hussain, Hamidah, Loando Mboyo, Aime, Detjen, Anne K, Yuen, Courtney M

“…In this review, we discuss considerations and successful models for providing decentralized diagnosis, treatment, and prevention services for children and…”
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The upcoming UN general assembly resolution on tuberculosis must also benefit children by Detjen, Anne K, McKenna, Lindsay, Graham, Stephen M, Marais, Ben J, Amanullah, Farhana

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Short-Term Reproducibility of a Commercial Interferon Gamma Release Assay by Detjen, A K, Loebenberg, L, Grewal, H M S, Stanley, K, Gutschmidt, A, Kruger, C, Du Plessis, N, Kidd, M, Beyers, N, Walzl, G, Hesseling, A C

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The oral multitarget tumour growth inhibitor, ZK 304709, inhibits growth of pancreatic neuroendocrine tumours in an orthotopic mouse model by Scholz, A, Wagner, K, Welzel, M, Remlinger, F, Wiedenmann, B, Siemeister, G, Rosewicz, S, Detjen, K M

“…Current systemic therapies for neuroendocrine tumours (NETs) do not provide sufficient control of tumour growth. However, efficient evaluation of novel drugs…”
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Molecular and pharmacodynamic characteristics of the novel multi-target tumor growth inhibitor ZK 304709 by Siemeister, G., Luecking, U., Wagner, C., Detjen, K., Mc Coy, C., Bosslet, Klaus

“…Loss of cell cycle control and tumor-induced neovascularization are major drivers of human tumor growth. The multi-target tumor growth inhibitor ZK 304709 is a…”
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The proline TP53 variant stimulates likely lymphangiogenesis in an orthotopic mouse model of pancreatic cancer by Otto, N, Schulz, P, Scholz, A, Hauff, P, Schlegelberger, B, Detjen, K M, Wiedenmann, B

“…Background: Pancreatic cancer is a deadly disease characterised by high incidence of TP53 mutations. Restoration of TP53 function is perceived as a highly…”
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Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children by Kay, Alexander W, González Fernández, Lucia, Takwoingi, Yemisi, Eisenhut, Michael, Detjen, Anne K, Steingart, Karen R, Mandalakas, Anna M

“…Every year, at least one million children become ill with tuberculosis and around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health…”
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Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis by Schulz, P, Scholz, A, Rexin, A, Hauff, P, Schirner, M, Wiedenmann, B, Detjen, K

“…Functional inactivation of the tumour suppressor protein p16 INK4a constitutes a key event in the multistep process of pancreatic ductal cell transformation…”
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Interferon-gamma release assays for the detection of Mycobacterium tuberculosis infection in children with cancer by STEFAN, D. C, DIPPENAAR, A, DETJEN, A. K, SCHAAF, H. S, MARAIS, B. J, KRIEL, B, LOEBENBERG, L, WALZL, G, HESSELING, A. C

“…SETTING: The paediatric oncology unit at Tygerberg Children's Hospital, South Africa.OBJECTIVES: To assess the use of the tuberculin skin test (TST) and two…”
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The Union and Médecins Sans Frontières approach to operational research [State of the art series. Operational research. Number 2 in the series] by HARRIES, A. D, RUSEN, I. D, ZACHARIAH, R, REID, T, DETJEN, A. K, BERGER, S. D, BISSELL, K, HINDERAKER, S. G, EDGINTON, M, FUSSELL, M, FUJIWARA, P. I

“…Operational research (OR) has become a hot topic at national meetings, international conferences and donor fora. The International Union Against Tuberculosis…”
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Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update by Graham, Stephen M., Cuevas, Luis E., Jean-Philippe, Patrick, Browning, Renee, Casenghi, Martina, Detjen, Anne K., Gnanashanmugam, Devasena, Hesseling, Anneke C., Kampmann, Beate, Mandalakas, Anna, Marais, Ben J., Schito, Marco, Spiegel, Hans M. L., Starke, Jeffrey R., Worrell, Carol, Zar, Heather J.

“…Consensus case definitions for childhood tuberculosis have been proposed by an international expert panel, aiming to standardize the reporting of cases in…”
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PO-329 Genomic aberration in pancreatic neuroendocrine tumours (PNET) by Simon, T, Mamlouk, S, Khouja, S, Andrea, M, Dido, L, Detjen, K, Pavel, M, Rossner, F, Haybäck, J, Sers, C

“…IntroductionRare tumours are poorly investigated and therefore heavily limited in possible therapeutic approaches, and subsequently therapeutic success. One…”
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Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children by Kay, Alexander W, Ness, Tara, Verkuijl, Sabine E, Viney, Kerri, Brands, Annemieke, Masini, Tiziana, González Fernández, Lucia, Eisenhut, Michael, Detjen, Anne K, Mandalakas, Anna M, Steingart, Karen R, Takwoingi, Yemisi

“…Every year, an estimated one million children and young adolescents become ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra…”
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EDITORIAL COMMENTARY: Improving Children's Access to New Tuberculosis Diagnostic Tools Starts With the Collection of Appropriate Specimens by Detjen, Anne K., Walters, Elisabetta

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