Search Results - "DEMAIMAY, R"

BSE transmission to macaques by Lasmezas, C.I, Deslys, J.P, Demaimay, R, Adjou, I.T, Lamoury, F, Dormont, D, Robain, O, Ironside, J, Hauw, J.J

“…The recent description in the United Kingdom of a new variant of Creutzfeldt-Jacob disease (vCJD) with a unique clinicopathological presentation has raised…”
Get full text

Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals by Demaimay, R, Adjou, K T, Beringue, V, Demart, S, Lasmézas, C I, Deslys, J P, Seman, M, Dormont, D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Immune system-dependent and -independent replication of the scrapie agent by Lasmezas, C.I. (CEA/DSV/DRM/CRSSA, Fontenay-aux-Roses, France.), Cesbron, J.Y, Deslys, J.P, Demaimay, R, Adjou, K.T, Rioux, R, Lemaire, C, Locht, C, Dormont, D

“…Using the severe combined immunodeficiency (SCID) mouse model, we investigated the requirement of the immune system for the development of scrapie after…”
Get full text

Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs by Demaimay, R, Chesebro, B, Caughey, B

“…Five compounds related to Congo Red were found to inhibit generation of protease-resistant prion protein in a cell-free system. In this assay Trypan Blue,…”
Get more information

Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy by Lasmezas, Corinne Ida, Deslys, Jean-Philippe, Demaimay, Remi, Adjou, Karim T, Hauw, Jean-Jacques, Dormont, Dominique

“…1 Service de Neurovirologie, DSV/DRM/CRSSA, Commissariat à l'Energie Atomique, 60-68 avenue Div. Leclerc, BP 6, 92 265 Fontenay-aux-Roses Cedex, France 2…”
Get full text

MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie by KARIM TARIK ADJOU, DEMAIMAY, R, LASMEZAS, C, DESLYS, J.-P, SEMAN, M, DORMONT, D

“…To test the efficacy of a new amphotericin B derivative, MS-8209, in delaying scrapie, hamsters were infected intracerebrally with the 263K scrapie agent and…”
Get full text

Pharmacological studies of a new derivative of amphotericin B, MS-8209, in mouse and hamster scrapie by Demaimay, Remi, Adjou, Karim, Lasmezas, Corinne, Lazarini, Francoise, Cherifi, Kamel, Seman, Michel, Deslys, Jean-Philippe, Dormont, Dominique

“…1 Laboratoire de Neuropathologie Expérimentale et Neurovirologie, CEA/DSV/DPTE/SSA, B.P. 6, 92265, Fontenay aux Roses cedex 2 Laboratoire…”
Get full text

Prospects for the pharmacological treatment of human prion diseases by ADJOU, K. T, DESLYS, J.-P, DEMAIMAY, R, SEMAN, M, DORMONT, D

“…There is currently no effective therapy available for Creutzfeldt-Jakob disease and related prion disorders. However, a limited number of drugs have been found…”
Get full text

Structural Aspects of Congo Red as an Inhibitor of Protease‐Resistant Prion Protein Formation by Demaimay, Rémi, Harper, James, Gordon, Heather, Weaver, Donald, Chesebro, Bruce, Caughey, Byron

“…: Congo red (CR) has been shown to inhibit the accumulation in scrapie‐infected cells of prion protein (PrP) in the abnormal protease‐resistant form (PrP‐res)…”
Get full text

Effectiveness of Polyene Antibiotics in Treatment of Transmissible Spongiform Encephalopathy in Transgenic Mice Expressing Syrian Hamster PrP Only in Neurons by Demaimay, R, Race, R, Chesebro, B

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Differential effects of a new amphotericin B derivative, MS-8209, on mouse bse and scrapie: implications for the mechanism of action of polyene antibiotics by Adjou, K.T., Demaimay, R., Lasmézas, C.I., Seman, M., Deslys, J.-P., Dormont, D.

“…Mice were infected intracerebrally with the bovine spongiform encephalopathy (BSE) or the scrapie agent and treated during 8 weeks postinfection to test the…”
Get full text

Assays of protease-resistant prion protein and its formation by Caughey, B, Horiuchi, M, Demaimay, R, Raymond, G J

Get more information

MS-8209, a water-soluble amphotericin B derivative, affects both scrapie agent replication and PrPres accumulation in Syrian hamster scrapie by Adjou, KT, Demaimay, R, Deslys, JP, Lasmezas, CI, Beringue, V, Demart, S, Lamoury, F, Seman, M, Dormont, D

“…KT Adjou, R Demaimay, JP Deslys, CI Lasmezas, V Beringue, S Demart, F Lamoury, M Seman and D Dormont CEA, Service de Neurovirologie, Fontenay aux Roses,…”
Get full text

Inhibiting scrapie neuroinvasion by polyene antibiotic treatment of SCID mice by Beringue, V, Lasmezas, C.I, Adjou, K.T, Demaimay, R, Lamoury, F, Deslys, J.P, Seman, M, Dormont, D

“…The polyene antibiotic MS-8209 is currently one of the most effective drugs in the treatment of experimental scrapie. However, its mechanism of action and its…”
Get full text

Probing the dynamics of prion diseases with amphotericin B by Adjou, Karim Tarik, Deslys, Jean-Philippe, Demaimay, Rémi, Dormont, Dominique

“…Amphotericin B (AmB) is one of the rare drugs that affect the course of experimental prion diseases and modify the kinetics of abnormal prion protein…”
Get full text

Intérêt des antibiotiques polyéniques dans le traitement des encéphalopathies subaiguës spongiformes transmissibles: Les encéphalopathies spongiformes by KARIM TARIK ADJOU, DEMAIMAY, R, DEMART, S, BERINGUE, V, DESLYS, J.-P, SEMAN, M, DORMONT, D

Get full text

Advantages for polyenic antibiotics in treatment of transmissible subacute spongiform encephalopathies by Adjou, K.T. (Commissariat a l'Energie Atomique, Fontenay aux Roses (France). Service de Neurovirologie), Demaimay, R, Demart, S, Beringue, V, Deslys, J.P, Seman, M, Dormont, D

“…Aujourd'hui il n'existe aucun traitement efficace contre les ESST. L'amphotericine B (AmB) fait partie des rares molecules capables de retarder l'apparition…”
Get full text