Search Results - "DEMEULE, M"

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep‐2 by Régina, A, Demeule, M, Ché, C, Lavallée, I, Poirier, J, Gabathuler, R, Béliveau, R, Castaigne, J‐P

“…Background and purpose: Paclitaxel is highly efficacious in the treatment of breast, head and neck, non‐small cell lung cancers and ovarian carcinoma. For…”
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Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1 by Bertrand, Y, Currie, J-C, Poirier, J, Demeule, M, Abulrob, A, Fatehi, D, Stanimirovic, D, Sartelet, H, Castaigne, J-P, Béliveau, R

“…Background: ANG1005 consists of three molecules of paclitaxel conjugated via ester bonds to the 19-amino-acid peptide Angiopep-2. The new chemical agent has…”
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Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction by Barakat, Stéphane, Turcotte, Sandra, Demeule, Michel, Lachambre, Marie-Paule, Régina, Anthony, Baggetto, Loris G., Béliveau, Richard

“…We have investigated the involvement of P-glycoprotein (P-gp)/caveolin-1 interaction in the regulation of brain endothelial cells (EC) migration and…”
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Interaction and influence of child and family characteristics upon success of weight management treatment by Bernstein, Ruth, Getzoff, E., Gelfand, K., Demeule-Hayes, M., Scheimann, A.

“…Purpose Interventions to address childhood obesity demonstrate moderate effects at best. Previous research has focused on factors of the intervention that…”
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Stimulation of tPA-dependent provisional extracellular fibrin matrix degradation by human recombinant soluble melanotransferrin by Bertrand, Y., Demeule, M., Rivard, G.-E., Béliveau, R.

“…Tissue-type plasminogen activator (tPA) and its substrate plasminogen (Plg) are key components in the fibrinolytic system. We have recently demonstrated, that…”
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Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp by Laplante, A, Demeule, M, Murphy, G.F, Béliveau, R

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Expression of the sortilin 1 receptor (SORT1) in healthy and tumor tissues by Roy, G., Kadekar, P., Douglas, L.M., Currie, J.C., Dhillon, J., Cesarone, G., Siderits, R., Kirchner, K., Demeule, M., Marsolais, C.

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139 POSTER Enhanced drug delivery to brain tumors with a new paclitaxel-peptide conjugate by Bichat, F, Demeule, M, Lawrence, B, Raguin, O, Sourzat, B, Gabathuler, R, P. Castaigne, J, Genne, P

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117 POSTER ANG1005, Paclitaxel conjugated to the angiopep brain transport vector for the treatment of brain cancer: preclinical studies by Gabathuler, R, Demeule, M, Regina, A, Che, C, Thomas, F, Abulrob, A, Smith, Q.R, Stanimirovic, D, Beliveau, R, Castaigne, J.P

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Dietary Intake Quality Improvements after Participation in a Multi-Disciplinary Pediatric Weight Management Program by Demeule-Hayes, M, Hogan, K, Winters, M, Getzoff, E, Parrish, J, Rogers, V, Scheimann, A

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Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols by Jodoin, Julie, Demeule, Michel, Béliveau, Richard

“…Many beneficial proprieties have been associated with polyphenols from green tea, such as chemopreventive, anticarcinogenic, antiatherogenic and antioxidant…”
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A Multi-Disciplinary Group Visit Approach to Pediatric Weight Management by Demeule, M, Getzoff, E, Carter, J, Barton, B, Scheimann, A

“…Childhood obesity is the most prevalent nutritional disorder of youth in the US with incidence tripling in adolescents over 30 years. Moreover, it is important…”
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Abstract P6-11-05: ANG4043, a brain-penetrant anti-HER2 mAb increases survival in mice bearing intracranial BT-474 breast tumor cells by Lachowicz, JE, Demeule, M, Regina, A, Houle, E, Tripathy, S, Castaigne, J-P

“…Background: Treatment options for metastatic brain tumors originating from HER2-positive breast disease are limited due to the inability of most anti-tumor…”
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Matrix metalloproteinase inhibition by green tea catechins by Demeule, Michel, Brossard, Mathieu, Pagé, Martine, Gingras, Denis, Béliveau, Richard

“…We have investigated the effects of different biologically active components from natural products, including green tea polyphenols (GTP), resveratrol,…”
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Molecular Study of P-Glycoprotein in Multidrug Resistance Using Surface Plasmon Resonance by Demeule, M., Vachon, V., Delisle, M.C., Beaulieu, E., Averillbates, D., Murphy, G.F., Beliveau, R.

“…P-Glycoprotein is an integral membrane protein which mediates the energy-dependent efflux of various antitumor agents from multidrug-resistant cancer cells…”
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Molecular sizes of amino acid transporters in the luminal membrane from the kidney cortex, estimated by the radiation-inactivation method by Béliveau, R, Demeule, M, Jetté, M, Potier, M

“…Renal brush-border membrane vesicles from rat kidney cortex were irradiated in frozen state with a gamma-radiation source. Initial rates of influx into these…”
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Radiation-inactivation studies on brush-border-membrane vesicles. General considerations, and application to the glucose and phosphate carriers by Béliveau, R, Demeule, M, Ibnoul-Khatib, H, Bergeron, M, Beauregard, G, Potier, M

“…Radiation-inactivation studies were performed on brush-border-membrane vesicles purified from rat kidney cortex. No alteration of the structural integrity of…”
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P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries by Demeule, Michel, Jodoin, Julie, Gingras, Denis, Béliveau, Richard

“…A significant proportion of P-glycoprotein (P-gp) and caveolin was co-localized in caveolae isolated from resistant (CH RC5) cells overexpressing P-gp and from…”
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High transcytosis of melanotransferrin (P97) across the blood–brain barrier by Demeule, Michel, Poirier, Julie, Jodoin, Julie, Bertrand, Yanick, Desrosiers, Richard R., Dagenais, Claude, Nguyen, Tran, Lanthier, Julie, Gabathuler, Reinhard, Kennard, Malcolm, Jefferies, Wilfred A., Karkan, Delara, Tsai, Sam, Fenart, Laurence, Cecchelli, Roméo, Béliveau, Richard

“…The blood–brain barrier (BBB) performs a neuroprotective function by tightly controlling access to the brain; consequently it also impedes access of proteins…”
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Molecular size of the Na+-H+ antiport in renal brush border membranes, as estimated by radiation inactivation by Béliveau, R, Demeule, M, Potier, M

“…The radiation inactivation method was applied to brush border membrane vesicles from rat kidney, in order to estimate the molecular size of the Na+-H+…”
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