Search Results - "DERVAN, P"

Molecular recognition of DNA by small molecules by Dervan, Peter B.

Get full text

Radiosensitization by DNA, Binding Pyrrole, Imidazole Polyamides by Kummer, N.T, Yang, F, Dervan, P, Nickols, N

Get full text

The Birmingham Irradiation Facility by Dervan, P., French, R., Hodgson, P., Marin-Reyes, H., Wilson, J.

“…At the end of 2012 the proton irradiation facility at the CERN PS [1] will shut down for two years. With this in mind, we have been developing a new ATLAS…”
Get full text

Upgrade to the Birmingham Irradiation Facility by Dervan, P., French, R., Hodgson, P., Marin-Reyes, H., Parker, K., Wilson, J., Baca, M.

“…The Birmingham Irradiation Facility was developed in 2013 at the University of Birmingham using the Medical Physics MC40 cyclotron. It can achieve High…”
Get full text

Development of n+-in-p large-area silicon microstrip sensors for very high radiation environments – ATLAS12 design and initial results by Unno, Y., Edwards, S.O., Pyatt, S., Thomas, J.P., Wilson, J.A., Kierstead, J., Lynn, D., Carter, J.R., Hommels, L.B.A., Robinson, D., Bloch, I., Gregor, I.M., Tackmann, K., Betancourt, C., Jakobs, K., Kuehn, S., Mori, R., Parzefall, U., Wiik-Fucks, L., Clark, A., Ferrere, D., Gonzalez Sevilla, S., Ashby, J., Blue, A., Bates, R., Buttar, C., Doherty, F., Eklund, L., McMullen, T., McEwan, F., O׳Shea, V., Kamada, S., Yamamura, K., Ikegami, Y., Nakamura, K., Takubo, Y., Nishimura, R., Takashima, R., Chilingarov, A., Fox, H., Affolder, A.A., Allport, P.P., Casse, G., Dervan, P., Forshaw, D., Greenall, A., Wonsak, S., Wormald, M., Cindro, V., Kramberger, G., Mandic, I., Mikuz, M., Gorelov, I., Hoeferkamp, M., Palni, P., Seidel, S., Taylor, A., Toms, K., Wang, R., Hessey, N.P., Valencic, N., Arai, Y., Hanagaki, K., Dolezal, Z., Kodys, P., Bohm, J., Mikestikova, M., Bevan, A., Beck, G., Ely, S., Fadeyev, V., Galloway, Z., Grillo, A.A., Martinez-McKinney, F., Ngo, J., Parker, C., Sadrozinski, H.F.-W., Schumacher, D., Seiden, A., French, R., Hodgson, P., Marin-Reyes, H., Parker, K., Paganis, S., Jinnouchi, O., Motohashi, K., Todome, K., Yamaguchi, D., Hara, K., Hagihara, M., Garcia, C., Jimenez, J., Lacasta, C., Marti i Garcia, S., Soldevila, U.

“…We have been developing a novel radiation-tolerant n+-in-p silicon microstrip sensor for very high radiation environments, aiming for application in the high…”
Get full text

Charge collection and field profile studies of heavily irradiated strip sensors for the ATLAS inner tracker upgrade by Hara, K., Allport, P.P., Baca, M., Broughton, J., Chisholm, A., Nikolopoulos, K., Pyatt, S., Thomas, J.P., Wilson, J.A., Kierstead, J., Kuczewski, P., Lynn, D., Arratia, M., Hommels, L.B.A., Ullan, M., Bloch, I., Gregor, I.M., Tackmann, K., Trofimov, A., Yildirim, E., Hauser, M., Jakobs, K., Kuehn, S., Mahboubi, K., Mori, R., Parzefall, U., Clark, A., Ferrere, D., Gonzalez Sevilla, S., Ashby, J., Blue, A., Bates, R., Buttar, C., Doherty, F., McMullen, T., McEwan, F., O'Shea, V., Kamada, S., Yamamura, K., Ikegami, Y., Nakamura, K., Takubo, Y., Unno, Y., Takashima, R., Chilingarov, A., Fox, H., Affolder, A.A., Casse, G., Dervan, P., Forshaw, D., Greenall, A., Wonsak, S., Wormald, M., Cindro, V., Kramberger, G., Mandić, I., Mikuž, M., Gorelov, I., Hoeferkamp, M., Palni, P., Seidel, S., Taylor, A., Toms, K., Wang, R., Hessey, N.P., Valencic, N., Hanagaki, K., Dolezal, Z., Kodys, P., Bohm, J., Mikestikova, M., Bevan, A., Beck, G., Milke, C., Domingo, M., Fadeyev, V., Galloway, Z., Hibbard-Lubow, D., Sadrozinski, H.F.-W., Seiden, A., To, K., French, R., Hodgson, P., Marin-Reyes, H., Parker, K., Jinnouchi, O., Hara, K., Sato, K., Sato, K., Hagihara, M., Iwabuchi, S., Bernabeu, J., Civera, J.V., Garcia, C., Lacasta, C., Marti i. Garcia, S., Rodriguez, D., Santoyo, D., Solaz, C., Soldevila, U.

