Search Results - "DESSY, Chantal"

Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects by Dierge, Emeline, Debock, Elena, Guilbaud, Céline, Corbet, Cyril, Mignolet, Eric, Mignard, Louise, Bastien, Estelle, Dessy, Chantal, Larondelle, Yvan, Feron, Olivier

“…Tumor acidosis promotes disease progression through a stimulation of fatty acid (FA) metabolism in cancer cells. Instead of blocking the use of FAs by acidic…”
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TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells by Corbet, Cyril, Bastien, Estelle, Santiago de Jesus, Joao Pedro, Dierge, Emeline, Martherus, Ruben, Vander Linden, Catherine, Doix, Bastien, Degavre, Charline, Guilbaud, Céline, Petit, Laurenne, Michiels, Carine, Dessy, Chantal, Larondelle, Yvan, Feron, Olivier

“…Acidosis, a common characteristic of the tumor microenvironment, is associated with alterations in metabolic preferences of cancer cells and progression of the…”
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Hyaluronidase 1 Deficiency Preserves Endothelial Function and Glycocalyx Integrity in Early Streptozotocin-Induced Diabetes by Dogné, Sophie, Rath, Géraldine, Jouret, François, Caron, Nathalie, Dessy, Chantal, Flamion, Bruno

“…Hyaluronic acid (HA) is a major component of the glycocalyx involved in the vascular wall and endothelial glomerular permeability barrier. Endocytosed…”
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Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors by BOIDOT, Romain, VEGRAN, Frédérique, MEULLE, Aline, LE BRETON, Aude, DESSY, Chantal, SONVEAUX, Pierre, LIZARD-NACOL, Sarab, FERON, Olivier

“…The monocarboxylate transporter (MCT) family member MCT1 can transport lactate into and out of tumor cells. Whereas most oxidative cancer cells import lactate…”
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Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering by Duisit, Jérôme, Amiel, Hadrien, Wüthrich, Tsering, Taddeo, Adriano, Dedriche, Adeline, Destoop, Vincent, Pardoen, Thomas, Bouzin, Caroline, Joris, Virginie, Magee, Derek, Vögelin, Esther, Harriman, David, Dessy, Chantal, Orlando, Giuseppe, Behets, Catherine, Rieben, Robert, Gianello, Pierre, Lengelé, Benoît

“…[Display omitted] Introduction: Human ear reconstruction is recognized as the emblematic enterprise in tissue engineering. Up to now, it has failed to reach…”
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Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase by Belge, Catharina, Hammond, Joanna, Dubois-Deruy, Emilie, Manoury, Boris, Hamelet, Julien, Beauloye, Christophe, Markl, Andreas, Pouleur, Anne-Catherine, Bertrand, Luc, Esfahani, Hrag, Jnaoui, Karima, Götz, Konrad R, Nikolaev, Viacheslav O, Vanderper, Annelies, Herijgers, Paul, Lobysheva, Irina, Iaccarino, Guido, Hilfiker-Kleiner, Denise, Tavernier, Geneviève, Langin, Dominique, Dessy, Chantal, Balligand, Jean-Luc

“…BACKGROUND—β1-2-adrenergic receptors (AR) are key regulators of cardiac contractility and remodeling in response to catecholamines. β3-AR expression is…”
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AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes by Balteau, Magali, Van Steenbergen, Anne, Timmermans, Aurélie D, Dessy, Chantal, Behets-Wydemans, Gaetane, Tajeddine, Nicolas, Castanares-Zapatero, Diego, Gilon, Patrick, Vanoverschelde, Jean-Louis, Horman, Sandrine, Hue, Louis, Bertrand, Luc, Beauloye, Christophe

“…Exposure of cardiomyocytes to high glucose concentrations (HG) stimulates reactive oxygen species (ROS) production by NADPH oxidase (NOX2). NOX2 activation is…”
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Chitin–glucan and pomegranate polyphenols improve endothelial dysfunction by Neyrinck, Audrey M., Catry, Emilie, Taminiau, Bernard, Cani, Patrice D., Bindels, Laure B., Daube, Georges, Dessy, Chantal, Delzenne, Nathalie M.

“…The vascular dysfunction is the primary event in the occurrence of cardio-vascular risk, and no treatment exists until now. We tested for the first time the…”
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Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice by van den Brule, Sybille, Rappe, Margaux, Ambroise, Jérôme, Bouzin, Caroline, Dessy, Chantal, Paquot, Adrien, Muccioli, Giulio G, Lison, Dominique

“…Ambient air pollution by particulate matters, including diesel exhaust particles (DEP), is a major cause of cardiovascular and metabolic mortality worldwide…”
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miR-199a Downregulation as a Driver of the NOX4/HIF-1α/VEGF-A Pathway in Thyroid and Orbital Adipose Tissues from Graves' Patients by Craps, Julie, Joris, Virginie, Baldeschi, Lelio, Daumerie, Chantal, Camboni, Alessandra, Buemi, Antoine, Lengelé, Benoit, Behets, Catherine, Boschi, Antonella, Mourad, Michel, Many, Marie-Christine, Dessy, Chantal

