Search Results - "DESNOS, Michel"

Transplantation of Human Embryonic Stem Cell–Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction by Menasché, Philippe, Vanneaux, Valérie, Hagège, Albert, Bel, Alain, Cholley, Bernard, Parouchev, Alexandre, Cacciapuoti, Isabelle, Al-Daccak, Reem, Benhamouda, Nadine, Blons, Hélène, Agbulut, Onnik, Tosca, Lucie, Trouvin, Jean-Hugues, Fabreguettes, Jean-Roch, Bellamy, Valérie, Charron, Dominique, Tartour, Eric, Tachdjian, Gérard, Desnos, Michel, Larghero, Jérôme

“…In addition to scalability, human embryonic stem cells (hESCs) have the unique advantage of allowing their directed differentiation toward lineage-specific…”
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Sports-Related Sudden Death in the General Population by MARIJON, Eloi, TAFFLET, Muriel, LE HEUZEY, Jean-Yves, EMPANA, Jean-Philippe, JOUVEN, Xavier, CELERMAJER, David S, DUMAS, Florence, PERIER, Marie-Cécile, MUSTAFIC, Hazrije, TOUSSAINT, Jean-François, DESNOS, Michel, RIEU, Michel, BENAMEUR, Nordine

“…Although such data are available for young competitive athletes, the prevalence, characteristics, and outcome of sports-related sudden death have not been…”
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Towards a clinical use of human embryonic stem cell-derived cardiac progenitors: a translational experience by Menasché, Philippe, Vanneaux, Valérie, Fabreguettes, Jean-Roch, Bel, Alain, Tosca, Lucie, Garcia, Sylvie, Bellamy, Valérie, Farouz, Yohan, Pouly, Julia, Damour, Odile, Périer, Marie-Cécile, Desnos, Michel, Hagège, Albert, Agbulut, Onnik, Bruneval, Patrick, Tachdjian, Gérard, Trouvin, Jean-Hugues, Larghero, Jérôme

“…There is now compelling evidence that cells committed to a cardiac lineage are most effective for improving the function of infarcted hearts. This has been…”
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Heart-Rate Profile during Exercise as a Predictor of Sudden Death by Jouven, Xavier, Empana, Jean-Philippe, Schwartz, Peter J, Desnos, Michel, Courbon, Dominique, Ducimetière, Pierre

“…In asymptomatic French men, the heart-rate profile during exercise testing was found to be predictive of the subsequent risk of sudden death. Specifically, a…”
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Relation of Heart Rate at Rest and Long-Term (>20 Years) Death Rate in Initially Healthy Middle-Aged Men by Jouven, Xavier, MD, PhD, Empana, Jean Philippe, MD, PhD, Escolano, Sylvie, PhD, Buyck, Jean François, MD, Tafflet, Muriel, PhD, Desnos, Michel, MD, Ducimetière, Pierre, PhD

“…The prognostic implications of heart rate (HR) change over years have never been assessed. It was hypothesized that an increase in HR in apparently healthy…”
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A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates by Blin, Guillaume, Nury, David, Stefanovic, Sonia, Neri, Tui, Guillevic, Oriane, Brinon, Benjamin, Bellamy, Valérie, Rücker-Martin, Catherine, Barbry, Pascal, Bel, Alain, Bruneval, Patrick, Cowan, Chad, Pouly, Julia, Mitalipov, Shoukhrat, Gouadon, Elodie, Binder, Patrice, Hagège, Albert, Desnos, Michel, Renaud, Jean-François, Menasché, Philippe, Pucéat, Michel

“…Cell therapy holds promise for tissue regeneration, including in individuals with advanced heart failure. However, treatment of heart disease with bone marrow…”
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Galectin-3: A new biomarker for the diagnosis, analysis and prognosis of acute and chronic heart failure by Hrynchyshyn, Nataliya, Jourdain, Patrick, Desnos, Michel, Diebold, Benoit, Funck, François

“…Summary Heart failure constitutes an important medical, social and economic problem. The prevalence of heart failure is estimated as 2–3% of the adult…”
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First clinical use of a bioprosthetic total artificial heart: report of two cases by Carpentier, Alain, Prof, Latrémouille, Christian, Prof, Cholley, Bernard, Prof, Smadja, David M, Prof, Roussel, Jean-Christian, Prof, Boissier, Elodie, MD, Trochu, Jean-Noël, Prof, Gueffet, Jean-Pierre, Prof, Treillot, Michèle, Prof, Bizouarn, Philippe, MD, Méléard, Denis, MD, Boughenou, Marie-Fazia, MD, Ponzio, Olivier, MD, Grimmé, Marc, MEng, Capel, Antoine, MSc, Jansen, Piet, MD, Hagège, Albert, Prof, Desnos, Michel, Prof, Fabiani, Jean-Noël, Prof, Duveau, Daniel, Prof

“…Summary Background The development of artificial hearts in patients with end-stage heart disease have been confronted with the major issues of thromboembolism…”
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Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study by Ménard, Claudine, Hagège, Albert A, Agbulut, Onnik, Barro, Marietta, Morichetti, Miguel Cortes, Brasselet, Camille, Bel, Alain, Messas, Emmanuel, Bissery, Alvine, Bruneval, Patrick, Desnos, Michel, Pucéat, Michel, Menasché, Philippe

“…Heart failure develops after myocardial infarction and is a major cause of morbidity and mortality. The ability to direct differentiation of embryonic stem…”
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Differentiation In Vivo of Cardiac Committed Human Embryonic Stem Cells in Postmyocardial Infarcted Rats by Tomescot, André, Leschik, Julia, Bellamy, Valérie, Dubois, Gilbert, Messas, Emmanuel, Bruneval, Patrick, Desnos, Michel, Hagège, Albert A., Amit, Michal, Itskovitz, Joseph, Menasché, Philippe, Pucéat, Michel