“…The ATLAS group has evaluated the charge collection in silicon microstrip sensors irradiated up to a fluence of 1×1016neq/cm2, exceeding the maximum of…”
Get full text

Growth arrest-specific gene 6 expression in human breast cancer by Mc Cormack, O, Chung, W Y, Fitzpatrick, P, Cooke, F, Flynn, B, Harrison, M, Fox, E, Gallagher, E, Goldrick, A Mc, Dervan, P A, Mc Cann, A, Kerin, M J

“…Growth arrest-specific gene 6 (Gas6), identified in 1995, acts as the ligand to the Axl/Tyro3 family of tyrosine kinase receptors and exerts mitogenic activity…”
Get full text

Prevention of contrast induced nephropathy: Recommendations for the high risk patient undergoing cardiovascular procedures by Schweiger, Marc J., Chambers, Charles E., Davidson, Charles J., Zhang, Shaoheng, Blankenship, James, Bhalla, Narinder P., Block, Peter C., Dervan, John P., Gasperetti, Christine, Gerber, Lowell, Kleiman, Neal S., Krone, Ronald J., Phillips, William J., Siegel, Robert M., Uretsky, Barry F., Laskey, Warren K.

“…Contrast induced nephropathy (CIN) is the third leading cause of hospital aquired renal failure and is associated with significant morbidity and mortality…”
Get full text

Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands by Dervan, Peter B, White, Sarah, Szewczyk, Jason W, Turner, James M, Baird, Eldon E

“…The design of synthetic ligands that read the information stored in the DNA double helix has been a long-standing goal at the interface of chemistry and…”
Get full text

Formalin-fixed paraffin-embedded clinical tissues show spurious copy number changes in array-CGH profiles by Mc Sherry, EA, Mc Goldrick, A, Kay, EW, Hopkins, AM, Gallagher, WM, Dervan, PA

“…Formalin‐fixed paraffin‐embedded (FFPE) archival clinical specimens are invaluable in discovery of prognostic and therapeutic targets for diseases such as…”
Get full text

Recognition of the DNA minor groove by pyrrole-imidazole polyamides by Dervan, Peter B, Edelson, Benjamin S

“…Many diseases, such as cancer, are related to aberrant gene expression. Regulating transcription by chemical methods could be important in human medicine…”
Get full text

Regulation of gene expression by small molecules by Gottesfeld, Joel M, Neely, Laura, Trauger, John W, Baird, Eldon E, Dervan, Peter B

“…Small molecules that target specific DNA sequences have the potential to control gene expression. Ligands designed for therapeutic application must bind any…”
Get full text

Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma by Wall, Matthew A., Turkarslan, Serdar, Wu, Wei-Ju, Danziger, Samuel A., Reiss, David J., Mason, Mike J., Dervan, Andrew P., Trotter, Matthew W. B., Bassett, Douglas, Hershberg, Robert M., Lomana, Adrián López García de, Ratushny, Alexander V., Baliga, Nitin S.

“…Despite recent advancements in the treatment of multiple myeloma (MM), nearly all patients ultimately relapse and many become refractory to multiple lines of…”
Get full text

Perioperative chemotherapy in the treatment of osteosarcoma: a 26-year single institution review by O'Kane, G M, Cadoo, K A, Walsh, E M, Emerson, R, Dervan, P, O'Keane, C, Hurson, B, O'Toole, G, Dudeney, S, Kavanagh, E, Eustace, S, Carney, D N

“…Chemotherapy in the multimodality treatment of osteosarcoma has improved survival. Reported outcomes on adult patients are limited. Poor necrosis rates post…”
Get full text

Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelines by Cserni, G., Amendoeira, I., Apostolikas, N., Bellocq, J.P., Bianchi, S., Bussolati, G., Boecker, W., Borisch, B., Connolly, C.E., Decker, T., Dervan, P., Drijkoningen, M., Ellis, I.O., Elston, C.W., Eusebi, V., Faverly, D., Heikkila, P., Holland, R., Kerner, H., Kulka, J., Jacquemier, J., Lacerda, M., Martinez-Penuela, J., De Miguel, C., Peterse, J.L., Rank, F., Regitnig, P., Reiner, A., Sapino, A., Sigal-Zafrani, B., Tanous, A.M., Thorstenson, S., Zozaya, E., Wells, C.A.

“…Controversies and inconsistencies regarding the pathological work-up of sentinel lymph nodes (SNs) led the European Working Group for Breast Screening…”
Get full text

Results with p-type pixel sensors with different geometries for the HL-LHC by Allport, P.P., Bates, R., Butter, C., Casse, G., Dervan, P.J., Forshaw, D., Tsurin, I.

“…Pixel detectors will be extensively used for the four innermost layers of the upgraded ATLAS experiment at the future High Luminosity LHC (HL-LHC) at CERN. The…”
Get full text

Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes by Trauger, J W, Dervan, P B

Get more information

Update of the annealing scenario for irradiated silicon p-in-n microstrip sensors by Dervan, P.J., Wigglesworth, C., Vossebeld, J., Casse, G., Affolder, A., Greenall, A.

“…The configuration of almost all silicon microstrip sensors instrumenting the tracker detectors of the current experiments in LHC is with readout from implanted…”
Get full text

Planar pixel detector module development for the HL-LHC ATLAS pixel system by Bates, Richard L., Buttar, C., Stewart, A., Blue, A., Doonan, K., Ashby, J., Casse, G., Dervan, P., Forshaw, D., Tsurin, I., Brown, S., Pater, J.

“…The ATLAS pixel detector for the HL-LHC requires the development of large area pixel modules that can withstand doses up to 1016 1MeVneqcm−2. The area of the…”
Get full text

The silicon microstrip sensors of the ATLAS semiconductor tracker by Ahmad, A., Albrechtskirchinger, Z., Alonso, J., Barr, A.J., Beck, G.A., Brodbeck, T.J., Bruckman De Renstrom, P., Buttar, C.M., Carpentieri, C., Carter, J.R., Charlton, D.G., Ciocio, A., Civera, J.V., Clark, A.G., Costa, M.J., Dabrowski, W., Dawson, I., Demirkoz, B., Dolezal, Z., Dorholt, O., Duerdoth, I.P., Escobar, C., Feld, L., Fortin, R., Fox, H., Fujita, K., Fuster, J., García-Navarro, J.E., Gonzalez, S., Goodrick, M.J., Grigson, C., Haber, C., Hara, K., Harper, R.S., Hauff, D., Hill, J.C., Holt, S., Horazdovsky, T., Hornung, M., Hovland, K.M., Ikegami, Y., Iwata, Y., Jackson, J.N., Jakobs, K., Johansen, L.G., Jones, R.W.L., Jovanovic, P., Kaplon, J., Ketterer, C., Kindervaag, I.M., Kohriki, T., Kohout, Z., Koperny, S., van der Kraaij, E., Kramberger, G., Llosá, G., Ludwig, I., Ludwig, J., Lutz, G., Macpherson, A., McMahon, S.J., Macina, D., Magrath, C.A., Malecki, P., Matsuo, T., Meinhardt, J., Mellado, B., Mikestikova, M., Mistry, J., Mitsou, V., Moorhead, G., Morgan, D., Morone, M.C., Morris, J., Moser, H.-G., Nakano, I., Niinikoski, T., Pernegger, H., Pospisil, S., Ratoff, P.N., Reznicek, P., Runge, K., Sadrozinski, H.F.W., Schieck, J., Seiden, A., Shinma, S., Sloan, T., Snow, S.W., Solar, M., Solberg, A., Sospedra, L., Stastny, J., Stelzer, F., Taylor, G., Tomeda, Y., Turala, M., Wells, P.S., Wu, S.L., Žontar, D., Zsenei, A.

“…This paper describes the AC-coupled, single-sided, p-in-n silicon microstrip sensors used in the Semiconductor Tracker (SCT) of the ATLAS experiment at the…”
Get full text