Search Results - "DELLA SANTINA, CHARLES C."

MRI Magnetic Field Stimulates Rotational Sensors of the Brain by Roberts, Dale C., Marcelli, Vincenzo, Gillen, Joseph S., Carey, John P., Della Santina, Charles C., Zee, David S.

“…Vertigo in and around magnetic resonance imaging (MRI) machines has been noted for years [1, 2]. Several mechanisms have been suggested to explain these…”
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Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes by Kawashima, Yoshiyuki, Géléoc, Gwenaëlle S G, Kurima, Kiyoto, Labay, Valentina, Lelli, Andrea, Asai, Yukako, Makishima, Tomoko, Wu, Doris K, Della Santina, Charles C, Holt, Jeffrey R, Griffith, Andrew J

“…Inner ear hair cells convert the mechanical stimuli of sound, gravity, and head movement into electrical signals. This mechanotransduction process is initiated…”
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Ionic Direct Current Modulation for Combined Inhibition/Excitation of the Vestibular System by Aplin, Felix P., Singh, Dilawer, Santina, Charles C. Della, Fridman, Gene Y.

“…Objective: Prosthetic electrical stimulation delivered to the vestibular nerve could provide therapy for people suffering from bilateral vestibular…”
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Selective Neuronal Activation by Cochlear Implant Stimulation in Auditory Cortex of Awake Primate by Johnson, Luke A, Della Santina, Charles C, Wang, Xiaoqin

“…Despite the success of cochlear implants (CIs) in human populations, most users perform poorly in noisy environments and music and tonal language perception…”
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Effects of Biphasic Current Pulse Frequency, Amplitude, Duration, and Interphase Gap on Eye Movement Responses to Prosthetic Electrical Stimulation of the Vestibular Nerve by Davidovics, Natan S., Fridman, Gene Y., Chiang, Bryce, Santina, Charles C. Della

“…An implantable prosthesis that stimulates vestibular nerve branches to restore sensation of head rotation and vision-stabilizing reflexes could benefit…”
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Characterization of the 3D angular vestibulo-ocular reflex in C57BL6 mice by Migliaccio, Americo A., Meierhofer, Robert, Della Santina, Charles C.

“…We characterized the three-dimensional angular vestibulo-ocular reflex (3D aVOR) of adult C57BL6 mice during static tilt testing, sinusoidal, and…”
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Virtual labyrinth model of vestibular afferent excitation via implanted electrodes: validation and application to design of a multichannel vestibular prosthesis by Hayden, Russell, Sawyer, Stacia, Frey, Eric, Mori, Susumu, Migliaccio, Americo A., Della Santina, Charles C.

“…To facilitate design of a multichannel vestibular prosthesis that can restore sensation to individuals with bilateral loss of vestibular hair cell function, we…”
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Variation in response dynamics of regular and irregular vestibular-nerve afferents during sinusoidal head rotations and currents in the chinchilla by Kim, Kyu-Sung, Minor, Lloyd B., Santina, Charles C. Della, Lasker, David M.

“…In mammals, vestibular-nerve afferents that innervate only type I hair cells (calyx-only afferents) respond nearly in phase with head acceleration for…”
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Histopathologic Changes of the Inner ear in Rhesus Monkeys After Intratympanic Gentamicin Injection and Vestibular Prosthesis Electrode Array Implantation by Sun, Daniel Q., Lehar, Mohamed, Dai, Chenkai, Swarthout, Lani, Lauer, Amanda M., Carey, John P., Mitchell, Diana E., Cullen, Kathleen E., Santina, Charles C. Della

“…Bilateral vestibular deficiency (BVD) due to gentamicin ototoxicity can significantly impact quality of life and result in large socioeconomic burdens…”
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Unidirectional rotations produce asymmetric changes in horizontal VOR gain before and after unilateral labyrinthectomy in macaques by Ushio, Munetaka, Minor, Lloyd B., Della Santina, Charles C., Lasker, David M.

