Search Results - "DEMETER, Lisa"

Clinical Significance of Human Immunodeficiency Virus Type 1 Replication Fitness by Dykes, Carrie, Demeter, Lisa M

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Reduced Fitness in Cell Culture of HIV-1 with Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Mutations Correlates with Relative Levels of Reverse Transcriptase Content and RNase H Activity in Virions by JIONG WANG, BAMBARA, Robert A, DEMETER, Lisa M, DYKES, Carrie

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Antiretroviral Drug Resistance Testing in Adults Infected with Human Immunodeficiency Virus Type 1: 2003 Recommendations of an International AIDS Society-USA Panel by Hirsch, Martin S., Brun-Vézinet, Françoise, Clotet, Bonaventura, Conway, Brian, Kuritzkes, Daniel R., D'Aquila, Richard T., Demeter, Lisa M., Hammer, Scott M., Johnson, Victoria A., Loveday, Clive, Mellors, John W., Jacobsen, Donna M., Richman, Douglas D.

“…New information about the benefits and limitations of testing for resistance to human immunodeficiency virus (HIV) type 1 (HIV-1) drugs has emerged. The…”
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Differential Equation Modeling of HIV Viral Fitness Experiments: Model Identification, Model Selection, and Multimodel Inference by Miao, Hongyu, Dykes, Carrie, Demeter, Lisa M., Wu, Hulin

“…Many biological processes and systems can be described by a set of differential equation (DE) models. However, literature in statistical inference for DE…”
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No Evidence for Decay of the Latent Reservoir in HIV-1—Infected Patients Receiving Intensive Enfuvirtide-Containing Antiretroviral Therapy by Gandhi, Rajesh T., Bosch, Ronald J., Aga, Evgenia, Albrecht, Mary, Demeter, Lisa M., Dykes, Carrie, Bastow, Barbara, Para, Michael, Lai, Jun, Siliciano, Robert F., Siliciano, Janet D., Eron, Joseph J.

“…Human immunodeficiency virus type 1 (HIV-1) persists in a latent reservoir of infected resting memory CD4 cells in patients receiving antiretroviral therapy.We…”
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HIV-1 Reverse Transcriptase Connection Domain Mutations: Dynamics of Emergence and Implications for Success of Combination Antiretroviral Therapy by von Wyl, Viktor, Ehteshami, Maryam, Demeter, Lisa M., Bürgisser, Philippe, Nijhuis, Monique, Symons, Jori, Yerly, Sabine, Böni, Jürg, Klimkait, Thomas, Schuurman, Rob, Ledergerber, Bruno, Götte, Matthias, Günthard, Huldrych F.

“…Background. Factors promoting the emergence of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) connection domain mutations and their…”
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Epidemiological and Biological Evidence for a Compensatory Effect of Connection Domain Mutation N348I on M184V in HIV-1 Reverse Transcriptase by von Wyl, Viktor, Ehteshami, Maryam, Symons, Jori, Bürgisser, Philippe, Nijhuis, Monique, Demeter, Lisa M., Yerly, Sabine, Böni, Jürg, Klimkait, Thomas, Schuurman, Rob, Ledergerber, Bruno, Götte, Matthias, Günthard, Huldrych F., Günthard, Huldrych F.

“…Background. The connection domain mutation N348I confers resistance to zidovudine (AZT) and is associated with the lamivudine (3TC) mutation M184V. We explored…”
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HIV-1 viral load assays for resource-limited settings by Fiscus, Susan A, Cheng, Ben, Crowe, Suzanne M, Demeter, Lisa, Jennings, Cheryl, Miller, Veronica, Respess, Richard, Stevens, Wendy

“…The authors discuss studies on the low-cost viral load assays that are currently available and their potential for use in resource-limited settings…”
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Antiretroviral Drug Resistance Testing in Adult HIV-1 Infection: Recommendations of an International AIDS Society–USA Panel by Hirsch, Martin S, Brun-Vézinet, Françoise, D'Aquila, Richard T, Hammer, Scott M, Johnson, Victoria A, Kuritzkes, Daniel R, Loveday, Clive, Mellors, John W, Clotet, Bonaventura, Conway, Brian, Demeter, Lisa M, Vella, Stefano, Jacobsen, Donna M, Richman, Douglas D

“…OBJECTIVE Assays for drug resistance testing in human immunodeficiency virus type 1 (HIV-1) infection are now available and clinical studies suggest that viral…”
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Human Immunodeficiency Virus Type 1 Protease Inhibitor Drug-Resistant Mutants Give Discordant Results When Compared in Single-Cycle and Multiple-Cycle Fitness Assays by Dykes, Carrie, Wu, Hulin, Sims, Matthew, Holden-Wiltse, Jeanne, Demeter, Lisa M

