Search Results - "DELHEM, Nadira"

INtraoperative photoDYnamic Therapy for GliOblastomas (INDYGO): Study Protocol for a Phase I Clinical Trial by Dupont, Clément, Vermandel, Maximilien, Leroy, Henri-Arthur, Quidet, Mathilde, Lecomte, Fabienne, Delhem, Nadira, Mordon, Serge, Reyns, Nicolas

“…Abstract BACKGROUND Glioblastoma (GBM) is characterized by marked proliferation, major infiltration, and poor prognosis. Despite current treatments, including…”
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All-Trans Retinoic Acid Modulates TLR4/NF-κB Signaling Pathway Targeting TNF-α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer by Soufli, Imene, de Launoit, Yvan, Mahfouf, Hassen, Nakmouche, M’hamed, Nadira, Delhem, Touil-Boukoffa, Chafia, Toumi, Ryma, Boukercha, Aziza, Belkhelfa, Mourad, Belhadef, Said, Saoula, Houria, AitYounes, Sonia, Benkhelifa, Sarra, Rafa, Hayet, Olivier, Morales

“…Colitis associated cancer (CAC) is the colorectal cancer (CRC) subtype that is associated with bowel disease such as ulcerative colitis (UC). The data on role…”
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Novel Therapies Boosting T Cell Immunity in Epstein Barr Virus-Associated Nasopharyngeal Carcinoma by Renaud, Sarah, Lefebvre, Anthony, Mordon, Serge, Moralès, Olivier, Delhem, Nadira

“…Nasopharyngeal carcinoma (NPC) is a malignant tumour of the head and neck affecting localised regions of the world, with the highest rates described in…”
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An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma by Kumar, Abhishek, Pecquenard, Florian, Baydoun, Martha, Quilbé, Alexandre, Moralès, Olivier, Leroux, Bertrand, Aoudjehane, Lynda, Conti, Filomena, Boleslawski, Emmanuel, Delhem, Nadira

“…Photodynamic therapy (PDT) is a two-stage treatment relying on cytotoxicity induced by photoexcitation of a nontoxic dye, called photosensitizer (PS). Using…”
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Folate Receptor Targeted Photodynamic Therapy: A Novel Way to Stimulate Anti-Tumor Immune Response in Intraperitoneal Ovarian Cancer by Baydoun, Martha, Boidin, Léa, Leroux, Bertrand, Vignion-Dewalle, Anne-Sophie, Quilbe, Alexandre, Grolez, Guillaume Paul, Azaïs, Henri, Frochot, Céline, Moralès, Olivier, Delhem, Nadira

“…Photodynamic therapy (PDT) has shown improvements in cancer treatment and in the induction of a proper anti-tumor immune response. However, current…”
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Laser interstitial thermotherapy (LITT) for breast cancer: dosimetry optimization and numerical simulation by Kerbage, Yohan, Rouillès, Julie, Vignion, Anne-Sophie, Delhem, Nadira, Thecua, Elise, Deleporte, Pascal, Collinet, Pierre, Mordon, Serge

“…Surgical treatment is standard for the treatment of small breast cancers. Due to the pain and esthetic sequelae that can follow surgery, minimally invasive…”
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Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis by Oxombre, Bénédicte, Madouri, Fahima, Journé, Anne-Sophie, Ravez, Séverine, Woitrain, Eloise, Odou, Pascal, Duhal, Nathalie, Ninni, Sandro, Montaigne, David, Delhem, Nadira, Vermersch, Patrick, Melnyk, Patricia

“…Multiple Sclerosis (MS) is an autoimmune demyelinating and neurodegenerative disease of the central nervous system (CNS). Current management strategies…”
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Combination of High Dose Hypofractionated Radiotherapy with Anti-PD1 Single Dose Immunotherapy Leads to a Th1 Immune Activation Resulting in a Complete Clinical Response in a Melanoma Patient by Milhem, Clara, Moralès, Olivier, Ingelaere, Céline, Pasquier, David, Mordon, Serge, Mortier, Laurent, Mirabel, Xavier, Delhem, Nadira

“…The development of immunotherapy has recently modified the anti-tumor therapeutic arsenal; particularly, immune checkpoint inhibitors have led to a significant…”
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Control of the Inflammatory Response Mechanisms Mediated by Natural and Induced Regulatory T-Cells in HCV-, HTLV-1-, and EBV-Associated Cancers by Olivier, Morales, Renaud, Sarah, Mrizak, Dhafer, Laurissa, Ouaguia, Nadira, Delhem

“…Virus infections are involved in chronic inflammation and, in some cases, cancer development. Although a viral infection activates the immune system’s response…”
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A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice by Quilbe, Alexandre, Mustapha, Rami, Duchêne, Belinda, Kumar, Abhishek, Werkmeister, Elisabeth, Leteurtre, Emmanuelle, Moralès, Olivier, Jonckheere, Nicolas, Van Seuningen, Isabelle, Delhem, Nadira

