Search Results - "DESMYTER, Jan"

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds by Pauwels, R, Balzarini, J, Baba, M, Snoeck, R, Schols, D, Herdewijn, P, Desmyter, J, De Clercq, E

“…A rapid, sensitive and automated assay procedure was developed for the in vitro evaluation of anti-HIV agents. An HTLV-I transformed T4-cell line, MT-4, which…”
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Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir) by Esté, J A, Cabrera, C, Schols, D, Cherepanov, P, Gutierrez, A, Witvrouw, M, Pannecouque, C, Debyser, Z, Rando, R F, Clotet, B, Desmyter, J, De Clercq, E

“…The human immunodeficiency virus (HIV) inhibitor AR177 (T30177, Zintevir) has been identified as a potent inhibitor of HIV integrase in vitro. The compound is…”
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Different Population Dynamics of Human T Cell Lymphotropic Virus Type II in Intravenous Drug Users Compared with Endemically Infected Tribes by Salemi, Marco, Lewis, Martha, Egan, John Fergal, Hall, William W., Desmyter, Jan, Vandamme, Anne-Mieke

“…The phylogeny of human T cell lymphotropic virus type II (HTLV-II) was investigated by using strains isolated from Amerindian and Pygmy tribes, in which the…”
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Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV by WITVROUW, M, PANNECOUQUE, C, VAN LAETHEM, K, DESMYTER, J, DE CLERCQ, E, VANDAMME, A.-M

“…After the initial discovery of 1-(2-hydroxyethoxymethyl)-6-(phenylthio)thymine (HEPT) and tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and thione…”
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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives by Pauwels, Rudi, Andries, Koen, Desmyter, Jan, Schols, Dominique, Kukla, Michael J, Breslin, Henry J, Raeymaeckers, Alfons, Gelder, Jozef Van, Woestenborghs, Robert, Heykants, Jozef, Schellekens, Karel, Janssen, Marcel A. C, Clercq, Erik De, Janssen, Paul A. J

“…In the search for compounds active against human immunodeficiency virus (HIV), we have found that members of a novel series of…”
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African Origin of Human T-Lymphotropic Virus Type 2 (HTLV-2) Supported by a Potential New HTLV-2d Subtype in Congolese Bambuti Efe Pygmies by Vandamme, A M, Salemi, M, Van Brussel, M, Liu, H F, Van Laethem, K, Van Ranst, M, Michels, L, Desmyter, J, Goubau, P

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Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein by Este, J A, Schols, D, De Vreese, K, Van Laethem, K, Vandamme, A M, Desmyter, J, De Clercq, E

“…Polyanionic compounds are known to inhibit the binding of human immunodeficiency virus (HIV) to CD4+ cells and the subsequent fusion step between the virus and…”
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Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro by Baba, M, Pauwels, R, Herdewijn, P, De Clercq, E, Desmyter, J, Vandeputte, M

“…2',3'-Dideoxythymidine (ddThd) and its 2',3'-unsaturated derivative 2',3'-dideoxythymidinene (ddeThd) are potent and selective inhibitors of human…”
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The Jezierski papers: live polio vaccine development in colobus monkey cells but not chimpanzee cells in the Belgian Congo, 1952–1958 by Desmyter, Jan, Teuwen, Dirk E.

“…A reading of ten relevant papers by Alexandre Jezierski provides evidence for the only attempt in Central Africa to develop a live oral polio vaccine (OPV)…”
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Postscript relating to new allegations made by Edward Hooper at The Royal Society Discussion Meeting on 11 September 2000 by Plotkin, Stanley A., Teuwen, Dirk E., Prinzie, Abel, Desmyter, Jan

“… These were proposed as conclusive evidence for the hypothesis that simian immunodeficiency virus–contaminated CHAT polio vaccine caused the HIV–1 group M…”
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Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach by Santos, Terezinha de Jesus Teixeira, Costa, Carlos Maurício de Castro, Goubau, Patrick, Vandamme, Anne-Mieke, Desmyter, Jan, Van Dooren, Sonia, Mota, Rosa M. S., Costa, Francine Bovy de Castro, Oliveira, Ana C. S., Gomes, Vânia Barreto A.F., Carneiro-Proietti, Anna B., Bruin, Veralice Meireles Sales de, Sousa, Francisca C. F. de, Oriá, Reinaldo Barreto

