Search Results - "DESMOTS, Fabienne"

Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P-Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases by Dubois, Sydney, Viailly, Pierre-Julien, Bohers, Elodie, Bertrand, Philippe, Ruminy, Philippe, Marchand, Vinciane, Maingonnat, Catherine, Mareschal, Sylvain, Picquenot, Jean-Michel, Penther, Dominique, Jais, Jean-Philippe, Tesson, Bruno, Peyrouze, Pauline, Figeac, Martin, Desmots, Fabienne, Fest, Thierry, Haioun, Corinne, Lamy, Thierry, Copie-Bergman, Christiane, Fabiani, Bettina, Delarue, Richard, Peyrade, Frédéric, André, Marc, Ketterer, Nicolas, Leroy, Karen, Salles, Gilles, Molina, Thierry J, Tilly, Hervé, Jardin, Fabrice

“…mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of activated B-cell like (ABC) diffuse large B-cell lymphoma…”
Get full text

Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study by Dubois, Sydney, Viailly, Pierre-Julien, Mareschal, Sylvain, Bohers, Elodie, Bertrand, Philippe, Ruminy, Philippe, Maingonnat, Catherine, Jais, Jean-Philippe, Peyrouze, Pauline, Figeac, Martin, Molina, Thierry J, Desmots, Fabienne, Fest, Thierry, Haioun, Corinne, Lamy, Thierry, Copie-Bergman, Christiane, Brière, Josette, Petrella, Tony, Canioni, Danielle, Fabiani, Bettina, Coiffier, Bertrand, Delarue, Richard, Peyrade, Frédéric, Bosly, André, André, Marc, Ketterer, Nicolas, Salles, Gilles, Tilly, Hervé, Leroy, Karen, Jardin, Fabrice

“…Next-generation sequencing (NGS) has detailed the genomic characterization of diffuse large B-cell lymphoma (DLBCL) by identifying recurrent somatic mutations…”
Get full text

BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy by Sebti, Salwa, Prébois, Christine, Pérez-Gracia, Esther, Bauvy, Chantal, Desmots, Fabienne, Pirot, Nelly, Gongora, Céline, Bach, Anne-Sophie, Hubberstey, Andrew V., Palissot, Valérie, Berchem, Guy, Codogno, Patrice, Linares, Laetitia K., Liaudet-Coopman, Emmanuelle, Pattingre, Sophie

“…Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B—associated transcript 3 (BAT3) is essential for basal…”
Get full text

Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation by Santamaria, Kathleen, Desmots, Fabienne, Leonard, Simon, Caron, Gersende, Haas, Marion, Delaloy, Céline, Chatonnet, Fabrice, Rossille, Delphine, Pignarre, Amandine, Monvoisin, Céline, Seffals, Marine, Lamaison, Claire, Cogné, Michel, Tarte, Karin, Fest, Thierry

“…B cell affinity maturation occurs in the germinal center (GC). Light-zone (LZ) GC B cells (B -cells) interact with follicular dendritic cells (FDCs) and…”
Get full text

Somatic mutations of cell-free circulating DNA detected by next-generation sequencing reflect the genetic changes in both germinal center B-cell-like and activated B-cell-like diffuse large B-cell lymphomas at the time of diagnosis by Bohers, Elodie, Viailly, Pierre Julien, Dubois, Sydney, Bertrand, Philippe, Maingonnat, Catherine, Mareschal, Sylvain, Ruminy, Philippe, Picquenot, Jean-Michel, Bastard, Christian, Desmots, Fabienne, Fest, Thierry, Leroy, Karen, Tilly, Hervé, Jardin, Fabrice

Get full text

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells by Pastoret, Cédric, Desmots, Fabienne, Drillet, Gaëlle, Le Gallou, Simon, Boulland, Marie-Laure, Thannberger, Alexia, Doncker, Anne-Violaine, Salaun, Véronique, Damaj, Gandhi Laurent, Veyrat-Masson, Richard, Tournilhac, Olivier, Moignet, Aline, Pangault, Céline, Roussel, Mikaël, Fest, Thierry, Lamy, Thierry

“…Distinguishing chronic lymphoproliferative disorders of NK cells (CLPD-NK) from reactive NK-cell expansion is challenging. We assessed the value of killer…”
Get full text

Scythe Regulates Apoptosis-inducing Factor Stability during Endoplasmic Reticulum Stress-induced Apoptosis by Desmots, Fabienne, Russell, Helen R., Michel, Denis, McKinnon, Peter J.

“…Scythe (BAT3; HLA-Bassociated transcript 3, Bag 6) is a protein that has been implicated in apoptosis because it can modulate the Drosophila melanogaster…”
Get full text

The Negative Influence of Baseline Cell-free DNA on Long-term Survival in DLBCL Depends on Frontline Treatment Intensity by Desmots, Fabienne, Rossille, Delphine, Roussel, Mikael, Pangault, Céline, Louarn, Laetitia, De Saint Jore, Mylène, Le Gouill, Steven, Bouabdallah, Krimo, Delwail, Vincent, Gressin, Remy, Cornillon, Jérôme, Damaj, Gandhi, Maisonneuve, Hervé, Damotte, Diane, Kraeber-Bodere, Françoise, Lamy, Thierry, Parrens, Marie-Cécile, Milpied, Noël, Fest, Thierry

“…This study aims to investigate the relationship between the intensity of the initial treatment given to patients with de novo diffuse large B-cell lymphoma…”
Get full text

The Reaper-Binding Protein Scythe Modulates Apoptosis and Proliferation during Mammalian Development by Desmots, Fabienne, Russell, Helen R., Lee, Youngsoo, Boyd, Kelli, McKinnon, Peter J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Plasmablasts derive from CD23– activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction by Pignarre, Amandine, Chatonnet, Fabrice, Caron, Gersende, Haas, Marion, Desmots, Fabienne, Fest, Thierry

