Search Results - "DER POLL, Tom Van"

Ultrafast Long-Range Charge Separation in Organic Semiconductor Photovoltaic Diodes by Gélinas, Simon, Rao, Akshay, Kumar, Abhishek, Smith, Samuel L., Chin, Alex W., Clark, Jenny, van der Poll, Tom S., Bazan, Guillermo C., Friend, Richard H.

“…Understanding the charge-separation mechanism in organic photovoltaic cells (OPVs) could facilitate optimization of their overall efficiency. Here we report…”
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Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo by van Zoelen, Marieke A D, Yang, Huan, Florquin, Sandrine, Meijers, Joost C M, Akira, Shizuo, Arnold, Bernd, Nawroth, Peter P, Bierhaus, Angelika, Tracey, Kevin J, van der Poll, Tom

“…High-mobility group box 1 (HMGB-1) has been reported as a "late" proinflammatory mediator in sepsis. In vitro data have shown that HMGB-1 can induce activation…”
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The role of platelets in sepsis by de Stoppelaar, Sacha F, van 't Veer, Cornelis, van der Poll, Tom

“…Platelets are small circulating anucleate cells that are of crucial importance in haemostasis. Over the last decade, it has become increasingly clear that…”
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The coagulation system and its function in early immune defense by van der Poll, Tom, Herwald, Heiko

“…Blood coagulation has a Janus-faced role in infectious diseases. When systemically activated, it can cause serious complications associated with high morbidity…”
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Pathogenesis and Pathophysiology of Pneumococcal Meningitis by Mook-Kanamori, Barry B, Geldhoff, Madelijn, van der Poll, Tom, van de Beek, Diederik

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study by Lankelma, Jacqueline M., van Vught, Lonneke A., Belzer, Clara, Schultz, Marcus J., van der Poll, Tom, de Vos, Willem M., Wiersinga, W. Joost

“…Purpose The intestinal microbiota has emerged as a virtual organ with essential functions in human physiology. Antibiotic-induced disruption of the microbiota…”
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A short contemporary history of disseminated intravascular coagulation by Levi, Marcel, van der Poll, Tom

“…Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic intravascular activation of coagulation, leading to a widespread…”
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Influenza-Induced Expression of Indoleamine 2,3-Dioxygenase Enhances Interleukin-10 Production and Bacterial Outgrowth during Secondary Pneumococcal Pneumonia by van der Sluijs, Koenraad F., Nijhuis, Monique, Levels, Johannes H. M., Florquin, Sandrine, Mellor, Andrew L., Jansen, Henk M., der Poll, Tom van, Lutter, René

“…BackgroundAirway infection with influenza virus induces local expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO), which has…”
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Asthma and coagulation by de Boer, J. Daan, Majoor, Christof J., van 't Veer, Cornelis, Bel, Elisabeth H.D., van der Poll, Tom

“…Asthma is a chronic airway disease characterized by paroxysmal airflow obstruction evoked by irritative stimuli on a background of allergic lung inflammation…”
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Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome by Michels, Erik H. A., Chouchane, Osoul, de Brabander, Justin, de Vos, Alex F., Faber, Daniël R., Douma, Renée A., Smit, Eva R., Wiersinga, W. Joost, Biggelaar, Maartje van den, Poll, Tom van der, Hoogendijk, Arie J.

“…Introduction Neutrophils play a dichotomous role in community-acquired pneumonia (CAP), providing protection and potentially causing damage. Existing research…”
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Severe Sepsis and Septic Shock by Angus, Derek C, van der Poll, Tom

“…Sepsis, a complex physiological and metabolic response to infection, is a common reason for admission to an intensive care unit. This review examines the…”
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Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis by Brouwer, Matthijs C, MD, de Gans, Jan, MD, Heckenberg, Sebastiaan GB, MD, Zwinderman, Aeilko H, Prof, van der Poll, Tom, Prof, van de Beek, Diederik, Dr

“…Summary Streptococcus pneumoniae and Neisseria meningitidis can cause sepsis and meningitis. Several risk factors for pneumococcal and meningococcal disease…”
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Burkholderia pseudomallei Tropism and the Melioidosis Road Map by Wiersinga, W. Joost , van der Poll, Tom 

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Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome by KUIPERS, Maria T, ASLAMI, Hamid, BRESSER, Paul, LEEMANS, Jaklien C, DER POLL, Tom Van, SCHULTZ, Marcus J, WIELAND, Catharina W, JANCZY, John R, DER SLUIJS, Koenraad F. Van, VLAAR, Alexander P. J, WOLTHUIS, Esther K, CHOI, Goda, ROELOFS, Joris J. T. H, FLAVELL, Richard A, SUTTERWALA, Fayyaz S

“…The innate immune response is important in ventilator-induced lung injury (VILI) but the exact pathways involved are not elucidated. The authors studied the…”
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Expression Profile and Function of Triggering Receptor Expressed on Myeloid Cells-1 during Melioidosis by Wiersinga, W. Joost, Veer, Cees van't, Wieland, Catharina W., Gibot, Sebastien, Hooibrink, Berend, Day, Nicholas P., Peacock, Sharon J., Poll, Tom van der

“…Background. Triggering receptor expressed on myeloid cells—1 (TREM-1) amplifies Toll-like receptor-—nitiated responses against pathogens. We aimed to…”
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Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia by Schuurman, Alex R, Reijnders, Tom DY, Saris, Anno, Ramirez Moral, Ivan, Schinkel, Michiel, de Brabander, Justin, van Linge, Christine, Vermeulen, Louis, Scicluna, Brendon P, Wiersinga, W Joost, Vieira Braga, Felipe A, van der Poll, Tom

“…The exact immunopathophysiology of community-acquired pneumonia (CAP) caused by SARS-CoV-2 (COVID-19) remains clouded by a general lack of relevant disease…”
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The gut microbiota as a modulator of innate immunity during melioidosis by Lankelma, Jacqueline M, Birnie, Emma, Weehuizen, Tassili A F, Scicluna, Brendon P, Belzer, Clara, Houtkooper, Riekelt H, Roelofs, Joris J T H, de Vos, Alex F, van der Poll, Tom, Budding, Andries E, Wiersinga, W Joost

“…Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an emerging cause of pneumonia-derived sepsis in the tropics. The gut…”
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Coagulation and sepsis by Levi, Marcel, MD, van der Poll, Tom, MD

“…Abstract Severe sepsis is almost invariably associated with systemic activation of coagulation. There is ample evidence that demonstrates a wide-ranging…”
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Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis by van Zoelen, Marieke A. D, Vogl, Thomas, Foell, Dirk, Van Veen, Suzanne Q, van Till, Jan W. O, Florquin, Sandrine, Tanck, Michael W, Wittebole, Xavier, Laterre, Pierre-Francois, Boermeester, Marja A, Roth, Johannes, van der Poll, Tom

“…Myeloid-related protein-8 (MRP8) and MRP14 can form heterodimers that elicit a variety of inflammatory responses. We showed that MRP8/14 is a ligand for…”
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Sepsis: deriving biological meaning and clinical applications from high-dimensional data by Schuurman, Alex R., Reijnders, Tom D. Y., Kullberg, Robert F. J., Butler, Joe M., van der Poll, Tom, Wiersinga, W. Joost

“…The pathophysiology of sepsis is multi-facetted and highly complex. As sepsis is a leading cause of global mortality that still lacks targeted therapies,…”
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