“…Graves' disease (GD) is an autoimmune thyroiditis often associated with Graves' orbitopathy (GO). GD thyroid and GO orbital fat share high oxidative stress…”
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Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia : Implications for anticancer therapies by MARTINIVE, Philippe, DEFRESNE, Florence, BOUZIN, Caroline, SALIEZ, Julie, LAIR, Florence, GREGOIRE, Vincent, MICHIELS, Carine, DESSY, Chantal, FERON, Olivier

“…Hypoxia is a common feature in tumors associated with an increased resistance of tumor cells to therapies. In addition to O(2) diffusion-limited hypoxia,…”
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Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation by Horckmans, Michael, Esfahani, Hrag, Beauloye, Christophe, Clouet, Sophie, di Pietrantonio, Larissa, Robaye, Bernard, Balligand, Jean-Luc, Boeynaems, Jean-Marie, Dessy, Chantal, Communi, Didier

“…Nucleotides are released in the heart under pathological conditions, but little is known about their contribution to cardiac inflammation. The present study…”
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Moderate Caveolin-1 Downregulation Prevents NADPH Oxidase–Dependent Endothelial Nitric Oxide Synthase Uncoupling by Angiotensin II in Endothelial Cells by Lobysheva, Irina, Rath, Géraldine, Sekkali, Belaïd, Bouzin, Caroline, Feron, Olivier, Gallez, Bernard, Dessy, Chantal, Balligand, Jean-Luc

“…OBJECTIVE—We analyzed the role of caveolin-1 (Cav-1) in the cross-talk between NADPH oxidase and endothelial nitric oxide synthase (eNOS) signaling in…”
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Targeting M2 Macrophages with a Novel NADPH Oxidase Inhibitor by Dilly, Sébastien, Romero, Miguel, Solier, Stéphanie, Feron, Olivier, Dessy, Chantal, Slama Schwok, Anny

“…ROS in cancer cells play a key role in pathways regulating cell death, stemness maintenance, and metabolic reprogramming, all of which have been implicated in…”
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Nebivolol Exerts Beneficial Effects on Endothelial Function, Early Endothelial Progenitor Cells, Myocardial Neovascularization, and Left Ventricular Dysfunction Early After Myocardial Infarction Beyond Conventional β1 -Blockade by Sorrentino, Sajoscha A., MD, Doerries, Carola, MD, Manes, Costantina, MD, Speer, Thimoteus, MD, Dessy, Chantal, PhD, Lobysheva, Irina, PhD, Mohmand, Wazma, MD, Akbar, Razma, MD, Bahlmann, Ferdinand, MD, PhD, Besler, Christian, MD, Schaefer, Arnd, MD, Hilfiker-Kleiner, Denise, PhD, Lüscher, Thomas F., MD, Balligand, Jean-Luc, MD, PhD, Drexler, Helmut, MD, Landmesser, Ulf, MD

“…Objectives The aim of this study was to investigate whether nebivolol has added effects on left ventricular (LV) dysfunction and remodeling early after…”
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Vascular Hypoxic Preconditioning Relies on TRPV4-Dependent Calcium Influx and Proper Intercellular Gap Junctions Communication by Rath, Géraldine, Saliez, Julie, Behets, Gaëtane, Romero-Perez, Miguel, Leon-Gomez, Elvira, Bouzin, Caroline, Vriens, Joris, Nilius, Bernd, Feron, Olivier, Dessy, Chantal

“…OBJECTIVE—We investigated the impact of hypoxia-reoxygenation on endothelial relaxation and aimed to clarify the role of transient receptor potential cation…”
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Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis by Decrem, Yves, Rath, Géraldine, Blasioli, Virginie, Cauchie, Philippe, Robert, Séverine, Beaufays, Jérôme, Frère, Jean-Marie, Feron, Olivier, Dogné, Jean-Michel, Dessy, Chantal, Vanhamme, Luc, Godfroid, Edmond

“…Blood coagulation starts immediately after damage to the vascular endothelium. This system is essential for minimizing blood loss from an injured blood vessel…”
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Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis by Romero, Miguel, Leon-Gomez, Elvira, Lobysheva, Irina, Rath, Géraldine, Dogné, Jean-Michel, Feron, Olivier, Dessy, Chantal

“…Endothelial dysfunction is considered to be an early event in atherosclerosis and plays a pivotal role in the development, progression and clinical…”
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Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects by Madlala, Hlengiwe P, Metzinger, Thomas, van Heerden, Fanie R, Musabayane, Cephas T, Mubagwa, Kanigula, Dessy, Chantal

“…Plant-derived oleanolic acid (OA) and its related synthetic derivatives (Br-OA and Me-OA) possess antihypertensive effects in experimental animals. The present…”
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The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the ‘endothelium-derived hyperpolarizing factor’ by Dessy, Chantal, Feron, Olivier, Balligand, Jean-Luc

“…The endothelium plays a crucial role in the regulation of cardiovascular homeostasis through the release of vasoactive autacoids such as nitric oxide,…”
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