Search Results - "DENG, Mario"

An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19 by Deng, Mario C

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Web-TCGA: an online platform for integrated analysis of molecular cancer data sets by Deng, Mario, Brägelmann, Johannes, Schultze, Joachim L, Perner, Sven

“…The Cancer Genome Atlas (TCGA) is a pool of molecular data sets publicly accessible and freely available to cancer researchers anywhere around the world…”
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The AlloMap™ genomic biomarker story: 10 years after by Deng, Mario C.

“…Over the last >20 years, we have co‐developed the rationale for the first diagnostic and prognostic leukocyte gene expression profiling (GEP) biomarker test in…”
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Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial by Ardehali, Abbas, Prof, Esmailian, Fardad, Prof, Deng, Mario, Prof, Soltesz, Edward, Prof, Hsich, Eileen, Prof, Naka, Yoshifumi, Prof, Mancini, Donna, Prof, Camacho, Margarita, Prof, Zucker, Mark, Prof, Leprince, Pascal, Prof, Padera, Robert, Prof, Kobashigawa, Jon, Prof

“…Summary Background The Organ Care System is the only clinical platform for ex-vivo perfusion of human donor hearts. The system preserves the donor heart in a…”
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Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II by Crespo-Leiro, Maria G, Stypmann, Jörg, Schulz, Uwe, Zuckermann, Andreas, Mohacsi, Paul, Bara, Christoph, Ross, Heather, Parameshwar, Jayan, Zakliczyński, Michal, Fiocchi, Roberto, Hoefer, Daniel, Colvin, Monica, Deng, Mario C, Leprince, Pascal, Elashoff, Barbara, Yee, James P, Vanhaecke, Johan

“…A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study,…”
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FirebrowseR: an R client to the Broad Institute’s Firehose Pipeline by Deng, Mario, Brägelmann, Johannes, Kryukov, Ivan, Saraiva-Agostinho, Nuno, Perner, Sven

“…Abstract With its Firebrowse service (http://firebrowse.org/) the Broad Institute is making large-scale multi-platform omics data analysis results publicly…”
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A peripheral blood transcriptome biomarker test to diagnose functional recovery potential in advanced heart failure by Deng, Mario C

“…Heart failure (HF) is a complex clinical syndrome that causes systemic hypoperfusion and failure to meet the body's metabolic demands. In an attempt to…”
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Gene-Expression Profiling for Rejection Surveillance after Cardiac Transplantation by Pham, Michael X, Teuteberg, Jeffrey J, Kfoury, Abdallah G, Starling, Randall C, Deng, Mario C, Cappola, Thomas P, Kao, Andrew, Anderson, Allen S, Cotts, William G, Ewald, Gregory A, Baran, David A, Bogaev, Roberta C, Elashoff, Barbara, Baron, Helen, Yee, James, Valantine, Hannah A

“…Patients were assigned to monitoring for rejection after cardiac transplantation either according to the standard practice of endomyocardial biopsies or with…”
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Association between preoperative peripheral blood mononuclear cell gene expression profiles, early postoperative organ function recovery potential and long-term survival in advanced heart failure patients undergoing mechanical circulatory support by Bondar, Galyna, Togashi, Ryan, Cadeiras, Martin, Schaenman, Joanna, Cheng, Richard K, Masukawa, Lindsay, Hai, Josephine, Bao, Tra-Mi, Chu, Desai, Chang, Eleanor, Bakir, Maral, Kupiec-Weglinski, Sophie, Groysberg, Victoria, Grogan, Tristan, Meltzer, Joseph, Kwon, Murray, Rossetti, Maura, Elashoff, David, Reed, Elaine, Ping, Pei Pei, Deng, Mario C

“…Multiorgan dysfunction syndrome contributes to adverse outcomes in advanced heart failure (AdHF) patients after mechanical circulatory support (MCS)…”
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Usefulness of Immunosuppression for Giant Cell Myocarditis by Cooper, Leslie T., MD, Hare, Joshua M., MD, Tazelaar, Henry D., MD, Edwards, William D., MD, Starling, Randall C., MD, Deng, Mario C., MD, Menon, Santosh, MD, Mullen, G. Martin, MD, Jaski, Brian, MD, Bailey, Kent R., PhD, Cunningham, Madeleine W., PhD, Dec, G. William, MD

“…Giant cell myocarditis (GCM) is a rare and highly lethal disorder. The only multicenter case series with treatment data lacked cardiac function assessments and…”
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Concordance Among Pathologists in the Second Cardiac Allograft Rejection Gene Expression Observational Study (CARGO II) by CRESPO-LEIRO, Maria G, ZUCKERMANN, Andreas, STYPMANN, Joerg, HOEFER, Daniel, LEHMKUHL, Hans, DENG, Mario C, LEPRINCE, Pascal, BERRY, Gerald, MARBOE, Charles C, STEWART, Susan, TAZELAAR, Henry D, BARON, Helen M, BARA, Christoph, COLEMAN, Ian-Charles, VANHAECKE, Johan, MOHACSI, Paul, SCHULZ, Uwe, BOYLE, Andrew, ROSS, Heather J, PARAMESHWAR, Jayan, ZAKLICZYNSKI, Michael, FIOCCHI, Roberto

