Search Results - "DENNIS, I. F"

Long-term trends in catchment organic carbon and nitrogen exports from three acidified catchments in Nova Scotia, Canada by Clair, T. A, Dennis, I. F, Vet, R, Laudon, H

“…We sampled two streams in southwestern Nova Scotia from 1983 to 2004 and one stream from 1992 to 2004 for total organic carbon (TOC) and nitrogen (TN) in order…”
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Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer by Boote, D J, Dennis, I F, Twentyman, P R, Osborne, R J, Laburte, C, Hensel, S, Smyth, J F, Brampton, M H, Bleehen, N M

“…To determine the maximum-tolerated dose (MTD) and toxicity of PSC 833 infusion administered with etoposide for 5 days in patients with cancer, and to determine…”
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Past and future changes to acidified eastern Canadian lakes: A geochemical modeling approach by Clair, T.A., Aherne, J., Dennis, I.F., Gilliss, M., Couture, S., McNicol, D., Weeber, R., Dillon, P.J., Keller, W., Jeffries, D.S., Page, S., Timoffee, K., Cosby, B.J.

“…As SO 2 emissions are being reduced in North America, it has become important to know how rapidly the surface water chemistry of aquatic systems will recover…”
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Probable changes in lake chemistry in Canada’s Atlantic Provinces under proposed North American emission reductions by Clair, T. A., Dennis, I. F., Cosby, B. J.

“…Atlantic Canada, located in the extreme north-eastern portion of North America, receives acid precipitation from all major acid emission sources on the eastern…”
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Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients by LAURENCE, V. M, WARD, R, DENNIS, I. F, BLEEHEN, N. M

“…Nicotinamide and carbogen breathing are both effective radiosensitisers in experimental tumour models and are even more effective in combination. This study…”
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Protein binding modulates inhibition of the epidermal growth factor receptor kinase and DNA synthesis by tyrphostins by HOFFMAN, R, DENNIS, I. F, DONALDSON, J

“…Inhibition of growth factor-stimulated DNA synthesis carried out in defined medium is often compared with inhibition of serum-stimulated DNA synthesis so as to…”
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Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer by DENNIS, I. F, RAMSAY, J. R. S, WORKMAN, P, BLEEHEN, N. M

“…The effect of combining the oxygen-transport-modifying drug BW12C with mitomycin C was investigated in a phase 1 study of 26 patients with advanced…”
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The carotenoids β-carotene, canthaxanthin and zeaxanthin inhibit macrophage-mediated LDL oxidation by Carpenter, Keri L.H, van der Veen, Carina, Hird, Rachel, Dennis, Ian F, Ding, Tina, Mitchinson, Malcolm J

“…Human monocyte-macrophages were incubated for 24 h in Ham's F-10 medium with human low-density lipoprotein (LDL) in the presence or absence of β-carotene,…”
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Testing the MAGIC acid rain model in highly organic, low-conductivity waters using multiple calibrations by Dennis, Ian F, Clair, Thomas A, Cosby, Bernard J

“…Accurate predictions of acid precipitation effects on water resources are important in order to allow a better understanding of various pollution control…”
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Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy by Horsman, M R, Høyer, M, Honess, D J, Dennis, I F, Overgaard, J

“…Healthy human volunteers orally ingested escalating doses of up to 6 g nicotinamide in capsule form on an empty stomach. Some side-effects were seen although…”
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Pentoxifylline: its pharmacokinetics and ability to improve tumour perfusion and radiosensitivity in mice by Honess, D J, Dennis, I F, Bleehen, N M

“…The pharmacokinetics of pentoxifylline and its three major metabolites were measured after intraperitoneal administration of 10 mg/g or 100 mg/kg of drug in…”
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Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidised LDL on human monocyte-macrophages by Carpenter, Keri L.H., Dennis, Ian F., Challis, Iain R., Osborn, David P., Macphee, Colin H., Leake, David S., Arends, Mark J., Mitchinson, Malcolm J.

“…The death of macrophages contributes to atheroma formation. Oxidation renders low-density lipoprotein (LDL) cytotoxic to human monocyte-macrophages…”
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Distribution patterns of mercury in lakes and rivers of northeastern North America by Dennis, Ian F, Clair, Thomas A, Driscoll, Charles T, Kamman, Neil, Chalmers, Ann, Shanley, Jamie, Norton, Stephen A, Kahl, Steve

“…We assembled 831 data points for total mercury (Hg(t)) and 277 overlapping points for methyl mercury (CH3Hg+) in surface waters from Massachussetts, USA to the…”
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Oral alpha-tocopherol supplementation inhibits lipid oxidation in established human atherosclerotic lesions by Carpenter, Keri L H, Kirkpatrick, Peter J, Weissberg, Peter L, Challis, Iain R, Dennis, Ian F, Freeman, Mark A, Mitchinson, Malcolm J

“…Much experimental evidence suggests that lipid oxidation is important in atherogenesis and in epidemiological studies dietary antioxidants appear protective…”
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Using technology in the courtroom by Saylor, F. Dennis, IV, Small, Daniel I

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Using technology in the courtroom by Saylor, F. Dennis, IV, Small, Daniel I

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Rural Industrialization: The Impact of Industrialization on Two Rural Communities in Western Ireland by Josling, Tim

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Trials and technology by Saylor, F. Dennis, IV, Small, Daniel I

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A chronology helps you tell the 'story' effectively by Saylor, F. Dennis, IV, Small, Daniel I

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Tips for putting together the trial notebook by Saylor, F. Dennis, IV, Smal, Daniel I

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