Search Results - "DEMIRIS, Nikolaos"
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Assessing optimal target populations for influenza vaccination programmes: an evidence synthesis and modelling study
Published in PLoS medicine (01-10-2013)“…Influenza vaccine policies that maximise health benefit through efficient use of limited resources are needed. Generally, influenza vaccination programmes have…”
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2
Evaluating the effects of second-dose vaccine-delay policies in European countries: A simulation study based on data from Greece
Published in PloS one (21-04-2022)“…The results of a simulation-based evaluation of several policies for vaccine rollout are reported, particularly focusing on the effects of delaying the second…”
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3
A spatial predictive model for malaria resurgence in central Greece integrating entomological, environmental and social data
Published in PloS one (29-06-2017)“…Malaria constitutes an important cause of human mortality. After 2009 Greece experienced a resurgence of malaria. Here, we develop a model-based framework that…”
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4
The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy
Published in BMC cancer (24-01-2022)“…The gut microbiome is implicated as a marker of response to immune checkpoint inhibitors (ICI) based on preclinical mouse models and preliminary observations…”
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5
Trial to assess the tolerability of using felodipine to upregulate autophagy as a treatment of Huntington’s disease (FELL-HD): a phase II, single-centre, open-label, dose-finding trial protocol
Published in BMJ open (21-08-2024)“…IntroductionHuntington’s disease (HD) is an autosomal dominant neurodegenerative disorder that presents with a progressive movement disorder along with…”
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6
Evaluating the frequency of asymptomatic Ebola virus infection
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26-05-2017)“…The potential for asymptomatic infection from Ebola viruses has long been questioned. Knowing the proportion of infections that are asymptomatic substantially…”
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7
A modeling framework for the analysis of the SARS‐CoV2 transmission dynamics
Published in Statistics in medicine (15-10-2024)“…Despite the progress in medical data collection the actual burden of SARS‐CoV‐2 remains unknown due to under‐ascertainment of cases. This was apparent in the…”
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8
Sample size determination for prediction models via learning‐type curves
Published in Statistics in medicine (20-07-2024)“…This article is concerned with sample size determination methodology for prediction models. We propose to combine the individual calculations via learning‐type…”
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Contemporary statistical inference for infectious disease models using Stan
Published in Epidemics (01-12-2019)“…•Rigorous likelihood-based inference is challenging in epidemic models.•Recent developments in statistical machine learning include HMC and VB.•HMC and VB may…”
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Bayesian epidemic models for spatially aggregated count data
Published in Statistics in medicine (10-09-2017)“…Epidemic data often possess certain characteristics, such as the presence of many zeros, the spatial nature of the disease spread mechanism, environmental…”
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Lethal COG6‐CDG in neonatal patient with arachnodactyly, joint contractures, and skin manifestations: Founder mutation in the Southeastern European population?
Published in Pediatric dermatology (01-03-2022)“…Herein, we report a lethal case of the ultra‐rare COG6‐congenital disorder of glycosylation (CDG) presenting with skin manifestations (scaling and erosions)…”
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NIMG-55. PREDICTING SITES OF TUMOR PROGRESSION IN THE INVASIVE MARGIN OF GLIOBLASTOMAS (PRAM-GBM STUDY): AN INTERIM ANALYSIS OF A MULTI-CENTER IMAGING BIOMARKER STUDY
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)“…Abstract INTRODUCTION Although glioblastoma cells extend throughout the brain, virtually all patients die from local progressive disease. This progressive…”
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13
Bayesian epidemic models for spatially aggregated count data: C. MALESIOS ET AL
Published in Statistics in medicine (10-09-2017)Get full text
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14
Inference and model determination for temperature-driven non-linear ecological models
Published in Environmental and ecological statistics (01-09-2022)“…This paper is concerned with a contemporary Bayesian approach to the effect of temperature on developmental rates. We develop statistical methods using recent…”
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15
Survival extrapolation using the poly-Weibull model
Published in Statistical methods in medical research (01-04-2015)“…Recent studies of (cost-) effectiveness in cardiothoracic transplantation have required estimation of mean survival over the lifetime of the recipients. In…”
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A quantitative analysis of the spatial and temporal evolution patterns of the bluetongue virus outbreak in the island of Lesvos, Greece, in 2014
Published in Transboundary and emerging diseases (01-09-2020)“…Bluetongue virus (BTV) causes an infectious disease called bluetongue, a vector‐borne viral disease of ruminants, which has major implications and causes…”
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The PARTNER trial of neoadjuvant olaparib with chemotherapy in triple-negative breast cancer
Published in Nature (London) (30-05-2024)“…PARTNER is a prospective, phase II–III, randomized controlled clinical trial that recruited patients with triple-negative breast cancer 1 , 2 , who were…”
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Abstract OT2-24-01: PARTNER: Randomised, phase II/III trial to evaluate the safety and efficacy of the addition of olaparib to platinum-based neoadjuvant chemotherapy in triple negative and/or germline BRCA mutated breast cancer patients
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Abstract Background: Triple Negative Breast Cancers (TNBC) are a biologically diverse and aggressive subgroup lacking targeted therapy. Germline BRCA (gBRCA)…”
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19
Evaluating the frequency of asymptomatic Ebola virus infection
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26-05-2017)“…The potential for asymptomatic infection from Ebola viruses has long been questioned. Knowing the proportion of infections that are asymptomatic substantially…”
Get full text
Journal Article -
20
Evaluating the effects of second-dose vaccine-delay policies in European countries: A simulation study based on data from Greece
Published in PloS one (01-01-2022)“…The results of a simulation-based evaluation of several policies for vaccine rollout are reported, particularly focusing on the effects of delaying the second…”
Get full text
Journal Article