“…There has been no large evaluation of the ISHLT 2004 acute cellular rejection grading scheme for heart graft endomyocardial biopsy specimens (EMBs). We…”
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Protein kinetic signatures of the remodeling heart following isoproterenol stimulation by Lam, Maggie P Y, Wang, Ding, Lau, Edward, Liem, David A, Kim, Allen K, Ng, Dominic C M, Liang, Xiangbo, Bleakley, Brian J, Liu, Chenguang, Tabaraki, Jason D, Cadeiras, Martin, Wang, Yibin, Deng, Mario C, Ping, Peipei

“…Protein temporal dynamics play a critical role in time-dimensional pathophysiological processes, including the gradual cardiac remodeling that occurs in…”
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Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer by Brägelmann, Johannes, Klümper, Niklas, Offermann, Anne, von Mässenhausen, Anne, Böhm, Diana, Deng, Mario, Queisser, Angela, Sanders, Christine, Syring, Isabella, Merseburger, Axel S, Vogel, Wenzel, Sievers, Elisabeth, Vlasic, Ignacija, Carlsson, Jessica, Andrén, Ove, Brossart, Peter, Duensing, Stefan, Svensson, Maria A, Adler, David, Kirfel, Jutta, Perner, Sven

“…The Mediator complex is a multiprotein assembly, which serves as a hub for diverse signaling pathways to regulate gene expression. Because gene expression is…”
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An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms by Parkes, Michael D., Aliabadi, Arezu Z., Cadeiras, Martin, Crespo-Leiro, Maria G., Deng, Mario, Depasquale, Eugene C., Goekler, Johannes, Kim, Daniel H., Kobashigawa, Jon, Loupy, Alexandre, Macdonald, Peter, Potena, Luciano, Zuckermann, Andreas, Halloran, Philip F.

“…We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype…”
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Cardiac Amyloidosis: Diagnosis and Treatment Strategies by Tuzovic, Mirela, Yang, Eric H., Baas, Arnold S., Depasquale, Eugene C., Deng, Mario C., Cruz, Daniel, Vorobiof, Gabriel

“…Cardiac amyloidosis in the United States is most often due to myocardial infiltration by immunoglobulin protein, such as in AL amyloidosis, or by the protein…”
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Discovery of non‐HLA antibodies associated with cardiac allograft rejection and development and validation of a non‐HLA antigen multiplex panel: From bench to bedside by Butler, Carrie L., Hickey, Michelle J., Jiang, Ning, Zheng, Ying, Gjertson, David, Zhang, Qiuheng, Rao, Ping, Fishbein, Gregory A., Cadeiras, Martin, Deng, Mario C., Banchs, Hector L., Torre, Guillermo, DeNofrio, David, Eisen, Howard J., Kobashigawa, Jon, Starling, Randall C., Kfoury, Abdallah, Van Bakel, Adrian, Ewald, Gregory, Balazs, Ivan, Baas, Arnold S., Cruz, Daniel, Ardehali, Reza, Biniwale, Reshma, Kwon, Murray, Ardehali, Abbas, Nsair, Ali, Ray, Bryan, Reed, Elaine F.

“…We analyzed humoral immune responses to nonhuman leukocyte antigen (HLA) after cardiac transplantation to identify antibodies associated with allograft…”
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Understanding the correlation between DSA, complement activation and antibody mediated rejection in heart transplant recipients by Zhang, Qiuheng, Hickey, Michelle, Drogalis-Kim, Diana, Zheng, Ying, Gjertson, David, Cadeiras, Martin, Khuu, Tam, Baas, Arnold S, Depasquale, Eugene C, Halnon, Nancy J, Perens, Gregory, Alejos, Juan, Cruz, Daniel, Ali, Nsair, Shemin, Richard, Kwon, Murray, Fishbein, Michael C, Ardehali, Abbas, Deng, Mario, Reed, Elaine F

“…BACKGROUNDDonor specific HLA antibodies (DSA) are associated with increased rates of rejection and of graft failure in cardiac transplantation. The goal of…”
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Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma by Heinemann, Frauke G, Tolkach, Yuri, Deng, Mario, Schmidt, Doris, Perner, Sven, Kristiansen, Glen, Müller, Stefan C, Ellinger, Jörg

“…MicroRNAs (miRNA) play a relevant role in carcinogenesis, cancer progression, invasion, and metastasis. Thus, they can serve as diagnostic/prognostic…”
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Heart Failure Therapies for End-Stage Chemotherapy–Induced Cardiomyopathy by Mukku, Roy B., MD, Fonarow, Gregg C., MD, Watson, Karol E., MD, PhD, Ajijola, Olujimi A., MD, PhD, Depasquale, Eugene C., MD, Nsair, Ali, MD, Baas, Arnold S., MD, Deng, Mario C., MD, Yang, Eric H., MD

“…Highlights • The incidence of chemotherapy-induced cardiomyopathy (CCMP) will continue to rise with an increasing cancer survivor population. • Limited studies…”
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Variability in Donor-Derived Cell-Free DNA Scores to Predict Mortality in Heart Transplant Recipients - A Proof-of-Concept Study by Kamath, Megan, Shekhtman, Grigoriy, Grogan, Tristan, Hickey, Michelle J, Silacheva, Irina, Shah, Karishma S, Shah, Kishan S, Hairapetian, Adrian, Gonzalez, Diego, Godoy, Giovanny, Reed, Elaine F, Elashoff, David, Bondar, Galyna, Deng, Mario C

“…Over the last decade, expanding use of molecular diagnostics in heart transplantation has allowed implementation of non-invasive surveillance strategies for…”
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