Search Results - "DESHPANDE, Prasad K."
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Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β‑Lactamase Inhibitors and β‑Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234
Published in Journal of medicinal chemistry (10-05-2018)“…Limited treatment options exist to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria possessing broad-spectrum β-lactamases. The…”
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Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence
Published in Drug design, development and therapy (01-12-2019)“…Levonadifloxacin and its prodrug alalevonadifloxacin are novel broad-spectrum anti-MRSA agents belonging to the benzoquinolizine subclass of quinolone,…”
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Identification of metabolites of novel Anti‐MRSA fluoroquinolone WCK 771 in mouse, rat, rabbit, dog, monkey and human urine using liquid chromatography tandem mass spectrometry
Published in Biomedical chromatography (01-07-2019)“…WCK 771 is an l‐arginine salt of levonadifloxacin (LND) being developed in intravenous dosage form and has recently completed a phase III trial in India. The…”
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A Chiral Benzoquinolizine-2-carboxylic Acid Arginine Salt Active against Vancomycin-Resistant Staphylococcus aureus
Published in Journal of medicinal chemistry (11-08-2005)“…There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive…”
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A Chiral Benzoquinolizine-2-carboxylic Acid Arginine Salt Active against Vancomycin-Resistant Staphylococcus a ureus
Published in Journal of medicinal chemistry (11-08-2005)“…There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive…”
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A new chiral oxazolidinone derived from diphenylalaninol. Aldol, alkylation, and diels-alder reactions
Published in Tetrahedron letters (04-12-1995)“…The chemistry of a new chiral oxazolidinone derived from D-diphenylalamnol is described. Aldol. alkylation. and Diels-Alder reactions using this auxiliary…”
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Synthesis of N-BOC-D-diphenylalanine from L-serine methyl ester hydrochloride
Published in Tetrahedron letters (04-12-1995)“…A convenient six step synthesis of N-BOC-D-diphenylalanine from L-serine methyl ester hydrochloride is described. The preparation of a novel chiral auxiliary,…”
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Synthesis of biologically active compounds of agricultural interest
Published in Pure and applied chemistry (01-01-1990)Get full text
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