“…The terminal differentiation of B cells into antibody-secreting cells (ASCs) is a critical component of adaptive immune responses. However, it is a very…”
Get full text

Immunohistological Analysis of Glutathione Transferase A4 Distribution in Several Human Tissues Using a Specific Polyclonal Antibody by Desmots, Fabienne, Rissel, Mary, Loyer, Pascal, Turlin, Bruno, Guillouzo, Andre

“…We examined the cellular distribution of glutathione transferase A4 (GSTA4) in various human tissues by indirect immunoperoxidase using a specific polyclonal…”
Get full text

Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices by Finot, Francis, Masson, Régis, Desmots, Fabienne, Ribault, Catherine, Bichet, Nicole, Vericat, Joan A., Lafouge, Patricia, Guguen-Guillouzo, Christiane, Loyer, Pascal

“…The culture liver slices are mainly used to investigate drug metabolism and xenobiotic-mediated liver injuries while apoptosis and proliferation remain…”
Get full text

Genomic organization, 5'-flanking region and chromosomal localization of the human glutathione transferase A4 gene by Desmots, F, Rauch, C, Henry, C, Guillouzo, A, Morel, F

“…We have isolated and characterized a human glutathione transferase A4 (hGSTA4) subunit gene from a yeast artificial chromosome containing several other…”
Get full text

Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma by Desmots, Fabienne, Roussel, Mikaël, Pangault, Céline, Llamas-Gutierrez, Francisco, Pastoret, Cédric, Guiheneuf, Eric, Le Priol, Jérôme, Camara-Clayette, Valérie, Caron, Gersende, Henry, Catherine, Belaud-Rotureau, Marc-Antoine, Godmer, Pascal, Lamy, Thierry, Jardin, Fabrice, Tarte, Karin, Ribrag, Vincent, Fest, Thierry

“…Follicular lymphoma arises from a germinal center B-cell proliferation supported by a bidirectional crosstalk with tumor microenvironment, in particular with…”
Get full text

Integrative Analysis of Cell Crosstalk within Follicular Lymphoma Cell Niche: Towards a Definition of the FL Supportive Synapse by Pangault, Céline, Amé-Thomas, Patricia, Rossille, Delphine, Dulong, Joëlle, Caron, Gersende, Nonn, Céline, Chatonnet, Fabrice, Desmots, Fabienne, Launay, Vincent, Lamy, Thierry, Fest, Thierry, Tarte, Karin

“…Follicular lymphoma (FL), the most frequent indolent non-Hodgkin’s B cell lymphoma, is considered as a prototypical centrocyte-derived lymphoma, dependent on a…”
Get full text

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization by Sebti, Salwa, Prébois, Christine, Pérez-Gracia, Esther, Bauvy, Chantal, Desmots, Fabienne, Pirot, Nelly, Gongora, Céline, Bach, Anne-Sophie, Hubberstey, Andrew V, Palissot, Valérie, Berchem, Guy, Codogno, Patrice, Linares, Laetitia K, Liaudet-Coopman, Emmanuelle, Pattingre, Sophie

“…We recently reported that BAG6/BAT3 (BCL2-associated athanogene 6) is essential for basal and starvation-induced autophagy in E18.5 bag6 −/− mouse embryos and…”
Get full text

Whole-genome expression analysis in primary human keratinocyte cell cultures exposed to 60 GHz radiation by Le Quément, Catherine, Nicolas Nicolaz, Christophe, Zhadobov, Maxim, Desmots, Fabienne, Sauleau, Ronan, Aubry, Marc, Michel, Denis, Le Dréan, Yves

“…The main purpose of this study is to investigate potential responses of skin cells to millimeter wave (MMW) radiation increasingly used in the wireless…”
Get full text

Abstract 4810: Exome sequencing of refractory diffuse large B-cell lymphomas highlights candidate genes for targeted resequencing by Mareschal, Sylvain, Viailly, Pierre-Julien, Bertrand, Philippe, Bohers, Elodie, Jais, Jean-Philippe, Figeac, Martin, Molina, Thierry J., Desmots, Fabienne, Fest, Thierry, Salles, Gilles, Haioun, Corinne, Tilly, Hervé, Leroy, Karen, Jardin, Fabrice

“…As the most common lymphoid malignancy, Diffuse Large B-Cell Lymphoma (DLBCL) has largely benefited from immunochemotherapy combinations developed in the past…”
Get full text

Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and Non-L265P Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases by Dubois, Sydney, Viailly, Pierre-Julien, Bohers, Elodie, Bertrand, Philippe, Ruminy, Philippe, Marchand, Vinciane, Maingonnat, Catherine, Mareschal, Sylvain, Picquenot, Jean-Michel, Penther, Dominique, Jais, Jean-Philippe, Tesson, Bruno, Peyrouze, Pauline, Figeac, Martin, Desmots, Fabienne, Fest, Thierry, Haioun, Corinne, Lamy, Thierry, Copie-Bergman, Christiane, Fabiani, Bettina, Delarue, Richard, Peyrade, Frédéric, Andre, Marc, Ketterer, Nicolas, Leroy, Karen, Salles, Gilles A., Molina, Thierry Jo, Tilly, Hervé, Jardin, Fabrice

“…Introduction: MYD88 mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of Activated B-Cell like (ABC) Diffuse Large…”
Get full text

Sequential interplay between BAG6 and HSP70 upon heat shock by Corduan, A., Lecomte, S., Martin, C., Michel, D., Desmots, F.

“… BAG6/Scythe/Bat3 is a cochaperone of the heat shock protein HSP70 and is involved in various developmental processes, cellular stress and viability. BAG6…”
Get full text