Search Results - "DERMODY, T. S"

Attachment and cell entry of mammalian orthoreovirus by Guglielmi, K M, Johnson, E M, Stehle, T, Dermody, T S

“…Mammalian orthoreoviruses (reoviruses) serve as a tractable model system for studies of viral pathogenesis. Reoviruses infect virtually all mammals, but cause…”
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Reovirus Binding to Cell Surface Sialic Acid Potentiates Virus-Induced Apoptosis by Connolly, J L, Barton, E S, Dermody, T S

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Identification of Carbohydrate-Binding Domains in the Attachment Proteins of Type 1 and Type 3 Reoviruses by Chappell, J D, Duong, J L, Wright, B W, Dermody, T S

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Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2 by Rodgers, S E, Barton, E S, Oberhaus, S M, Pike, B, Gibson, C A, Tyler, K L, Dermody, T S

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Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis by Oberhaus, S M, Smith, R L, Clayton, G H, Dermody, T S, Tyler, K L

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Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1 by Tyler, K L, Squier, M K, Rodgers, S E, Schneider, B E, Oberhaus, S M, Grdina, T A, Cohen, J J, Dermody, T S

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Reovirus ςNS Protein Is Required for Nucleation of Viral Assembly Complexes and Formation of Viral Inclusions by Becker, Michelle M., Goral, Mehmet I., Hazelton, Paul R., Baer, Geoffrey S., Rodgers, Steven E., Brown, Earl G., Coombs, Kevin M., Dermody, Terence S.

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Role of oxidative damage in the pathogenesis of viral infections of the nervous system by Valyi-Nagy, T, Dermody, T S

“…Oxidative stress, primarily due to increased generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), is a feature of many viral…”
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Infectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 protein by Nibert, M L, Chappell, J D, Dermody, T S

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Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses by DERMODY, T. S, NIBERT, M. L, WETZEL, J. D, XIAO TONG, FIELDS, B. N

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Molecular mechanisms of persistent infection by reovirus by Dermody, T S

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AP-3 Directs the Intracellular Trafficking of HIV-1 Gag and Plays a Key Role in Particle Assembly by Dong, Xinhong, Li, Hua, Derdowski, Aaron, Ding, Lingmei, Burnett, Atuhani, Chen, Xuemin, Peters, Timothy R., Dermody, Terence S., Woodruff, Elvin, Wang, Jaang-Jiun, Spearman, Paul

“…Gag proteins direct the process of retroviral particle assembly and form the major protein constituents of the viral core. The matrix region of the HIV-1 Gag…”
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Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes by Tyler, K L, Squier, M K, Brown, A L, Pike, B, Willis, D, Oberhaus, S M, Dermody, T S, Cohen, J J

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Crystal structure of reovirus attachment protein sigma 1 reveals evolutionary relationship to adenovirus fiber by Chappell, J D, Prota, A E, Dermody, T S, Stehle, T

“…Reovirus attaches to cellular receptors with the sigma 1 protein, a fiber-like molecule protruding from the 12 vertices of the icosahedral virion. The crystal…”
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Fatal Hemophagocytic Lymphohistiocytosis Associated with Epstein-Barr Virus Infection in a Patient with a Novel Mutation in the Signaling Lymphocytic Activation Molecule—Associated Protein by Halasa, Natasha B., Whitlock, James A., McCurley, Thomas L., Smith, Jarrod A., Zhu, Quili, Ochs, Hans, Dermody, Terence S., Crow, James E.

“…Individuals with X-linked lymphoproliferative disease are susceptible to severe Epstein-Barr virus (EBV) infections that are often fatal. Mutations in…”
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Group A Streptococcal Necrotizing Fasciitis Following Varicella in Children: Case Reports and Review by Wilson, Gregory J., Talkington, Deborah F., Gruber, William, Edwards, Kathryn, Dermody, Terence S.

“…We report four cases of necrotizing fasciitis that occurred following varicella in children ranging in age from 2 to 8 years. The only organism isolated from…”
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Cathepsin L and Cathepsin B Mediate Reovirus Disassembly in Murine Fibroblast Cells by Ebert, Daniel H., Deussing, Jan, Peters, Christoph, Dermody, Terence S.

“…After attachment to receptors, reovirus virions are internalized by endocytosis and exposed to acid-dependent proteases that catalyze viral disassembly…”
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Junction Adhesion Molecule Is a Receptor for Reovirus by Barton, Erik S, Forrest, J.Craig, Connolly, Jodi L, Chappell, James D, Liu, Yuan, Schnell, Frederick J, Nusrat, Asma, Parkos, Charles A, Dermody, Terence S

“…Virus attachment to cells plays an essential role in viral tropism and disease. Reovirus serotypes 1 and 3 differ in the capacity to target distinct cell types…”
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Efficiency of viral entry determines the capacity of murine erythroleukemia cells to support persistent infections by mammalian reoviruses by Wetzel, J D, Chappell, J D, Fogo, A B, Dermody, T S

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The Reovirus S4 Gene 3′ Nontranslated Region Contains a Translational Operator Sequence by Michelle Mochow-Grundy, Terence S. Dermody

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