“…Human embryonic stem (HES) cells can give rise to cardiomyocytes in vitro. However, whether undifferentiated HES cells also feature a myocardial regenerative…”
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Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium by Perez-Ilzarbe, Maitane, Agbulut, Onnik, Pelacho, Beatriz, Ciorba, Cristina, Jose-Eneriz, Edurne San, Desnos, Michel, Hagège, Albert A., Aranda, Pablo, Andreu, Enrique J., Menasché, Philippe, Prósper, Felipe

“…Abstract Background: The discrepancy between the functional improvements yielded experimentally by skeletal myoblasts (SM) transplanted in infarcted myocardium…”
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Awareness of Individual Cardiovascular Risk Factors and Self-Perception of Cardiovascular Risk in Women by Monsuez, Jean-Jacques, MD, PhD, Pham, Tai, MD, Karam, Nicole, MD, Amar, Laurence, MD, Chicheportiche-Ayache, Corinne, MD, Menasché, Philippe, MD, PhD, Desnos, Michel, MD, PhD, Weill, Isabelle

“…Abstract Background Cardiovascular risk factors (CVRF) self-perception by women may be inaccurate. Methods A questionnaire was filled on an anonymous basis…”
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Survival from sports-related sudden cardiac arrest: In sports facilities versus outside of sports facilities by Marijon, Eloi, MD, PhD, Bougouin, Wulfran, MD, Karam, Nicole, MD, Beganton, Frankie, MS, Lamhaut, Lionel, MD, Perier, Marie-Cécile, MPH, Benameur, Nordine, MD, Tafflet, Muriel, PhD, Beal, Guillaume, MS, Hagege, Albert, MD, Le Heuzey, Jean-Yves, MD, Desnos, Michel, MD, Spaulding, Christian, MD, Carré, Francois, MD, PhD, Dumas, Florence, MD, PhD, Celermajer, David S., PhD, FRACP, Cariou, Alain, MD, Jouven, Xavier, MD, PhD

“…Background We sought to evaluate frequency, characteristics, and outcomes of sudden cardiac arrest (SCA) during sports activities according to the location of…”
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Heart rate and risk of cancer death in healthy men by Jouven, Xavier, Escolano, Sylvie, Celermajer, David, Empana, Jean-Philippe, Bingham, Annie, Hermine, Olivier, Desnos, Michel, Perier, Marie-Cécile, Marijon, Eloi, Ducimetière, Pierre

“…Data from several previous studies examining heart-rate and cardiovascular risk have hinted at a possible relationship between heart-rate and non-cardiac…”
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Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population by JOUVEN, Xavier, CHARLES, Marie-Aline, DESNOS, Michel, DUCIMETIERE, Pierre

“…In ischemic conditions, concentration of circulating nonesterified fatty acids (NEFA) is increased and has a proarrhythmic effect that is responsible for…”
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Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report: Figure 1 by Menasché, Philippe, Vanneaux, Valérie, Hagège, Albert, Bel, Alain, Cholley, Bernard, Cacciapuoti, Isabelle, Parouchev, Alexandre, Benhamouda, Nadine, Tachdjian, Gérard, Tosca, Lucie, Trouvin, Jean-Hugues, Fabreguettes, Jean-Roch, Bellamy, Valérie, Guillemain, Romain, Suberbielle Boissel, Caroline, Tartour, Eric, Desnos, Michel, Larghero, Jérôme

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Immune response to human embryonic stem cell‐derived cardiac progenitors and adipose‐derived stromal cells by Calderon, Damelys, Planat‐Benard, Valérie, Bellamy, Valérie, Vanneaux, Valérie, Kuhn, Chantal, Peyrard, Severine, Larghero, Jéröome, Desnos, Michel, Casteilla, Louis, Pucéat, Michel, Menasché, Philippe, Chatenoud, Lucienne

“…Transplantation of allogeneic human embryonic stem cell‐derived cardiac progenitors triggers an immune response. We assessed whether this response could be…”
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Efficacy of chordal cutting to relieve chronic persistent ischemic mitral regurgitation by MESSAS, Emmanuel, POUZET, Bruno, TOUCHOT, Bernard, GUERRERO, J. Luis, VLAHAKES, Gus J, DESNOS, Michel, MENASCHE, Philippe, HAGEGE, Albert, LEVINE, Robert A

“…Mitral regurgitation (MR) conveys adverse prognosis in ischemic heart disease. Leaflet closure is restricted by tethering to displaced papillary muscles, and…”
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Can Mesenchymal Stem Cells Induce Tolerance to Cotransplanted Human Embryonic Stem Cells? by Puymirat, Etienne, Geha, Raghed, Tomescot, André, Bellamy, Valérie, Larghero, Jérôme, Trinquart, Ludovic, Bruneval, Patrick, Desnos, Michel, Hagège, Albert, Pucéat, Michel, Menasché, Philippe

“…Mesenchymal stem cells (MSCs) are reported to be immune privileged. We assessed whether their transplantation (Tx) could create a suppressive microenvironment…”
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Relief of mitral leaflet tethering following chronic myocardial infarction by chordal cutting diminishes left ventricular remodeling by Messas, Emmanuel, Bel, Alain, Szymanski, Catherine, Cohen, Iris, Touchot, Bernard, Handschumacher, Mark D, Desnos, Michel, Carpentier, Alain, Menasché, Philippe, Hagège, Albert A, Levine, Robert A

“…one of the key targets in treating mitral regurgitation (MR) is reducing the otherwise progressive left ventricular (LV) remodeling that exacerbates MR and…”
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