“…Pancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a…”
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Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9 by Lhuillier, Claire, Barjon, Clément, Baloche, Valentin, Niki, Toshiro, Gelin, Aurore, Mustapha, Rami, Claër, Laetitia, Hoos, Sylviane, Chiba, Yoichi, Ueno, Masaki, Hirashima, Mitsuomi, Wei, Ming, Morales, Olivier, Raynal, Bertrand, Delhem, Nadira, Dellis, Olivier, Busson, Pierre

“…Extra-cellular galectin-9 (gal-9) is an immuno-modulatory protein with predominant immunosuppressive effects. Inappropriate production of gal-9 has been…”
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Photodynamic Therapy Using a Rose-Bengal Photosensitizer for Hepatocellular Carcinoma Treatment: Proposition for a Novel Green LED-Based Device for In Vitro Investigation by Lefebvre, Anthony, Marhfor, Smail, Baert, Gregory, Deleporte, Pascal, Grolez, Guillaume Paul, Boileau, Marie, Morales, Olivier, Vignoud, Séverine, Delhem, Nadira, Mortier, Laurent, Dewalle, Anne-Sophie

“…Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Despite new treatments, the HCC rate remains important, making it necessary to…”
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Residual Microscopic Peritoneal Metastases after Macroscopic Complete Cytoreductive Surgery for Advanced High-Grade Serous Ovarian Carcinoma: A Target for Folate Receptor Targeted Photodynamic Therapy? by Moinard, Morgane, Augustin, Jeremy, Carrier, Marine, Da Maïa, Elisabeth, Penel, Alix, Belghiti, Jérémie, Nikpayam, Maryam, Gonthier, Clémentine, Canlorbe, Geoffroy, Acherar, Samir, Delhem, Nadira, Frochot, Céline, Uzan, Catherine, Azaïs, Henri

“…Despite conventional treatment combining complete macroscopic cytoreductive surgery (CRS) and systemic chemotherapy, residual microscopic peritoneal metastases…”
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An Efficient Photodynamic Therapy Treatment for Human Pancreatic Adenocarcinoma by Quilbe, Alexandre, Moralès, Olivier, Baydoun, Martha, Kumar, Abhishek, Mustapha, Rami, Murakami, Takashi, Leroux, Bertrand, de Schutter, Clémentine, Thecua, Elise, Ziane, Laurine, Colombeau, Ludovic, Frochot, Céline, Mordon, Serge, Delhem, Nadira

“…To date, pancreatic adenocarcinoma (ADKP) is a devastating disease for which the incidence rate is close to the mortality rate. The survival rate has evolved…”
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Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin‐9 dependent mechanism by Lefebvre, Anthony, Trioën, Camille, Renaud, Sarah, Laine, William, Hennart, Benjamin, Bouchez, Clément, Leroux, Bertrand, Allorge, Delphine, Kluza, Jérôme, Werkmeister, Elisabeth, Grolez, Guillaume Paul, Delhem, Nadira, Moralès, Olivier

“…Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an immunosuppressive impact on the tumour microenvironment. In this study, we…”
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Hepatitis C Virus Improves Human Tregs Suppressive Function and Promotes Their Recruitment to the Liver by Ouaguia, Laurissa, Moralès, Olivier, Aoudjehane, Lynda, Wychowski, Czeslaw, Kumar, Abhishek, Dubuisson, Jean, Calmus, Yvon, Conti, Filomena, Delhem, Nadira

“…The role of regulatory T cells (Tregs) is now well established in the progression of hepatocellular carcinoma (HCC) linked to Hepatitis C virus (HCV)…”
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CD49b, a Major Marker of Regulatory T-Cells Type 1, Predicts the Response to Antiviral Therapy of Recurrent Hepatitis C after Liver Transplantation by Yvon, Calmus, Nadira, Delhem, Filomena, Conti, Fabien, Stenard, Gautier, Goormachtigh, Laurissa, Ouaguia, Lynda, Aoudjehane, Olivier, Morales, Khaldoun, Ghazal, Vivian, Viallon

“…The TRANSPEG study was a prospective study to assess the efficacy of antiviral therapy in patients with a recurrent hepatitis C virus (HCV) after liver…”
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Activation of a helper and not regulatory human CD4+ T cell response by oncolytic H-1 parvovirus by Moralès, Olivier, Richard, Audrey, Martin, Nathalie, Mrizak, Dhafer, Sénéchal, Magalie, Miroux, Céline, Pancré, Véronique, Rommelaere, Jean, Caillet-Fauquet, Perrine, de Launoit, Yvan, Delhem, Nadira

“…H-1 parvovirus (H-1 PV), a rodent autonomous oncolytic parvovirus, has emerged as a novel class of promising anticancer agents, because of its ability to…”
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Response by Delhem, Nadira, Mustapha, Rami

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In vitro Proof of Concept of Photodynamic Therapy Efficiency in the Treatment of Glioblastoma by Gouges, Bastien, Coulardeau, Laura, Grolez, Guillaume, Reyns, Nicolas, Delhem, Nadira

“…5-ALA photodynamic therapy (5-ALA-PDT) could be a novel approach to treat glioblastoma. However, we observed an in vitro resistance of human glioblastoma cells…”
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