“…Unilateral vestibular lesions cause marked asymmetry in the horizontal vestibulo-ocular reflex (VOR) during rapid head rotations, with VOR gain being lower for…”
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Adaptation of the vestibulo‐ocular reflex for forward‐eyed foveate vision by Migliaccio, Americo A., Minor, Lloyd B., Santina, Charles C. Della

“…To maintain visual fixation on a distant target during head rotation, the angular vestibulo‐ocular reflex (aVOR) should rotate the eyes at the same speed as…”
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An Implanted Vestibular Prosthesis Improves Spatial Orientation in Animals with Severe Vestibular Damage by Karmali, Faisal, Haburcakova, Csilla, Gong, Wangsong, Della Santina, Charles C, Merfeld, Daniel M, Lewis, Richard F

“…Gravity is a pervasive environmental stimulus, and accurate graviception is required for optimal spatial orientation and postural stability. The primary…”
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Complementary gain modifications of the cervico-ocular (COR) and angular vestibulo-ocular (aVOR) reflexes after canal plugging by Yakushin, Sergei B., Kolesnikova, Olga V., Cohen, Bernard, Ogorodnikov, Dmitri A., Suzuki, Jun-Ichi, Della Santina, Charles C., Minor, Lloyd B., Raphan, Theodore

“…To determine whether the COR compensates for the loss of aVOR gain, independent of species, we studied cynomolgus and rhesus monkeys in which all six…”
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Posture, Gait, Quality of Life, and Hearing with a Vestibular Implant by Chow, Margaret R, Ayiotis, Andrianna I, Schoo, Desi P, Gimmon, Yoav, Lane, Kelly E, Morris, Brian J, Rahman, Mehdi A, Valentin, Nicolas S, Boutros, Peter J, Bowditch, Stephen P, Ward, Bryan K, Sun, Daniel Q, Treviño Guajardo, Carolina, Schubert, Michael C, Carey, John P, Della Santina, Charles C

“…Eight adults with severe vestibular hypofunction underwent implantation of a device that stimulates the semicircular canal branches with continuous information…”
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Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations by Ono, Kazuya, Keller, James, López Ramírez, Omar, González Garrido, Antonia, Zobeiri, Omid A., Chang, Hui Ho Vanessa, Vijayakumar, Sarath, Ayiotis, Andrianna, Duester, Gregg, Della Santina, Charles C., Jones, Sherri M., Cullen, Kathleen E., Eatock, Ruth Anne, Wu, Doris K.

“…Each vestibular sensory epithelium in the inner ear is divided morphologically and physiologically into two zones, called the striola and extrastriola in…”
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A prosthesis utilizing natural vestibular encoding strategies improves sensorimotor performance in monkeys by Wiboonsaksakul, Kantapon Pum, Roberts, Dale C, Della Santina, Charles C, Cullen, Kathleen E

“…Sensory pathways provide complex and multifaceted information to the brain. Recent advances have created new opportunities for applying our understanding of…”
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Binocular 3-D otolith-ocular reflexes: responses of chinchillas to natural and prosthetic stimulation after ototoxic injury and vestibular implantation by Chow, Margaret R, Fernandez Brillet, Celia, Hageman, Kristin N, Roberts, Dale C, Ayiotis, Andrianna I, Haque, Razi M, Della Santina, Charles C

“…The otolith end organs inform the brain about gravitational and linear accelerations, driving the otolith-ocular reflex (OOR) to stabilize the eyes during…”
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Plasticity within non-cerebellar pathways rapidly shapes motor performance in vivo by Mitchell, Diana E., Della Santina, Charles C., Cullen, Kathleen E.

“…Although cerebellar mechanisms are vital to maintain accuracy during complex movements and to calibrate simple reflexes, recent in vitro studies have called…”
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Representations of Time-Varying Cochlear Implant Stimulation in Auditory Cortex of Awake Marmosets ( Callithrix jacchus ) by Johnson, Luke A, Della Santina, Charles C, Wang, Xiaoqin

“…Electrical stimulation of the auditory periphery organ by cochlear implant (CI) generates highly synchronized inputs to the auditory system. It has long been…”
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Cochlear Implant Revisions Over Three Decades of Experience by Andresen, Nicholas S., Shneyderman, Matthew, Bowditch, Stephen P., Wang, Nae-Yuh, Della Santina, Charles C., Sun, Daniel Q., Creighton, Francis X.

“…The indications, technology, and surgical technique for cochlear implantation have evolved over the last three decades. Understanding the risk of cochlear…”
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