“…The replication fitness of HIV-1 drug-resistant mutants has been measured using either multiple-cycle or single-cycle assays (MCAs or SCAs); these assays have…”
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Sequences in the U3 region of human immunodeficiency virus 1 improve efficiency of minus strand transfer in infected cells by Piekna-Przybylska, Dorota, Dykes, Carrie, Demeter, Lisa M, Bambara, Robert A

“…Abstract A tRNA gene-like sequence has been identified near the 3′ end of HIV-1. Two segments of this sequence (motif 9 and segment 1) promoted minus strand…”
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A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less by Hammer, Scott M, Squires, Kathleen E, Hughes, Michael D, Grimes, Janet M, Demeter, Lisa M, Currier, Judith S, Eron, Joseph J, Feinberg, Judith E, Balfour, Henry H, Deyton, Lawrence R, Chodakewitz, Jeffrey A, Fischl, Margaret A, Phair, John P, Pedneault, Louise, Nguyen, Bach-Yen, Cook, Jon C

“…Progress in the field of antiretroviral therapy for human immunodeficiency virus type 1 (HIV-1) infection has brought the end of the zidovudine-monotherapy…”
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Discordant Associations Between SLCO1B1 521T→C and Plasma Levels of Ritonavir-boosted Protease Inhibitors in AIDS Clinical Trials Group Study A5146 by XINYAN ZHANG, TIERNEY, Camlin, ALBRECHT, Mary, DEMETER, Lisa M, MORSE, Gene, DIFRANCESCO, Robin, DYKES, Carrie, HONGYU JIANG, HAAS, David W

“…Among HIV-positive patients prescribed ritonavir-boosted lopinavir, SLCO1B1 521T→C (rs4149056) is associated with increased plasma lopinavir exposure. Protease…”
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Relative replication fitness of efavirenz-resistant mutants of HIV-1: Correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V by Koval, Christine E., Dykes, Carrie, Wang, Jiong, Demeter, Lisa M.

“…Efavirenz resistance during HIV-1 treatment failure is usually associated with the reverse transcriptase mutation K103N. L100I, V108I, or P225H can emerge…”
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Nonnucleoside Reverse Transcriptase Inhibitor-Resistant HIV Is Stimulated by Efavirenz during Early Stages of Infection by JIONG WANG, GANG ZHANG, BAMBARA, Robert A, DONGGE LI, HUA LIANG, HULIN WU, SMITH, Hannah M, LOWE, Nicholas R, DEMETER, Lisa M, DYKES, Carrie

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Augmented HIV-Specific Interferon-Gamma Responses, But Impaired Lymphoproliferation During Interruption of Antiretroviral Treatment Initiated in Primary HIV Infection by Connick, Elizabeth, Bosch, Ronald J, Aga, Evgenia, Schlichtemeier, Rick, Demeter, Lisa M, Volberding, Paul

“…BACKGROUND:Antiretroviral therapy (ART) introduced during primary HIV infection followed by treatment interruption (TI) is postulated to enhance virologic…”
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Immune Reconstitution Syndrome after Successful Treatment of Pneumocystis carinii Pneumonia in a Man with Human Immunodeficiency Virus Type 1 Infection by Koval, Christine E, Gigliotti, Francis, Nevins, Diana, Demeter, Lisa M

“…We describe a 34-year-old man with human immunodeficiency virus infection who received successful treatment of minimally symptomatic Pneumocystis carinii…”
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Modeling and Estimation of Replication Fitness of Human Immunodeficiency Virus Type 1 In Vitro Experiments by Using a Growth Competition Assay by Wu, Hulin, Huang, Yangxin, Dykes, Carrie, Liu, Dacheng, Ma, Jingming, Perelson, Alan S, Demeter, Lisa M

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vFitness: a web-based computing tool for improving estimation of in vitro HIV-1 fitness experiments by Ma, Jingming, Dykes, Carrie, Wu, Tao, Huang, Yangxin, Demeter, Lisa, Wu, Hulin

“…The replication rate (or fitness) between viral variants has been investigated in vivo and in vitro for human immunodeficiency virus (HIV). HIV fitness plays…”
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Antiretroviral Drug Resistance Testing in Adults With HIV Infection: Implications for Clinical Management by Hirsch, Martin S, Conway, Brian, D'Aquila, Richard T, Johnson, Victoria A, Brun-Vézinet, Françoise, Clotet, Bonaventura, Demeter, Lisa M, Hammer, Scott M, Jacobsen, Donna M, Kuritzkes, Daniel R, Loveday, Clive, Mellors, John W, Vella, Stefano, Richman, Douglas D, for the International AIDS Society–USA Panel

“…OBJECTIVES.— To review current knowledge of the biology and clinical implications of human immunodeficiency virus (HIV) resistance to antiretroviral drugs,…”
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