Search Results - "DELGADO, Alejandro"

Why could high-pressure breast milk processing improve the life of preterm babies? by Núñez-Delgado, Alejandro, Welti-Chanes, Jorge, Chuck-Hernández, Cristina

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Recent advances and challenges in temperature monitoring and control in microfluidic devices by Dos‐Reis‐Delgado, Alejandro A., Carmona‐Dominguez, Andrea, Sosa‐Avalos, Gerardo, Jimenez‐Saaib, Ivan H., Villegas‐Cantu, Karen E., Gallo‐Villanueva, Roberto C., Perez‐Gonzalez, Víctor H.

“…Temperature is a critical—yet sometimes overlooked—parameter in microfluidics. Microfluidic devices can experience heating inside their channels during…”
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Systematic prediction of genes functionally associated with bacterial retrons and classification of the encoded tripartite systems by Mestre, Mario Rodríguez, González-Delgado, Alejandro, Gutiérrez-Rus, Luis I, Martínez-Abarca, Francisco, Toro, Nicolás

“…Abstract Bacterial retrons consist of a reverse transcriptase (RT) and a contiguous non-coding RNA (ncRNA) gene. One third of annotated retrons carry…”
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Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis by Cairó, Montserrat, Campderrós, Laura, Gavaldà‐Navarro, Aleix, Cereijo, Rubén, Delgado‐Anglés, Alejandro, Quesada‐López, Tania, Giralt, Marta, Villarroya, Joan, Villarroya, Francesc

“…Parkin is an ubiquitin‐E3 ligase that acts as a key component of the cellular machinery for mitophagy. We show here that Parkin expression is reciprocally…”
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Continuous multiplexed phage genome editing using recombitrons by Fishman, Chloe B, Crawford, Kate D, Bhattarai-Kline, Santi, Poola, Darshini, Zhang, Karen, González-Delgado, Alejandro, Rojas-Montero, Matías, Shipman, Seth L

“…Bacteriophage genome editing can enhance the efficacy of phages to eliminate pathogenic bacteria in patients and in the environment. However, current methods…”
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Temporally resolved transcriptional recording in E. coli DNA using a Retro-Cascorder by Lear, Sierra K., Lopez, Santiago C., González-Delgado, Alejandro, Bhattarai-Kline, Santi, Shipman, Seth L.

“…Biological signals occur over time in living cells. Yet most current approaches to interrogate biology, particularly gene expression, use destructive…”
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Prokaryotic reverse transcriptases: from retroelements to specialized defense systems by González-Delgado, Alejandro, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, Toro, Nicolás

“…ABSTRACT Reverse transcriptases (RTs) catalyze the polymerization of DNA from an RNA template. These enzymes were first discovered in RNA tumor viruses in…”
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Simultaneous multi-site editing of individual genomes using retron arrays by González-Delgado, Alejandro, Lopez, Santiago C., Rojas-Montero, Matías, Fishman, Chloe B., Shipman, Seth L.

“…During recent years, the use of libraries-scale genomic manipulations scaffolded on CRISPR guide RNAs have been transformative. However, these existing…”
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Spacer acquisition from RNA mediated by a natural reverse transcriptase-Cas1 fusion protein associated with a type III-D CRISPR–Cas system in Vibrio vulnificus by González-Delgado, Alejandro, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, Toro, Nicolás

“…Abstract The association of reverse transcriptases (RTs) with CRISPR–Cas system has recently attracted interest because the RT activity appears to facilitate…”
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Two Simultaneous Leak Diagnosis in Pipelines Based on Input–Output Numerical Differentiation by Navarro-Díaz, Adrián, Delgado-Aguiñaga, Jorge-Alejandro, Begovich, Ofelia, Besançon, Gildas

“…This paper addresses the two simultaneous leak diagnosis problem in pipelines based on a state vector reconstruction as a strategy to improve water shortages…”
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The Reverse Transcriptases Associated with CRISPR-Cas Systems by Toro, Nicolás, Martínez-Abarca, Francisco, González-Delgado, Alejandro

“…CRISPR (clustered regularly interspaced short palindromic repeats) and associated proteins (Cas) act as adaptive immune systems in bacteria and archaea. Some…”
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Recruitment of Reverse Transcriptase-Cas1 Fusion Proteins by Type VI-A CRISPR-Cas Systems by Toro, Nicolás, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, González-Delgado, Alejandro

