Search Results - "DERESE, Inge"

AKIpredictor, an online prognostic calculator for acute kidney injury in adult critically ill patients: development, validation and comparison to serum neutrophil gelatinase-associated lipocalin by Flechet, Marine, Güiza, Fabian, Schetz, Miet, Wouters, Pieter, Vanhorebeek, Ilse, Derese, Inge, Gunst, Jan, Spriet, Isabel, Casaer, Michaël, Van den Berghe, Greet, Meyfroidt, Geert

“…Purpose Early diagnosis of acute kidney injury (AKI) remains a major challenge. We developed and validated AKI prediction models in adult ICU patients and made…”
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Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial by Hermans, Greet, MD, Casaer, Michael P, MD, Clerckx, Beatrix, PT, Güiza, Fabian, PhD, Vanhullebusch, Tine, PT, Derde, Sarah, PhD, Meersseman, Philippe, MD, Derese, Inge, BSc, Mesotten, Dieter, MD, Wouters, Pieter J, MSc, Van Cromphaut, Sophie, MD, Debaveye, Yves, MD, Gosselink, Rik, PhD, Gunst, Jan, MD, Wilmer, Alexander, MD, Van den Berghe, Greet, Dr MD, Vanhorebeek, Ilse, PhD

“…Summary Background Patients who are critically ill can develop so-called intensive-care unit acquired weakness, which delays rehabilitation. Reduced muscle…”
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Insufficient Autophagy Contributes to Mitochondrial Dysfunction, Organ Failure, and Adverse Outcome in an Animal Model of Critical Illness by GUNST, Jan, DERESE, Inge, AERTGEERTS, Annelies, VERVERS, Eric-Jan, WAUTERS, Andy, VAN DEN BERGHE, Greet, VANHOREBEEK, Ilse

“…Increasing evidence implicates mitochondrial dysfunction as an early, important event in the pathogenesis of critical illness-induced multiple organ failure…”
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Insufficient Activation of Autophagy Allows Cellular Damage to Accumulate in Critically Ill Patients by Vanhorebeek, Ilse, Gunst, Jan, Derde, Sarah, Derese, Inge, Boussemaere, Magaly, Güiza, Fabian, Martinet, Wim, Timmermans, Jean-Pierre, D'Hoore, André, Wouters, Pieter J, Van den Berghe, Greet

“…Insufficient autophagy resulting in inadequate clearance of cellular damage could explain lack of recovery from organ failure in the prolonged critically ill…”
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Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness by Vanhorebeek, Ilse, Derese, Inge, Gunst, Jan, Wouters, Pieter J, Hermans, Greet, Van den Berghe, Greet

“…Critical illness is hallmarked by neuroendocrine alterations throughout ICU stay. We investigated whether the neuroendocrine axes recover after ICU discharge…”
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Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children? by Vanhorebeek, Ilse, Malarvannan, Govindan, Güiza, Fabian, Poma, Giulia, Derese, Inge, Wouters, Pieter J., Joosten, Koen, Verbruggen, Sascha, Jorens, Philippe G., Covaci, Adrian, Van den Berghe, Greet

“…[Display omitted] •Exposure of critically ill children to DEHP in the PICU decreased over the years.•Reduced DEHP exposure in the PICU did not result in…”
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Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study by Van Dyck, Lisa, Vanhorebeek, Ilse, Wilmer, Alexander, Schrijvers, An, Derese, Inge, Mebis, Liese, Wouters, Pieter J, Van den Berghe, Greet, Gunst, Jan, Casaer, Michaël P

“…In two recent randomized controlled trials, withholding parenteral nutrition early in critical illness improved outcome as compared to early…”
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Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate by Goossens, ChloÃ, Weckx, Ruben, Derde, Sarah, Vander Perre, Sarah, Derese, Inge, Van Veldhoven, Paul P, Ghesquière, Bart, Van den Berghe, Greet, Langouche, Lies

“…Abstract Background Muscle weakness is a complication of critical illness which hampers recovery. In critically ill mice, supplementation with the ketone body…”
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C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery by Ingels, Catherine, Langouche, Lies, Dubois, Jasperina, Derese, Inge, Vander Perre, Sarah, Wouters, Pieter J., Gunst, Jan, Casaer, Michaël, Güiza, Fabian, Vanhorebeek, Ilse, Van den Berghe, Greet

“…Purpose Withholding parenteral nutrition (PN) early in critical illness, late-PN, has shown to prevent infections despite a higher peak C-reactive protein…”
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Early Parenteral Nutrition Evokes a Phenotype of Autophagy Deficiency in Liver and Skeletal Muscle of Critically Ill Rabbits by Derde, Sarah, Vanhorebeek, Ilse, Güiza, Fabian, Derese, Inge, Gunst, Jan, Fahrenkrog, Birthe, Martinet, Wim, Vervenne, Hilke, Ververs, Eric-Jan, Larsson, Lars, Van den Berghe, Greet

