Search Results - "DERENZINI, M."

Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer by Brighenti, E, Calabrese, C, Liguori, G, Giannone, F A, Trerè, D, Montanaro, L, Derenzini, M

“…Chronic inflammation is an established risk factor for the onset of cancer, and the inflammatory cytokine IL-6 has a role in tumorigenesis by enhancing…”
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The AgNORs by Derenzini, M

“…The structure and the function of interphase AgNORs and the importance of the “AgNOR” parameter in tumor pathology have been reviewed. Interphase AgNORs are…”
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Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate by Scala, F, Brighenti, E, Govoni, M, Imbrogno, E, Fornari, F, Treré, D, Montanaro, L, Derenzini, M

“…Many drugs currently used in chemotherapy work by hindering the process of ribosome biogenesis. In tumors with functional p53, the inhibition of ribosome…”
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The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells by Donati, G, Bertoni, S, Brighenti, E, Vici, M, Treré, D, Volarevic, S, Montanaro, L, Derenzini, M

“…Data on the relationship between ribosome biogenesis and p53 function indicate that the tumour suppressor can be activated by either nucleolar disruption or…”
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High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy by Treré, D., Brighenti, E., Donati, G., Ceccarelli, C., Santini, D., Taffurelli, M., Montanaro, L., Derenzini, M.

“…Background: Triple-negative breast cancer (TNBC) is an aggressive disease, nevertheless exhibiting a high response rate to chemotherapy. Since the…”
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Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer by Montanaro, L, Brigotti, M, Clohessy, J, Barbieri, S, Ceccarelli, C, Santini, D, Taffurelli, M, Calienni, M, Teruya-Feldstein, J, Trerè, D, Pandolfi, PP, Derenzini, M

“…Dyskerin is a nucleolar protein, altered in dyskeratosis congenita, which carries out two separate functions, both fundamental for proliferating cells. One…”
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Chromatin structure in situ: the contribution of DNA ultrastructural cytochemistry by Derenzini, M, Olins, A L, Olins, D E

“…Ultrastructural studies conducted in situ using conventional transmission electron microscopy have had relatively little impact on defining the structural…”
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P.08.16: Early Onset Colorectal Cancer vs Sporadic Colorectal Cancer: A Clinicopathological and Molecular Comparison by Eusebi, L.H, Ceccarelli, C, Artesiani, M.L, Montanaro, L, Derenzini, M, Dall’Olio, F, Ardizzoni, A, Biasco, G, Adua, D, Bazzoli, F, Ricciardiello, L

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Prognostic relevance of a novel semiquantitative classification of Bcl2 immunohistochemical expression in human infiltrating ductal carcinomas of the breast by Treré, D, Montanaro, L, Ceccarelli, C, Barbieri, S, Cavrini, G, Santini, D, Taffurelli, M, Derenzini, M

“…Background: Bcl2 is an important prognostic parameter in human breast cancer. However, the evaluation of Bcl2 expression by immunohistochemistry is carried out…”
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The Feulgen reaction 75 years on by Chieco, P, Derenzini, M

“…The Feulgen reaction proposed by Feulgen and Rossenbeck 75 years ago is one of the cytohistochemical reactions most widely used in biology and medicine. It…”
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The prognostic value of the AgNOR parameter in human breast cancer depends on the pRb and p53 status by Derenzini, M, Ceccarelli, C, Santini, D, Taffurelli, M, Treré, D

“…Background: The amount of argyrophilic nucleolar organiser regions (AgNORs) represents a cell kinetics parameter used in tumour pathology for prognostic…”
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Hyperoxia fully protects mitochondria of explanted livers by Sgarbi, G., Giannone, F., Casalena, G. A., Baracca, A., Baldassare, M., Longobardi, P., Caraceni, P., Derenzini, M., Lenaz, G., Trerè, D., Solaini, Giancarlo

“…Liver ischemia-reperfusion injury is still an open problem in many clinical circumstances, including surgery and transplantation. This study investigates how…”
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Nucleolar function and size in cancer cells by Derenzini, M, Trere, D, Pession, A, Montanaro, L, Sirri, V, Ochs, RL

“…We have have studied the relationship between nucleolar function and size and cell doubling time in cancer cells. Seven human cancer cell lines characterized…”
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Different effects of ribosome biogenesis inhibition on cell proliferation in retinoblastoma protein- and p53-deficient and proficient human osteosarcoma cell lines by Montanaro, L., Mazzini, G., Barbieri, S., Vici, M., Nardi-Pantoli, A., Govoni, M., Donati, G., Treré, D., Derenzini, M.

“…  Objectives: To evaluate the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to the RB and p53 status…”
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The quantity of nucleolar proteins nucleolin and protein B23 is related to cell doubling time in human cancer cells by Derenzini, M, Sirri, V, Trerè, D, Ochs, R L

“…The quantity of the silver-stained nucleolar proteins (AgNOR proteins) measured in situ in cytohistologic preparations is related to the rapidity of cell…”
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P.1.23: CELL PROLIFERATION ACTIVITY OF OESOPHAGEAL SQUAMOUS EPITHELIUM IN ERD IS REDUCED COMPARED TO NERD by Calabrese, C, Montanaro, L, Liguori, G, Brighenti, E, Vici, M, Gionchetti, P, Rizzello, F, Campieri, M, Trerè, D, Derenzini, M

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The asialoglycoprotein receptor in human hepatocellular carcinomas: its expression on proliferating cells by TRERE, D, FIUME, L, BADIALI DE GIORGI, L, DI STEFANO, G, MIGALDI, M, DERENZINI, M

“…The expression of the asialoglycoprotein receptor (ASGP-R) on human hepatocellular carcinoma (HCC) cells might be exploited to reduce the extrahepatic toxicity…”
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Endoscopic appearance of GERD: Putative role of cell proliferation by Calabrese, C, Trerè, D, Fabbri, A, Cenacchi, G, Vici, M, Derenzini, M, Di Febo, G

“…Abstract Background Erosive esophagitis is a frequent endoscopic feature in patients with gastro-oesophageal reflux disease. However, most of patients with…”
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Enhanced telomere shortening in transformed lymphoblasts from patients with X linked dyskeratosis by Montanaro, L, Tazzari, P L, Derenzini, M

“…Aim: Dyskeratosis congenita (DC) is characterised by the failure of those tissues that are rapidly dividing in the adult, particularly the skin, mucosae, and…”
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Nucleolus, Ribosomes, and Cancer by Montanaro, Lorenzo, Treré, Davide, Derenzini, Massimo

“…The complex aspects linking the nucleolus and ribosome biogenesis to cancer are reviewed here. The available evidence indicates that the morphological and…”
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