“…Type VI CRISPR–Cas systems contain a single effector nuclease (Cas13) that exclusively targets single-stranded RNA. It remains unknown how these systems…”
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An experimental census of retrons for DNA production and genome editing by Khan, Asim G, Rojas-Montero, Matías, González-Delgado, Alejandro, Lopez, Santiago C, Fang, Rebecca F, Crawford, Kate D, Shipman, Seth L

“…Retrons are bacterial immune systems that use reverse-transcribed DNA (RT-DNA) to detect phage infection. They are also deployed for genome editing, where they…”
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UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions by Mestre, Mario Rodríguez, Gao, Linyi Alex, Shah, Shiraz A, López-Beltrán, Adrián, González-Delgado, Alejandro, Martínez-Abarca, Francisco, Iranzo, Jaime, Redrejo-Rodríguez, Modesto, Zhang, Feng, Toro, Nicolás

“…Reverse transcriptases (RTs) are enzymes capable of synthesizing DNA using RNA as a template. Within the last few years, a burst of research has led to the…”
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Molecular Epidemiology and Antimicrobial Resistance of Clostridioides difficile in Hospitalized Patients From Mexico by Aguilar-Zamora, Emmanuel, Weimer, Bart C, Torres, Roberto C, Gómez-Delgado, Alejandro, Ortiz-Olvera, Nayeli, Aparicio-Ozores, Gerardo, Barbero-Becerra, Varenka J, Torres, Javier, Camorlinga-Ponce, Margarita

“…is a global public health problem, which is a primary cause of antibiotic-associated diarrhea in humans. The emergence of hypervirulent and…”
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Objective measured physical activity and metabolic syndrome score in children and adolescents: The UP&DOWN longitudinal study by Sánchez-Delgado, Alejandro, Sánchez-Parente, Sandra, Martínez-Gómez, David, Gómez-Martínez, Sonia, Veiga, Oscar L, Marcos, Ascensión, Castro-Piñero, José, Pérez-Bey, Alejandro

“…We aimed to analyze the cross-sectional and longitudinal association of physical activity (PA) levels and PA patterns with metabolic syndrome score (MetS) in…”
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Hidden effects of high numbers of tourists in protected areas: displacement of foraging top scavengers by Donázar, José A., Cortés‐Avizanda, Ainara, Arrondo, Eneko, Delgado‐González, Alejandro, Ceballos, Olga

“…Protected areas in southern Europe are important for the conservation of large avian scavengers. However, the effects an increasing number of visitors may have…”
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The IMD and Toll canonical immune pathways of Triatoma pallidipennis are preferentially activated by Gram-negative and Gram-positive bacteria, respectively, but cross-activation also occurs by Alejandro, Alvarado-Delgado, Lilia, Juárez-Palma, Jesús, Maritinez-Bartneche, Henry, Rodriguez Mario

“…Antimicrobial peptides (AMPs) participate in the humoral immune response of insects eliminating invasive microorganisms. The immune deficiency pathway (IMD)…”
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Phenotypic and Genotypic Antibiotic Resistance Patterns in Helicobacter pylori Strains From Ethnically Diverse Population in México by Camorlinga-Ponce, Margarita, Gómez-Delgado, Alejandro, Aguilar-Zamora, Emmanuel, Torres, Roberto C, Giono-Cerezo, Silvia, Escobar-Ogaz, Antonio, Torres, Javier

“…strains carry a range of mutations in genes that confer antimicrobial resistance and restrict the available options to treat the infection. Latin America is a…”
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CRISPR/Cas9-Mediated Allele-Specific Disruption of a Dominant COL6A1 Pathogenic Variant Improves Collagen VI Network in Patient Fibroblasts by López-Márquez, Arístides, Morín, Matías, Fernández-Peñalver, Sergio, Badosa, Carmen, Hernández-Delgado, Alejandro, Natera-de Benito, Daniel, Ortez, Carlos, Nascimento, Andrés, Grinberg, Daniel, Balcells, Susanna, Roldán, Mónica, Moreno-Pelayo, Miguel Ángel, Jiménez-Mallebrera, Cecilia

“…Collagen VI-related disorders are the second most common congenital muscular dystrophies for which no treatments are presently available. They are mostly…”
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