“…How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam…”
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The simian origins of the pathogenic human T-cell lymphotropic virus type I by Vandamme, Anne-Mieke, Salemi, Marco, Desmyter, Jan

“…At least four, and possibly six, molecular subtypes of human T-cell lymphotropic virus type I (HTLV-I) exist: one is confined to Melanesia/Australia, one is…”
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Defectiveness of Interferon Production and of Rubella Virus Interference in a Line of African Green Monkey Kidney Cells (Vero) by Desmyter, J, Melnick, J L, Rawls, W E

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Prevalence and Characteristics of Multinucleoside-Resistant Human Immunodeficiency Virus Type 1 among European Patients Receiving Combinations of Nucleoside Analogues by VAN VAERENBERGH, K, VAN LAETHEM, K, PERRIN, L, PIRILLO, M. F, RUIZ, L, SCHMIT, J.-C, SCHNEIDER, F, SCHOOLMEESTER, A, SCHUURMAN, R, STELLBRINK, H. J, STUYVER, L, VAN LUNZEN, J, ALBERT, J, VAN REMOORTEL, B, VAN WIJNGAERDEN, E, VELLA, S, WITVROUW, M, YERLY, S, DE CLERCQ, E, DESMYTER, J, VANDAMME, A.-M, BOUCHER, C. A. B, CLOTET, B, FLORIDIA, M, GERSTOFT, J, HEJDEMAN, B, NIELSEN, C, PANNECOUQUE, C

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Two New Human T-Lymphotropic Virus Type I Phylogenetic Subtypes in Seroindeterminates, a Mbuti Pygmy and a Gabonese, Have Closest Relatives among African STLV-I Strains by Salemi, Marco, Van Dooren, Sonia, Audenaert, Elke, Delaporte, Eric, Goubau, Patrick, Desmyter, Jan, Vandamme, Anne-Mieke

“…Six new HTLV-I strains from seroindeterminate individuals were analyzed: four from Gabon, one from a Mbuti Efe pygmy in Congo (formerly Zaire), and one from a…”
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HTLV-II among pygmies by Goubau, Patrick, Desmyter, Jan, Ghesquiere, Joseph, Kasereka, Busaka

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Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries by SCHMIT, J.-C, VAN LAETHEM, K, LISSEN, E, WITVROUW, M, DESMYTER, J, DE CLERCQ, E, VANDAMME, A.-M, RUIZ, L, HERMANS, P, SPRECHER, S, SÖNNERBORG, A, LEAL, M, HARRER, T, CLOTET, B, ARENDT, V

“…To study the prevalence of multiple dideoxynucleoside (ddN)-resistant (MddNR) HIV-1 in European patients under treatment with multiple ddN analogues, and to…”
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Multiple Drug Resistance to Nucleoside Analogues and Nonnucleoside Reverse Transcriptase Inhibitors in an Efficiently Replicating Human Immunodeficiency Virus Type 1 Patient Strain by Schmit, Jean-Claude, Cogniaux, Jacqueline, Hermans, Philippe, Van Vaeck, Christophe, Sprecher, Susi, Van Remoortel, Barbara, Witvrouw, Myriam, Balzarini, Jan, Desmyter, Jan, De Clercq, Erik, Vandamme, Anne-Mieke

“…A human immunodeficiency virus type 1 (HIV-1)–seropositive patient was treated sequentially with the dideoxynucleoside (ddN) analogues zidovudine, didanosine,…”
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Dextran sulfate and other polyanionic anti-HIV compounds specifically interact with the viral gp120 glycoprotein expressed by T-cells persistently infected with HIV-1 by Schols, D, Pauwels, R, Desmyter, J, De Clercq, E

“…Eighty to 100% of persistently HIV-1-infected HUT-78 cells express the viral glycoprotein gp120 as demonstrated with anti-gp 120 monoclonal antibody (mAb) and…”
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Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538) by Schmit, J C, Ruiz, L, Clotet, B, Raventos, A, Tor, J, Leonard, J, Desmyter, J, De Clercq, E, Vandamme, A M

“…To define genotypic and phenotypic resistance patterns following prolonged therapy with the protease inhibitor ritonavir (ABT-538). Seven HIV-1-infected…”
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