“…Muscular and hepatic abnormalities observed in artificially fed critically ill patients strikingly resemble the phenotype of autophagy-deficient mice…”
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Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial by Coppens, Grégoire, Vanhorebeek, Ilse, Verlinden, Ines, Derese, Inge, Wouters, Pieter J, Joosten, Koen F., Verbruggen, Sascha C., Güiza, Fabian, Van den Berghe, Greet

“…Critically ill children requiring intensive care suffer from impaired physical/neurocognitive development 2 y later, partially preventable by omitting early…”
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The clinical potential of GDF15 as a “ready-to-feed indicator” for critically ill adults by Van Dyck, Lisa, Gunst, Jan, Casaer, Michaël P, Peeters, Bram, Derese, Inge, Wouters, Pieter J, de Zegher, Francis, Vanhorebeek, Ilse, Van den Berghe, Greet

“…Abstract Background Circulating growth-differentiation factor-15 (GDF15), a cellular stress marker, abruptly increases during critical illness, but its later…”
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Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition by Thiessen, Steven E, Derde, Sarah, Derese, Inge, Dufour, Thomas, Vega, Chloé Albert, Langouche, Lies, Goossens, Chloë, Peersman, Nele, Vermeersch, Pieter, Vander Perre, Sarah, Holst, Jens J, Wouters, Pieter J, Vanhorebeek, Ilse, Van den Berghe, Greet

“…Critical illness is hallmarked by muscle wasting and disturbances in glucose, lipid, and amino acid homeostasis. Circulating concentrations of glucagon, a…”
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Impact of Duration of Critical Illness on the Adrenal Glands of Human Intensive Care Patients by Boonen, Eva, Langouche, Lies, Janssens, Thomas, Meersseman, Philippe, Vervenne, Hilke, De Samblanx, Emilie, Pironet, Zoë, Van Dijck, Lisa, Vander Perre, Sarah, Derese, Inge, Van den Berghe, Greet

“…Context: Adrenal insufficiency is considered to be prevalent during critical illness, although the pathophysiology, diagnostic criteria, and optimal…”
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The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies by Gunst, Jan, De Bruyn, Astrid, Jacobs, An, Langouche, Lies, Derese, Inge, Dulfer, Karolijn, Güiza, Fabian, Garcia Guerra, Gonzalo, Wouters, Pieter J, Joosten, Koen F, Verbruggen, Sascha C, Vanhorebeek, Ilse, Van den Berghe, Greet

“…Withholding parenteral nutrition (PN) until one week after PICU admission facilitated recovery from critical illness and protected against emotional and…”
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Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study by Jacobs, An, Derese, Inge, Vander Perre, Sarah, Wouters, Pieter J., Verbruggen, Sascha, Billen, Jaak, Vermeersch, Pieter, Garcia Guerra, Gonzalo, Joosten, Koen, Vanhorebeek, Ilse, Van den Berghe, Greet

“…Purpose Increased systemic cortisol availability during adult critical illness is determined by reduced binding-proteins and suppressed breakdown rather than…”
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Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis by Lories, Rik J U, Derese, Inge, Luyten, Frank P

“…Joint ankylosis is a major cause of disability in the human spondyloarthropathies. Here we report that this process partially recapitulates embryonic…”
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Obesity attenuates inflammation, protein catabolism, dyslipidaemia, and muscle weakness during sepsis, independent of leptin by Vankrunkelsven, Wouter, Derde, Sarah, Gunst, Jan, Vander Perre, Sarah, Declerck, Emiel, Pauwels, Lies, Derese, Inge, Van den Berghe, Greet, Langouche, Lies

“…Background Muscle weakness is a frequently occurring complication of sepsis, associated with increased morbidity and mortality. Interestingly, obesity…”
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The Role of Autophagy in Critical Illness-induced Liver Damage by Thiessen, Steven E., Derese, Inge, Derde, Sarah, Dufour, Thomas, Pauwels, Lies, Bekhuis, Youri, Pintelon, Isabel, Martinet, Wim, Van den Berghe, Greet, Vanhorebeek, Ilse

“…Mitochondrial dysfunction and endoplasmic reticulum (ER) stress, which activates the unfolded protein response (UPR), mediate critical illness-induced organ…”
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DNA methylation alterations in muscle of critically ill patients by Van Dyck, Lisa, Güiza, Fabian, Derese, Inge, Pauwels, Lies, Casaer, Michaël P., Hermans, Greet, Wouters, Pieter J., Van den Berghe, Greet, Vanhorebeek, Ilse

“…Background Intensive care unit (ICU)‐acquired weakness can persist beyond ICU stay and has been associated with long‐term functional impairment of ICU…”
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