Search Results - "DEL SER, Teodoro"
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Social Networks, Social Integration, and Social Engagement Determine Cognitive Decline in Community-Dwelling Spanish Older Adults
Published in The journals of gerontology. Series B, Psychological sciences and social sciences (01-03-2003)“…Objectives. To examine the influence of social networks and social engagement on cognitive decline in a population-based cohort of elderly people, and to…”
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Trajectories of Cognitive Decline and Social Relations
Published in The journals of gerontology. Series B, Psychological sciences and social sciences (01-11-2005)“…We assessed conjoint trajectories of cognitive decline and social relations over 7 years on a representative sample of community-dwelling elderly persons. We…”
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3
A phase II trial of tideglusib in Alzheimer's disease
Published in Journal of Alzheimer's disease (01-01-2015)“…The ARGO study was a phase II, double-blind, placebo controlled, four parallel arm trial of tideglusib in Alzheimer's disease (AD). To prove the clinical…”
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4
Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History
Published in Journal of clinical medicine (01-01-2024)“…The concept of Alzheimer disease (AD)-since its histological discovery by Alzheimer to the present day-has undergone substantial modifications. We conducted a…”
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Tau phosphorylation by glycogen synthase kinase 3β modulates enzyme acetylcholinesterase expression
Published in Journal of neurochemistry (01-06-2021)“…In Alzheimer's disease (AD), the enzyme acetylcholinesterase (AChE) co‐localizes with hyperphosphorylated tau (P‐tau) within neurofibrillary tangles. Having…”
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Impact of individual and neighborhood dimensions of socioeconomic status on the prevalence of mild cognitive impairment over seven-year follow-up
Published in Aging & mental health (04-05-2021)“…Objectives: There is strong evidence about the association between low socioeconomic status (SES) and higher risk of dementia. However, it has not been…”
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Residence, Clinical Features, and Genetic Risk Factors Associated with Symptoms of COVID-19 in a Cohort of Older People in Madrid
Published in Gerontology (Basel) (01-06-2021)“…The older population has been especially affected by the severe acute respiratory syndrome coronavirus 2 pandemic (COVID-19). The aim of the study was to…”
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Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy
Published in Dementia and geriatric cognitive disorders (01-01-2010)“…Nonpharmacological therapies (NPTs) can improve the quality of life (QoL) of people with Alzheimer's disease (AD) and their carers. The objective of this study…”
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Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial
Published in Movement disorders (01-04-2014)“…ABSTRACT It is believed that glycogen synthase kinase‐3 hyperphosphorylates tau protein in progressive supranuclear palsy (PSP). The Tau Restoration on PSP…”
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10
Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review
Published in International Journal of Geriatric Psychiatry (01-05-2021)“…Background Predementia is a heuristic umbrella concept to classify older adults with cognitive impairment who do not suffer dementia. Many diagnostic entities…”
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Oral Microbiota, Its Equilibrium and Implications in the Pathophysiology of Human Diseases: A Systematic Review
Published in Biomedicines (27-07-2022)“…Imbalances of the oral microbiota and dysbiosis have traditionally been linked to the occurrence of teeth and oral diseases. However, recent findings indicate…”
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12
A modified progressive supranuclear palsy rating scale
Published in Movement disorders (01-05-2021)“…© 2021 International Parkinson and Movement Disorder Society. Background: The Progressive Supranuclear Palsy Rating Scale is a prospectively validated…”
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Normative data and determinants for the timed "up and go" test in a population-based sample of elderly individuals without gait disturbances
Published in Journal of geriatric physical therapy (2001) (2008)“…To define the standard performance of elderly people without gait disturbances in the "Timed Up and Go" test (TUG) and investigate its determinants. A…”
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14
MADRID+90 study on factors associated with longevity: Study design and preliminary data
Published in PloS one (17-05-2021)“…The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the…”
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15
Hypoalbuminemia and other prognostic factors of mortality at different time points after ischemic stroke
Published in Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral (01-03-2013)“…The aim of this study was to investigate whether hypoalbuminemia and other risk factors for mortality after stroke have the same or different short (1 month),…”
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Progression of two Progressive Supranuclear Palsy phenotypes with comparable initial disability
Published in Parkinsonism & related disorders (01-09-2019)“…To avoid bias and optimize statistical power of disease-modifying therapeutic trials, it is critical to include homogeneous populations with similar rate of…”
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Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study
Published in The Lancet (British edition) (16-12-2000)“…Dementia with Lewy bodies is a common form of dementia in the elderly, characterised clinically by fluctuating cognitive impairment, attention deficits, visual…”
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Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study
Published in Lancet neurology (01-06-2007)“…Summary Objective To assess the effect of rivastigmine in patients with mild cognitive impairment (MCI) on the time to clinical diagnosis of Alzheimer's…”
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Validation of the seven-minute screen neurocognitive battery for the diagnosis of dementia in a Spanish population-based sample
Published in Dementia and geriatric cognitive disorders (01-01-2006)“…To validate the Seven-Minute Screen Neurocognitive Battery (7MS) in an elderly population-based sample to identify dementia using a new scoring method. Five…”
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Effects of commonly prescribed drugs on cognition and mild cognitive impairment in healthy elderly people
Published in Journal of psychopharmacology (Oxford) (01-08-2019)“…Background: Chronic drug intake has been associated with negative and positive cognitive effects in elderly people, although subjacent conditions may be…”
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